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PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE IN COMPLEX WITH 3'-DEPHOSPHO-COA FROM ESCHERICHIA COLI
分子名称:	DEPHOSPHO COENZYME A, PROTEIN (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE), SULFATE ION
著者	Izard, T.
登録日	1999-01-18
公開日	2000-04-19
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity. EMBO J., 18, 1999

1B5S

DIHYDROLIPOYL TRANSACETYLASE (E.C.2.3.1.12) CATALYTIC DOMAIN (RESIDUES 184-425) FROM BACILLUS STEAROTHERMOPHILUS
分子名称:	DIHYDROLIPOAMIDE ACETYLTRANSFERASE
著者	Izard, T, Aevarsson, A, Allen, M.D, Westphal, A.H, Perham, R.N, De Kok, A, Hol, W.G.
登録日	1999-01-10
公開日	1999-02-16
最終更新日	2023-08-02
実験手法	X-RAY DIFFRACTION (4.4 Å)
主引用文献	Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes. Proc.Natl.Acad.Sci.USA, 96, 1999

2GWW

Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site (residues 602-633)
分子名称:	IpaA, vinculin
著者	Izard, T.
登録日	2006-05-07
公開日	2006-11-14
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.72 Å)
主引用文献	Shigella applies molecular mimicry to subvert vinculin and invade host cells. J.Cell Biol., 175, 2006

2HSQ

Human vinculin (head domain, Vh1, residues 1-258) in complex with Shigella's IpaA vinculin binding site 2 (residues 565-587)
分子名称:	Invasin ipaA, Vinculin
著者	Izard, T.
登録日	2006-07-22
公開日	2006-11-21
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (3.97 Å)
主引用文献	Shigella applies molecular mimicry to subvert vinculin and invade host cells. J.Cell Biol., 175, 2006

1GN8

PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE IN COMPLEX WITH Mn2+ATP FROM ESCHERICHIA COLI
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE, ...
著者	Izard, T.
登録日	2001-10-03
公開日	2002-01-17
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.83 Å)
主引用文献	The Crystal Structures of Phosphopantetheine Adenylyltransferase with Bound Substrates Reveal the Enzyme'S Catalytic Mechanism J.Mol.Biol., 315, 2001

1H1T

PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE IN COMPLEX WITH Coenzyme A FROM ESCHERICHIA COLI
分子名称:	4'-PHOSPHOPANTETHEINE, COENZYME A, PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE, ...
著者	Izard, T.
登録日	2002-07-21
公開日	2003-07-07
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.78 Å)
主引用文献	A Novel Adenylate Binding Site Confers Phosphopantetheine Adenylyltransferase Interactions with Coenzyme A J.Bacteriol., 185, 2003

1SYQ

Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636
分子名称:	Talin 1, vinculin isoform VCL
著者	Izard, T, Vonrhein, C.
登録日	2004-04-01
公開日	2004-07-20
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.42 Å)
主引用文献	Structural basis for amplifying vinculin activation by talin J.Biol.Chem., 279, 2004

1NAL

THE THREE-DIMENSIONAL STRUCTURE OF N-ACETYLNEURAMINATE LYASE FROM ESCHERICHIA COLI
分子名称:	N-ACETYLNEURAMINATE LYASE, SULFATE ION
著者	Izard, T, Lawrence, M.C, Malby, R.L, Lilley, G.G, Colman, P.M.
登録日	1994-02-28
公開日	1995-09-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	The three-dimensional structure of N-acetylneuraminate lyase from Escherichia coli. Structure, 2, 1994

1QHX

CHLORAMPHENICOL PHOSPHOTRANSFERASE IN COMPLEX WITH ATP FROM STREPTOMYCES VENEZUELAE
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (CHLORAMPHENICOL PHOSPHOTRANSFERASE)
著者	Izard, T.
登録日	1999-05-31
公開日	2000-06-01
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism Embo J., 19, 2000

1QJC

Phosphopantetheine Adenylyltransferase from Escherichia coli in complex with 4'-phosphopantetheine
分子名称:	4'-PHOSPHOPANTETHEINE, PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE, SULFATE ION
著者	Izard, T.
登録日	1999-06-23
公開日	2001-06-27
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.63 Å)
主引用文献	The Crystal Structures of Phosphopantetheine Adenylyltransferase with Bound Substrates Reveal the Enzyme'S Catalytic Mechanism J.Mol.Biol., 315, 2001

1QHN

CHLORAMPHENICOL PHOSPHOTRANSFERASE FROM STREPTOMYCES VENEZUELAE
分子名称:	CHLORAMPHENICOL PHOSPHOTRANSFERASE, SULFATE ION
著者	Izard, T.
登録日	1999-05-23
公開日	2000-06-07
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism Embo J., 19, 2000

1QHS

CHLORAMPHENICOL PHOSPHOTRANSFERASE IN COMPLEX WITH CHLORAMPHENICOL FROM STREPTOMYCES VENEZUELAE
分子名称:	CHLORAMPHENICOL, PROTEIN (CHLORAMPHENICOL PHOSPHOTRANSFERASE), SULFATE ION
著者	Izard, T.
登録日	1999-05-28
公開日	2000-06-01
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism Embo J., 19, 2000

1QHY

CHLORAMPHENICOL PHOSPHOTRANSFERASE FROM STREPTOMYCES VENEZUELAE IN COMPLEX WITH ATPGAMMAS AND CHLORAMPHENICOL
分子名称:	CHLORAMPHENICOL, CHLORAMPHENICOL PHOSPHOTRANSFERASE, MAGNESIUM ION, ...
著者	Izard, T.
登録日	1999-06-01
公開日	2000-06-07
最終更新日	2023-08-02
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism Embo J., 19, 2000

1RKC

Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)
分子名称:	Talin, Vinculin
著者	Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
登録日	2003-11-21
公開日	2004-01-13
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Vinculin activation by talin through helical bundle conversion Nature, 427, 2004

1RVG

crystal structure of class II fructose-bisphosphate aldolase from Thermus aquaticus in complex with Y
分子名称:	COBALT (II) ION, SODIUM ION, SULFATE ION, ...
著者	Izard, T, Sygusch, J.
登録日	2003-12-13
公開日	2004-01-27
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Induced Fit Movements and Metal Cofactor Selectivity of Class II Aldolases: STRUCTURE OF THERMUS AQUATICUS FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE. J.Biol.Chem., 279, 2004

1RKE

Human vinculin head (1-258) in complex with human vinculin tail (879-1066)
分子名称:	VCL protein, Vinculin
著者	Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R.
登録日	2003-11-21
公開日	2004-01-13
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Vinculin activation by talin through helical bundle conversion Nature, 427, 2004

1RV8

Class II fructose-1,6-bisphosphate aldolase from Thermus aquaticus in complex with cobalt
分子名称:	COBALT (II) ION, SODIUM ION, SULFATE ION, ...
著者	Izard, T, Sygusch, J.
登録日	2003-12-12
公開日	2004-01-27
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Induced Fit Movements and Metal Cofactor Selectivity of Class II Aldolases: STRUCTURE OF THERMUS AQUATICUS FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE. J.Biol.Chem., 279, 2004

1DXE

2-dehydro-3-deoxy-galactarate aldolase from Escherichia coli
分子名称:	2-DEHYDRO-3-DEOXY-GALACTARATE ALDOLASE, MAGNESIUM ION, PHOSPHATE ION
著者	Izard, T, Blackwell, N.C.
登録日	2000-01-03
公開日	2000-08-25
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Crystal Structures of the Metal-Dependent 2-Dehydro-3-Deoxy-Galactarate Aldolase Suggest a Novel Reaction Mechanism. Embo J., 19, 2000

1DXF

2-dehydro-3-deoxy-galactarate aldolase from Escherichia coli in complex with pyruvate
分子名称:	2-DEHYDRO-3-DEOXY-GALACTARATE ALDOLASE, MAGNESIUM ION, PYRUVIC ACID
著者	Izard, T, Blackwell, N.C.
登録日	2000-01-05
公開日	2000-08-25
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Crystal Structures of the Metal-Dependent 2-Dehydro-3-Deoxy-Galactarate Aldolase Suggest a Novel Reaction Mechanism. Embo J., 19, 2000

1GRQ

CHLORAMPHENICOL PHOSPHOTRANSFERASE IN COMPLEX WITH P-AMINO-CHLORAMPHENICOL FROM STREPTOMYCES VENEZUELAE
分子名称:	ALPHA-N-DICHLOROACETYL-P-AMINOPHENYLSERINOL, CHLORAMPHENICOL 3-O PHOSPHOTRANSFERASE, SULFATE ION
著者	Izard, T.
登録日	2001-12-15
公開日	2002-01-04
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structural Basis for Chloramphenicol Tolerance in Streptomyces Venezuelae by Chloramphenicol Phosphotransferase Activity Protein Sci., 10, 2001

1GRR

CHLORAMPHENICOL PHOSPHOTRANSFERASE IN COMPLEX WITH 2-Nac-CHLORAMPHENICOL FROM STREPTOMYCES VENEZUELAE
分子名称:	CHLORAMPHENICOL 3-O PHOSPHOTRANSFERASE, N-ACETYL-P-NITROPHENYLSERINOL, SULFATE ION
著者	Izard, T.
登録日	2001-12-15
公開日	2002-01-04
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structural Basis for Chloramphenicol Tolerance in Streptomyces Venezuelae by Chloramphenicol Phosphotransferase Activity Protein Sci., 10, 2001

6U4K

Human talin2 residues 1-403
分子名称:	Talin-2
著者	Izard, T, Rangarajan, E.S, Colgan, L, Yasuda, R, Chinthalapudi, K.
登録日	2019-08-26
公開日	2020-07-08
最終更新日	2020-09-23
実験手法	X-RAY DIFFRACTION (2.555 Å)
主引用文献	A distinct talin2 structure directs isoform specificity in cell adhesion. J.Biol.Chem., 295, 2020

4EHP

Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
分子名称:	ACETATE ION, Catenin alpha-1, Vinculin
著者	Izard, T, Rangarajan, E.S.
登録日	2012-04-03
公開日	2012-04-18
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.66 Å)
主引用文献	alpha-Catenin unfurls upon binding to vinculin J.Biol.Chem., 287, 2012

4IGG

Full-length human alpha-catenin crystal structure
分子名称:	Catenin alpha-1, PHOSPHATE ION
著者	Izard, T, Rangarajan, E.S.
登録日	2012-12-17
公開日	2012-12-26
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (3.66 Å)
主引用文献	Dimer asymmetry defines alpha-catenin interactions. Nat.Struct.Mol.Biol., 20, 2013

6MFS

Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)
分子名称:	PHOSPHATE ION, Talin-1 fusion, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者	Izard, T, Chinthalapudi, K, Rangarajan, E.S.
登録日	2018-09-12
公開日	2018-09-26
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.85 Å)
主引用文献	The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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