1U04

Crystal structure of full length Argonaute from Pyrococcus furiosus

Summary for 1U04

Descriptorhypothetical protein PF0537 (2 entities in total)
Functional Keywordsrnai, silencing, argonaute, piwi, paz, risc, slicer, rnase h, hydrolase-gene regulation complex, hydrolase/gene regulation
Biological sourcePyrococcus furiosus
Total number of polymer chains1
Total molecular weight91441.31
Authors
Song, J.J.,Smith, S.K.,Hannon, G.J.,Joshua-Tor, L. (deposition date: 2004-07-12, release date: 2004-08-17, Last modification date: 2011-07-13)
Primary citation
Song, J.J.,Smith, S.K.,Hannon, G.J.,Joshua-Tor, L.
Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity
Science, 305:1434-1437, 2004
PubMed: 15284453 (PDB entries with the same primary citation)
DOI: 10.1126
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.25 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.261181.9%4.0%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution