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5X68

Crystal Structure of Human KMO

Summary for 5X68
Entry DOI10.2210/pdb5x68/pdb
Related5X6P 5X6Q 5X6R
DescriptorKynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywordsmonooxygenase, flavin reduction, oxidoreductase
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion outer membrane ; Multi-pass membrane protein : O15229
Total number of polymer chains2
Total formula weight90141.34
Authors
Kim, H.T.,Hwang, K.Y. (deposition date: 2017-02-21, release date: 2018-02-21, Last modification date: 2018-05-02)
Primary citationKim, H.T.,Na, B.K.,Chung, J.,Kim, S.,Kwon, S.K.,Cha, H.,Son, J.,Cho, J.M.,Hwang, K.Y.
Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Cell Chem Biol, 25:426-438.e4, 2018
Cited by
PubMed: 29429898
DOI: 10.1016/j.chembiol.2018.01.008
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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