6M04

Structure of the human homo-hexameric LRRC8D channel at 4.36 Angstroms

Summary for 6M04

• Entry DOI: 10.2210/pdb6m04/pdb
• EMDB information: 30029
• Descriptor: Volume-regulated anion channel subunit LRRC8D (1 entity in total)
• Functional Keywords: ion channel, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 595867.08

Authors

Nakamura, R.,Kasuya, G.,Yokoyama, T.,Shirouzu, M.,Ishitani, R.,Nureki, O. (deposition date: 2020-02-20, release date: 2020-06-17)

• Primary citation: Nakamura, R.,Numata, T.,Kasuya, G.,Yokoyama, T.,Nishizawa, T.,Kusakizako, T.,Kato, T.,Hagino, T.,Dohmae, N.,Inoue, M.,Watanabe, K.,Ichijo, H.,Kikkawa, M.,Shirouzu, M.,Jentsch, T.J.,Ishitani, R.,Okada, Y.,Nureki, O.; Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.; Commun Biol, 3:240-240, 2020; PubMed: 32415200; DOI: 10.1038/s42003-020-0951-z

Experimental method

ELECTRON MICROSCOPY (4.36 Å)