8E29

Human Dis3L2 in complex with hairpin C-U12

Summary for 8E29

• Entry DOI: 10.2210/pdb8e29/pdb
• Related: 4PMW
• EMDB information: 27829
• Descriptor: DIS3-like exonuclease 2, RNA hairpin C-U12 (2 entities in total)
• Functional Keywords: 3'-5' exonuclease, ds-rna bound exonuclease, human exonuclease, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 109800.20

Authors

Meze, K.,Thomas, D.R.,Joshua-Tor, L. (deposition date: 2022-08-14, release date: 2023-03-01, Last modification date: 2023-03-29)

• Primary citation: Meze, K.,Axhemi, A.,Thomas, D.R.,Doymaz, A.,Joshua-Tor, L.; A shape-shifting nuclease unravels structured RNA.; Nat.Struct.Mol.Biol., 30:339-347, 2023; PubMed: 36823385; DOI: 10.1038/s41594-023-00923-x

Experimental method

ELECTRON MICROSCOPY (3.1 Å)