1D31
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![BU of 1d31 by Molmil](/molmil-images/mine/1d31) | THE THREE-DIMENSIONAL STRUCTURES OF BULGE-CONTAINING DNA FRAGMENTS | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | Authors: | Joshua-Tor, L, Frolow, F, Appella, E, Hope, H, Rabinovich, D, Sussman, J.L. | Deposit date: | 1991-04-25 | Release date: | 1992-04-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Three-dimensional structures of bulge-containing DNA fragments. J.Mol.Biol., 225, 1992
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1GCB
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![BU of 1gcb by Molmil](/molmil-images/mine/1gcb) | GAL6, YEAST BLEOMYCIN HYDROLASE DNA-BINDING PROTEASE (THIOL) | Descriptor: | GAL6 HG (EMTS) DERIVATIVE, GLYCEROL, MERCURY (II) ION, ... | Authors: | Joshua-Tor, L, Xu, H.E, Johnston, S.A, Rees, D.C. | Deposit date: | 1995-07-18 | Release date: | 1995-10-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science, 269, 1995
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3GCB
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![BU of 3gcb by Molmil](/molmil-images/mine/3gcb) | GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454 | Descriptor: | GAL6, GLYCEROL, SULFATE ION | Authors: | Joshua-Tor, L, Zheng, W, Johnston, S.A. | Deposit date: | 1998-02-27 | Release date: | 1998-10-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
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1A6R
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![BU of 1a6r by Molmil](/molmil-images/mine/1a6r) | GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A | Descriptor: | GAL6, SULFATE ION | Authors: | Joshua-Tor, L, Zheng, W, Johnston, S.A. | Deposit date: | 1998-02-27 | Release date: | 1998-10-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
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7UX9
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![BU of 7ux9 by Molmil](/molmil-images/mine/7ux9) | Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA) | Descriptor: | ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... | Authors: | Ipsaro, J.J, Adams, D.W, Joshua-Tor, L. | Deposit date: | 2022-05-05 | Release date: | 2023-08-09 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation. Cell, 186, 2023
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6X46
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![BU of 6x46 by Molmil](/molmil-images/mine/6x46) | NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains) | Descriptor: | Gametocyte-specific factor 1, ZINC ION | Authors: | Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L. | Deposit date: | 2020-05-22 | Release date: | 2021-03-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. Cell Rep, 34, 2021
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1U04
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![BU of 1u04 by Molmil](/molmil-images/mine/1u04) | |
4KRE
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![BU of 4kre by Molmil](/molmil-images/mine/4kre) | |
4KRF
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![BU of 4krf by Molmil](/molmil-images/mine/4krf) | |
1R6Z
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![BU of 1r6z by Molmil](/molmil-images/mine/1r6z) | The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion) | Descriptor: | Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2003-10-17 | Release date: | 2004-01-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat.Struct.Biol., 10, 2003
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1R9W
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![BU of 1r9w by Molmil](/molmil-images/mine/1r9w) | |
4PMW
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![BU of 4pmw by Molmil](/molmil-images/mine/4pmw) | |
8E29
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![BU of 8e29 by Molmil](/molmil-images/mine/8e29) | |
8E27
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![BU of 8e27 by Molmil](/molmil-images/mine/8e27) | RNA-free Human Dis3L2 | Descriptor: | DIS3-like exonuclease 2 | Authors: | Meze, K, Thomas, D.R, Joshua-Tor, L. | Deposit date: | 2022-08-14 | Release date: | 2023-03-01 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | A shape-shifting nuclease unravels structured RNA. Nat.Struct.Mol.Biol., 30, 2023
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8E28
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![BU of 8e28 by Molmil](/molmil-images/mine/8e28) | |
8E2A
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![BU of 8e2a by Molmil](/molmil-images/mine/8e2a) | |
4O9D
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![BU of 4o9d by Molmil](/molmil-images/mine/4o9d) | Structure of Dos1 propeller | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Rik1-associated factor 1 | Authors: | Kuscu, C, Schalch, T, Joshua-Tor, L. | Deposit date: | 2014-01-02 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing. Proc.Natl.Acad.Sci.USA, 111, 2014
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3G7L
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![BU of 3g7l by Molmil](/molmil-images/mine/3g7l) | Chromodomain of Chp1 in complex with Histone H3K9me3 peptide | Descriptor: | ACETIC ACID, Chromo domain-containing protein 1, Histone H3.1/H3.2, ... | Authors: | Schalch, T, Joshua-Tor, L. | Deposit date: | 2009-02-10 | Release date: | 2009-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin Mol.Cell, 34, 2009
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3BTV
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![BU of 3btv by Molmil](/molmil-images/mine/3btv) | |
3BTS
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![BU of 3bts by Molmil](/molmil-images/mine/3bts) | |
3BTU
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![BU of 3btu by Molmil](/molmil-images/mine/3btu) | |
6OU9
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![BU of 6ou9 by Molmil](/molmil-images/mine/6ou9) | Asymmetric focused reconstruction of human norovirus GI.7 Houston strain VLP asymmetric unit in T=3 symmetry | Descriptor: | Major capsid protein | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | Deposit date: | 2019-05-04 | Release date: | 2019-06-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Proc.Natl.Acad.Sci.USA, 116, 2019
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6OUT
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![BU of 6out by Molmil](/molmil-images/mine/6out) | Asymmetric focused reconstruction of human norovirus GI.1 Norwalk strain VLP asymmetric unit in T=3 symmetry | Descriptor: | Capsid protein VP1 | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | Deposit date: | 2019-05-05 | Release date: | 2019-06-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Proc.Natl.Acad.Sci.USA, 116, 2019
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3V5R
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![BU of 3v5r by Molmil](/molmil-images/mine/3v5r) | Crystal structure of the unliganded form of Gal3p | Descriptor: | Protein GAL3, SULFATE ION | Authors: | Lavy, T, Kumar, P.R, He, H, Joshua-Tor, L. | Deposit date: | 2011-12-16 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation. Genes Dev., 26, 2012
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6OUC
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![BU of 6ouc by Molmil](/molmil-images/mine/6ouc) | Asymmetric focsued reconstruction of human norovirus GII.2 Snow Mountain Virus strain VLP asymmetric unit in T=1 symmetry | Descriptor: | Viral protein 1, ZINC ION | Authors: | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | Deposit date: | 2019-05-04 | Release date: | 2019-06-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Proc.Natl.Acad.Sci.USA, 116, 2019
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