5X68

Crystal Structure of Human KMO

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Kynurenine 3-monooxygenase	polymer	391	44285.1	2	UniProt (O15229) Pfam (PF01494)	Homo sapiens (Human)	Kynurenine 3-hydroxylase
2	C, D (A, B)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	E, F (A, B)	water	water		18.0	131	Chemie (HOH)

Sequence modifications

A, B: 1 - 374 (UniProt: O15229)

PDB	External Database	Details
Met -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 375	-	expression tag
Ala 376	-	expression tag
Ala 377	-	expression tag
Leu 378	-	expression tag
Glu 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88570.2
Non-Polymers*	Number of molecules	2
	Total formula weight	1571.1
All*	Total formula weight	90141.3

*Water molecules are not included.