8IG1

Crystal structure of wild-type transthyretin in complex with rafoxanide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Transthyretin	polymer	159	17310.5	2	UniProt (P02766) Pfam (PF00576) In PDB	Homo sapiens (human)	ATTR,Prealbumin,TBPA
2	A, B	~{N}-[3-chloranyl-4-(4-chloranylphenoxy)phenyl]-3,5-bis(iodanyl)-2-oxidanyl-benzamide	non-polymer		626.0	2	Chemie (OX9)
3	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4		water	water		18.0	169	Chemie (HOH)

Sequence modifications

A, B: -19 - 127 (UniProt: P02766)

PDB	External Database	Details
Met -31	-	expression tag
Arg -30	-	expression tag
Gly -29	-	expression tag
Ser -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34621.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1298.0
All*	Total formula weight	35919.0

*Water molecules are not included.