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7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-14
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEU
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BU of 7leu by Molmil
Structure of importin a2 bound to p65-NLS
Descriptor: Importin subunit alpha-1, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7SZ6
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BU of 7sz6 by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-3
Descriptor: Portal protein
Authors:Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-25
Release date:2022-03-30
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (6.24 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SZ4
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BU of 7sz4 by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-2
Descriptor: Portal protein
Authors:Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-25
Release date:2022-03-30
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SYA
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BU of 7sya by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length
Descriptor: Portal protein
Authors:Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-24
Release date:2022-04-20
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
7SXK
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BU of 7sxk by Molmil
Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length
Descriptor: Portal protein
Authors:Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-11-23
Release date:2022-04-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3.
J.Mol.Biol., 434, 2022
8EMB
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BU of 8emb by Molmil
X-ray crystal structure of Thermosynechococcus elongatus Si3 domain of RNA polymerase RpoC2 subunit
Descriptor: DNA-directed RNA polymerase subunit beta'
Authors:Murakami, K.S, Imashimizu, M, Qayyum, M.Z, Vishwakarma, R.K, Yuzenkova, Y.
Deposit date:2022-09-27
Release date:2022-11-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SYI
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BU of 8syi by Molmil
Cyanobacterial RNAP-EC
Descriptor: DNA (37-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Qayyum, M.Z, Imashimizu, M, Leanca, M, Vishwakarma, R.K, Bradley Riaz, A, Yuzenkova, Y, Murakami, K.S.
Deposit date:2023-05-25
Release date:2023-07-05
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
5HUY
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BU of 5huy by Molmil
Structure of HCMV Small Terminase NLS bound to importin alpha
Descriptor: HCMV small terminase, Importin subunit alpha-1
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2016-01-28
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5HUW
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BU of 5huw by Molmil
Structure of HSV-1 Large Terminase NLS bound to importin alpha
Descriptor: HSV1 large terminase NLS, Importin subunit alpha-1
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2016-01-27
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits.
J.Biol.Chem., 291, 2016
5T94
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BU of 5t94 by Molmil
Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
Descriptor: Guanine nucleotide exchange factor SRM1, Importin subunit alpha
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-09
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.631 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
5TBK
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BU of 5tbk by Molmil
Crystal structure of human importin a3 bound to RCC1
Descriptor: Importin subunit alpha-3, Regulator of chromosome condensation
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
5V5P
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BU of 5v5p by Molmil
Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
6RGV
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BU of 6rgv by Molmil
Truncated FljB phase 2 flagellin
Descriptor: Flagellin
Authors:Lunelli, M, Lokareddy, R.K, Kolbe, M.
Deposit date:2019-04-17
Release date:2020-03-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
Nat Commun, 11, 2020
4QLP
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BU of 4qlp by Molmil
Atomic structure of tuberculosis necrotizing toxin (TNT) complexed with its immunity factor IFT
Descriptor: Alanine and proline rich protein, tuberculosis necrotizing toxin (TNT), immunity factor IFT
Authors:Cingolani, G, Lokareddy, R.K, Sun, J, Siroy, A, Speer, A, Doornbos, K.S, Niederweis, M.
Deposit date:2014-06-12
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD.
Nat.Struct.Mol.Biol., 22, 2015
3GYZ
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BU of 3gyz by Molmil
Crystal structure of IpgC from Shigella flexneri
Descriptor: Chaperone protein ipgC, GLYCEROL, SODIUM ION, ...
Authors:Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
3GZ1
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BU of 3gz1 by Molmil
Crystal structure of IpgC in complex with the chaperone binding region of IpaB
Descriptor: Chaperone protein ipgC, GLYCEROL, Invasin ipaB
Authors:Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
4MBB
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BU of 4mbb by Molmil
Cubic crystal form of PIR1 dual specificity phosphatase core
Descriptor: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2013-08-19
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43
Authors:Doll, S.G, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
6VI1
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BU of 6vi1 by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
Descriptor: Synthetic Fab4 heavy chain, Synthetic Fab4 light chain, Terminase, ...
Authors:Cingolani, G, Lokareddy, R, Ko, Y.
Deposit date:2020-01-11
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6VI2
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BU of 6vi2 by Molmil
Structure of the unaligned Fab4
Descriptor: FAB4 heavy chain, FAB4 light chain
Authors:Cingolani, G, Lokareddy, R, Ko, Y.
Deposit date:2020-01-11
Release date:2020-09-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
8DKR
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BU of 8dkr by Molmil
Pseudomonas-phage E217 TerL nuclease domain
Descriptor: Large terminase protein, MAGNESIUM ION
Authors:Cingolani, G, Lokareddy, R, Hou, D.
Deposit date:2022-07-06
Release date:2022-09-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Terminase Subunits from the Pseudomonas-Phage E217.
J.Mol.Biol., 434, 2022
6XMI
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BU of 6xmi by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
Descriptor: Fab Heavy chain, Fab Light chain, Terminase, ...
Authors:Cingolani, G, Lokareddy, R, Ko, Y.
Deposit date:2020-06-30
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6TK7
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BU of 6tk7 by Molmil
Femtosecond to millisecond structural changes in a light-driven sodium pump: Dark structure in acidic conditions
Descriptor: EICOSANE, RETINAL, Sodium pumping rhodopsin
Authors:Skopintsev, P, Ehrenberg, D, Weinert, T, James, D, Kar, R, Johnson, P, Ozerov, D, Furrer, A, Martiel, I, Dworkowski, F, Nass, K, Knopp, G, Cirelli, C, Gashi, D, Mous, S, Wranik, M, Gruhl, T, Kekilli, D, Bruenle, S, Deupi, X, Schertler, G.F.X, Benoit, R, Panneels, V, Nogly, P, Schapiro, I, Milne, C, Heberle, J, Standfuss, J.
Deposit date:2019-11-28
Release date:2020-05-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Femtosecond-to-millisecond structural changes in a light-driven sodium pump.
Nature, 583, 2020

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