3H8K
 
 | | Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution | | Descriptor: | Autocrine motility factor receptor, isoform 2, Ubiquitin-conjugating enzyme E2 G2 | | Authors: | Kalathur, R.C, Das, R, Li, J, Byrd, R.A, Ji, X. | | Deposit date: | 2009-04-29 | | Release date: | 2009-07-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
Mol.Cell, 34, 2009
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9DBQ
 | | Cryo-EM structure of human ABCB6 transporter in an inward-facing conformation | | Descriptor: | ATP-binding cassette sub-family B member 6, CHOLESTEROL HEMISUCCINATE | | Authors: | Shaik, M.M, Myasnikov, A, Oldham, M.L, Baril, S.A, Kalathur, R.C, Schuetz, J.D. | | Deposit date: | 2024-08-23 | | Release date: | 2024-11-20 | | Last modified: | 2024-12-04 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | The role of ATP-binding Cassette subfamily B member 6 in the inner ear.
Nat Commun, 15, 2024
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9B0L
 | | Cryo-EM structure of Acanthamoeba polyphaga mimivirus Fanzor2 ternary complex | | Descriptor: | DNA (5'-D(P*AP*GP*GP*AP*GP*GP*TP*GP*GP*CP*TP*GP*CP*CP*CP*CP*GP*AP*CP*CP*GP*TP*C)-3'), DNA (5'-D(P*CP*CP*CP*A)-3'), DNA (5'-D(P*GP*AP*CP*GP*GP*TP*CP*GP*GP*GP*C)-3'), ... | | Authors: | Qayyum, M.Z, Schargel, R.D, Tanwar, A.S, Kellogg, E.H, Kalathur, R.C. | | Deposit date: | 2024-03-12 | | Release date: | 2024-10-09 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Structure of Fanzor2 reveals insights into the evolution of the TnpB superfamily.
Nat.Struct.Mol.Biol., 32, 2025
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4WD7
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4WD8
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8UR8
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6D74
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9AXE
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8UR6
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8UR3
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8UM1
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8UM2
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4RYQ
 | | Crystal structure of BcTSPO, type 2 at 1.7 Angstrom | | Descriptor: | Integral membrane protein, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | | Authors: | Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2014-12-16 | | Release date: | 2015-01-28 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
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4RYM
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4RYR
 | | Crystal structure of BcTSPO, type 2 at 1.7 Angstrom with DMSO | | Descriptor: | DIMETHYL SULFOXIDE, Integral membrane protein, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | | Authors: | Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2014-12-16 | | Release date: | 2015-01-28 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.704 Å) | | Cite: | Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
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4RYJ
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4RYO
 | | Crystal structure of BcTSPO type II high resolution monomer | | Descriptor: | DIMETHYL SULFOXIDE, Integral membrane protein, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | | Authors: | Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2014-12-15 | | Release date: | 2015-04-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
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4RYI
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4RYN
 | | Crystal structure of BcTSPO, type1 monomer | | Descriptor: | CACODYLATE ION, DODECYL-ALPHA-D-MALTOSIDE, Integral membrane protein, ... | | Authors: | Guo, Y, Liu, Q, Hendrickson, W.A, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2014-12-15 | | Release date: | 2015-02-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Protein structure. Structure and activity of tryptophan-rich TSPO proteins.
Science, 347, 2015
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7LEW
 | | Crystal structure of UBE2G2 in complex with the UBE2G2-binding region of AUP1 | | Descriptor: | Lipid droplet-regulating VLDL assembly factor AUP1, Ubiquitin-conjugating enzyme E2 G2 | | Authors: | Liang, Y.-H, Smith, C.E, Tsai, Y.C, Weissman, A.M, Ji, X. | | Deposit date: | 2021-01-15 | | Release date: | 2021-11-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.736 Å) | | Cite: | A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation.
Plos Biol., 19, 2021
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7K0K
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound | | Descriptor: | 3-Dehydrosphinganine, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ... | | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | Deposit date: | 2020-09-04 | | Release date: | 2021-02-24 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0N
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, Serine palmitoyltransferase 1, ... | | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | Deposit date: | 2020-09-04 | | Release date: | 2021-02-24 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0O
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, Serine palmitoyltransferase 1, ... | | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | Deposit date: | 2020-09-04 | | Release date: | 2021-02-24 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0J
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Serine palmitoyltransferase 1, Serine palmitoyltransferase 2, ... | | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | Deposit date: | 2020-09-04 | | Release date: | 2021-02-24 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0Q
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound | | Descriptor: | Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | Deposit date: | 2020-09-04 | | Release date: | 2021-02-24 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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