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5ZJD
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BU of 5zjd by Molmil
Lactate dehydrogenase with NADH and MLA
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain, MALONATE ION
Authors:Han, C.W, Jang, S.B.
Deposit date:2018-03-20
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
5ZJE
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BU of 5zje by Molmil
LDHA-mla
Descriptor: L-lactate dehydrogenase A chain, MALONATE ION
Authors:Han, C.W, Jang, S.B.
Deposit date:2018-03-20
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.929 Å)
Cite:Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
5ZJF
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BU of 5zjf by Molmil
LDHA-MA
Descriptor: 5,5'-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2H-1,3-benzodioxole), L-lactate dehydrogenase A chain
Authors:Han, C.W, Jang, S.B.
Deposit date:2018-03-20
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
8A96
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BU of 8a96 by Molmil
SARS Cov2 Spike RBD in complex with Fab47
Descriptor: Fab47 Heavy chain (variable domain), Fab47 Light chain (variable domain), Spike protein S1
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-27
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
8A99
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BU of 8a99 by Molmil
SARS Cov2 Spike in 1-up conformation complex with Fab47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-28
Release date:2023-05-10
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
8A94
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BU of 8a94 by Molmil
SARS CoV2 Spike in the 2-up state in complex with Fab47.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain Variable domain), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-27
Release date:2023-05-03
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
8A95
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BU of 8a95 by Molmil
SARS Cov2 Spike RBD in complex with Fab47
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2022-06-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Immunity, 56, 2023
4N5M
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BU of 4n5m by Molmil
Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha in complexed with acetoacetyl-CoA
Descriptor: ACETOACETYL-COENZYME A, Acetoacetyl-CoA reductase, GLYCEROL
Authors:Kim, J.-E, Kim, S, Kim, K.-J.
Deposit date:2013-10-10
Release date:2013-12-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha
Biochem.Biophys.Res.Commun., 443, 2014
4N5L
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BU of 4n5l by Molmil
Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha
Descriptor: Acetoacetyl-CoA reductase
Authors:Kim, J.-E, Kim, S, Kim, K.-J.
Deposit date:2013-10-10
Release date:2013-12-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha
Biochem.Biophys.Res.Commun., 443, 2014
4N5N
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BU of 4n5n by Molmil
Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha in complexed with NADP
Descriptor: Acetoacetyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kim, J.-E, Kim, S, Kim, K.-J.
Deposit date:2013-10-10
Release date:2013-12-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha
Biochem.Biophys.Res.Commun., 443, 2014
5EY2
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BU of 5ey2 by Molmil
Crystal structure of CodY from Bacillus cereus
Descriptor: GTP-sensing transcriptional pleiotropic repressor CodY
Authors:Han, A, Lee, W.C, Son, J, Kim, S.H, Hwang, K.Y.
Deposit date:2015-11-24
Release date:2016-09-14
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
4MKC
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BU of 4mkc by Molmil
Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378
Descriptor: 5-chloro-N~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine, ALK tyrosine kinase receptor, GLYCEROL
Authors:Lee, C.C, Spraggon, G.
Deposit date:2013-09-04
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer.
Cancer Discov, 4, 2014
4O9C
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BU of 4o9c by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase, COENZYME A
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2014-12-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
4O9A
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BU of 4o9a by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2015-02-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
4O99
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BU of 4o99 by Molmil
Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16
Descriptor: Acetyl-CoA acetyltransferase, GLYCEROL
Authors:Kim, E.J, Kim, J, Kim, S, Kim, K.J.
Deposit date:2014-01-02
Release date:2014-12-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium.
Biochem.Biophys.Res.Commun., 452, 2014
4IWB
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BU of 4iwb by Molmil
Novel Fold of FliC/FliS Fusion Protein
Descriptor: FliC, FliS chimera
Authors:Faham, S.
Deposit date:2013-01-23
Release date:2013-12-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Protein design by fusion: implications for protein structure prediction and evolution.
Acta Crystallogr.,Sect.D, 69, 2013
3ZHD
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BU of 3zhd by Molmil
The crystal structure of single domain antibody 8-4 scaffold.
Descriptor: MG8-4 SCAFFOLD ANTIBODY, SULFATE ION
Authors:Song, H.-N, Woo, E.-J, Lim, H.-K.
Deposit date:2012-12-21
Release date:2014-01-08
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (1.962 Å)
Cite:Directed Evolution of Human Heavy Chain Variable Domain (Vh) Using in Vivo Protein Fitness Filter.
Plos One, 9, 2014
3ZHK
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BU of 3zhk by Molmil
The crystal structure of single domain antibody 2x1 scaffold
Descriptor: MG2X1 SCAFFOLD ANTIBODY, SULFATE ION
Authors:Song, H.-N, Woo, E.-J, Lim, H.-K.
Deposit date:2012-12-22
Release date:2014-01-08
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (1.962 Å)
Cite:Directed Evolution of Human Heavy Chain Variable Domain (Vh) Using in Vivo Protein Fitness Filter.
Plos One, 9, 2014
4RQZ
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BU of 4rqz by Molmil
re-refinement of 1soz, Crystal Structure of DegS protease in complex with an activating peptide
Descriptor: Protease degS, activating peptide
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4RR0
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BU of 4rr0 by Molmil
re-refined 1vcw, CRYSTAL STRUCTURE OF DEGS AFTER BACKSOAKING THE ACTIVATING PEPTIDE
Descriptor: Protease degS
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.054 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4RQY
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BU of 4rqy by Molmil
RE-REFINED STRUCTURE OF 1TE0 - STRUCTURAL ANALYSIS of DEGS, A STRESS SENSOR OF THE BACTERIAL PERIPLASM
Descriptor: PHOSPHATE ION, Protease degS
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4RR1
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BU of 4rr1 by Molmil
re-refinement of entry 1sot, Crystal Structure of the DegS stress sensor
Descriptor: NICKEL (II) ION, PHOSPHATE ION, Protease degS
Authors:Sauer, R.T, Grant, R.A.
Deposit date:2014-11-05
Release date:2015-03-11
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4Z55
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BU of 4z55 by Molmil
Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
Descriptor: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Authors:Lee, C.C, Spraggon, G.
Deposit date:2015-04-02
Release date:2016-02-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
3LCT
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BU of 3lct by Molmil
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALK tyrosine kinase receptor, GLYCEROL
Authors:Lee, C.C.
Deposit date:2010-01-11
Release date:2010-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
5X68
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BU of 5x68 by Molmil
Crystal Structure of Human KMO
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Kim, H.T, Hwang, K.Y.
Deposit date:2017-02-21
Release date:2018-02-21
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Cell Chem Biol, 25, 2018

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