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6M04

Structure of the human homo-hexameric LRRC8D channel at 4.36 Angstroms

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Volume-regulated anion channel subunit LRRC8Dpolymer86699311.26UniProt (Q7L1W4)
Pfam (PF12534)
Pfam (PF13855)
In PDB
Homo sapiens (Human)Leucine-rich repeat-containing protein 5,Leucine-rich repeat-containing protein 8D
Sequence modifications
A, B, C, D, E, F: 1 - 858 (UniProt: Q7L1W4)
PDBExternal DatabaseDetails
Phe 810Leu 810engineered mutation
Gly 859-expression tag
Thr 860-expression tag
Glu 861-expression tag
Asn 862-expression tag
Leu 863-expression tag
Tyr 864-expression tag
Phe 865-expression tag
Gln 866-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight595867.1
All*Total formula weight595867.1
*Water molecules are not included.

222415

PDB entries from 2024-07-10

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