Crystal structure of full length Argonaute from Pyrococcus furiosus

Summary for 1U04

Descriptorhypothetical protein PF0537 (2 entities in total)
Functional Keywordsrnai, silencing, argonaute, piwi, paz, risc, slicer, rnase h, hydrolase-gene regulation complex, hydrolase/gene regulation
Biological sourcePyrococcus furiosus
Total number of polymer chains1
Total molecular weight91441.31
Song, J.J.,Smith, S.K.,Hannon, G.J.,Joshua-Tor, L. (deposition date: 2004-07-12, release date: 2004-08-17, Last modification date: 2011-07-13)
Primary citation
Song, J.J.,Smith, S.K.,Hannon, G.J.,Joshua-Tor, L.
Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity
Science, 305:1434-1437, 2004
PubMed: 15284453 (PDB entries with the same primary citation)
DOI: 10.1126
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.261181.9%4.0%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution