3KL4
| Recognition of a signal peptide by the signal recognition particle | 分子名称: | Signal peptide of yeast dipeptidyl aminopeptidase B, Signal recognition 54 kDa protein | 著者 | Janda, C.Y, Nagai, K, Li, J, Oubridge, C. | 登録日 | 2009-11-06 | 公開日 | 2010-03-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Recognition of a signal peptide by the signal recognition particle. Nature, 465, 2010
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4F0A
| Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-8, PALMITOLEIC ACID, ... | 著者 | Janda, C.Y, Waghray, D, Levin, A.M, Thomas, C, Garcia, K.C. | 登録日 | 2012-05-03 | 公開日 | 2012-06-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural basis of Wnt recognition by Frizzled. Science, 337, 2012
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5UN6
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5UN5
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8CTG
| Extracellular architecture of an engineered canonical Wnt signaling ternary complex | 分子名称: | Frizzled-8, Low-density lipoprotein receptor-related protein 6, PALMITOLEIC ACID, ... | 著者 | Tsutsumi, N, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-14 | 公開日 | 2023-03-15 | 最終更新日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Proc.Natl.Acad.Sci.USA, 120, 2023
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6WW2
| Structure of human Frizzled5 by fiducial-assisted cryo-EM | 分子名称: | Frizzled-5,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | 著者 | Tsutsumi, N, Jude, K.M, Gati, C, Garcia, K.C. | 登録日 | 2020-05-07 | 公開日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling. Elife, 9, 2020
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8FFE
| Crystal structure of LRP6 E1E2 domains bound to YW210.09 Fab and engineered XWnt8 peptide | 分子名称: | GLYCEROL, Low-density lipoprotein receptor-related protein 6, SODIUM ION, ... | 著者 | Jude, K.M, Tsutsumi, N, Waghray, D, Garcia, K.C. | 登録日 | 2022-12-08 | 公開日 | 2023-03-08 | 最終更新日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Proc.Natl.Acad.Sci.USA, 120, 2023
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6NDZ
| Designed repeat protein in complex with Fz8 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ACETIC ACID, ... | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | 登録日 | 2018-12-14 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.264 Å) | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019
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6NE2
| Designed repeat protein in complex with Fz7 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | 登録日 | 2018-12-15 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.299 Å) | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019
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6NE1
| Designed repeat protein in complex with Fz4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Pfs, ... | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | 登録日 | 2018-12-15 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.011 Å) | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019
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6NE4
| Designed repeat protein specifically in complex with Fz7CRD | 分子名称: | 1,2-ETHANEDIOL, Designed repeat binding protein, Frizzled-7, ... | 著者 | Miao, Y, Jude, K.M, Garcia, K.C. | 登録日 | 2018-12-16 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | 主引用文献 | Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019
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