8IG1
Crystal structure of wild-type transthyretin in complex with rafoxanide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 159 | 17310.5 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
| 2 | C, E (A, B) | ~{N}-[3-chloranyl-4-(4-chloranylphenoxy)phenyl]-3,5-bis(iodanyl)-2-oxidanyl-benzamide | non-polymer | 626.0 | 2 | Chemie (OX9) | |||
| 3 | D, F (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A, B: -19 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Met -31 | - | expression tag |
| Arg -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ser -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34621.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1298.0 | |
| All* | Total formula weight | 35919.0 |
