6LW1
| Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form | 分子名称: | 2-ethoxy-8-(5-fluoranylpyridin-3-yl)-6-methyl-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purine, Toll-like receptor 7 | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | 登録日 | 2020-02-06 | 公開日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism. Nat Commun, 11, 2020
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6LVZ
| Crystal structure of TLR7/Cpd-3 (SM-394830) complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-2-(2-methoxyethoxy)-9-(pyridin-3-ylmethyl)-7H-purin-8-one, ... | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | 登録日 | 2020-02-06 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism. Nat Commun, 11, 2020
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6LVX
| Crystal structure of TLR7/Cpd-1 (SM-374527) complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-2-butoxy-9-(phenylmethyl)-7H-purin-8-one, ... | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | 登録日 | 2020-02-06 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism. Nat Commun, 11, 2020
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5GSZ
| Crystal Structure of the KIF19A Motor Domain Complexed with Mg-ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF19, MAGNESIUM ION | 著者 | Wang, D, Nitta, R, Hirokawa, N. | 登録日 | 2016-08-18 | 公開日 | 2016-09-28 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A Elife, 5, 2016
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6M04
| Structure of the human homo-hexameric LRRC8D channel at 4.36 Angstroms | 分子名称: | Volume-regulated anion channel subunit LRRC8D | 著者 | Nakamura, R, Kasuya, G, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | 登録日 | 2020-02-20 | 公開日 | 2020-06-17 | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | 主引用文献 | Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation. Commun Biol, 3, 2020
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6LN5
| CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class1) | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-28 | 公開日 | 2020-08-26 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LN9
| CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class2) | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-28 | 公開日 | 2020-08-26 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LN7
| CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class3) | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-28 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LN8
| CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class1) | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-28 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LN6
| CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class2) | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-28 | 公開日 | 2020-08-26 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LLE
| CryoEM structure of SERCA2b WT in E1-2Ca2+-AMPPCP state. | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-23 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LLY
| CryoEM structure of SERCA2b WT in E2-BeF3- state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | 登録日 | 2019-12-24 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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7W7W
| E2 Pi of SERCA2b | 分子名称: | MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, TETRAFLUOROALUMINATE ION | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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7W7U
| The 'Ca2+-unbound' BeF3- of SERCA2b | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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7W7T
| The E1-BeF3- 2Ca2+ of SERCA2b | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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7W7V
| 'late' E2P of SERCA2b | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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7DAA
| Crystal structure of basigin complexed with anti-basigin Fab fragment | 分子名称: | CADMIUM ION, Heavy chain of antibody Fab fragment, Isoform 2 of Basigin, ... | 著者 | Sakuragi, T, Kanai, R, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Toyoshima, C, Nagata, S. | 登録日 | 2020-10-16 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes. Nat.Struct.Mol.Biol., 28, 2021
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7D9Z
| Crystal structure of anti-basigin Fab fragment | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, Heavy chain of antibody Fab fragment, ... | 著者 | Sakuragi, T, Kanai, R, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Toyoshima, C, Nagata, S. | 登録日 | 2020-10-14 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.123 Å) | 主引用文献 | The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes. Nat.Struct.Mol.Biol., 28, 2021
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7E7S
| WT transporter state1 | 分子名称: | CALCIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-02-27 | 公開日 | 2021-09-08 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca 2+ -ATPase SERCA2b. Embo J., 40, 2021
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7YAM
| CryoEM structure of SPCA1a in E2P state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAI
| CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 3 | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, Nanobody head piece of megabody, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAJ
| CryoEM structure of SPCA1a in E1-Mn-AMPPCP state subclass 1 | 分子名称: | Calcium-transporting ATPase type 2C member 1, MANGANESE (II) ION, Nanobody head piece of megabody, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAH
| CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 2 | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7YAG
| CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 1 | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Chen, Z, Watanabe, S, Inaba, K. | 登録日 | 2022-06-28 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus. Sci Adv, 9, 2023
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7DY0
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