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4UU5
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BU of 4uu5 by Molmil
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE
Descriptor: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4UU6
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BU of 4uu6 by Molmil
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
7PAG
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BU of 7pag by Molmil
The pore conformation of lymphocyte perforin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Perforin-1
Authors:Ivanova, M.E, Lukoyanova, N, Malhotra, S, Topf, M, Trapani, J.A, Voskoboinik, I, Saibil, H.R.
Deposit date:2021-07-29
Release date:2022-02-16
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The pore conformation of lymphocyte perforin.
Sci Adv, 8, 2022
5LI9
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BU of 5li9 by Molmil
Structure of a nucleotide-bound form of PKCiota core kinase domain
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2016-07-14
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
7PT7
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BU of 7pt7 by Molmil
Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ADP:BeF3, state I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 7, ...
Authors:Saleh, A, Noguchi, Y, Aramayo, R, Ivanova, M.E, Speck, C.
Deposit date:2021-09-26
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer.
Nat Commun, 13, 2022
7PT6
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BU of 7pt6 by Molmil
Structure of MCM2-7 DH complexed with Cdc7-Dbf4 in the presence of ATPgS, state III
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 7, DDK kinase regulatory subunit DBF4, ...
Authors:Saleh, A, Noguchi, Y, Aramayo, R, Ivanova, M.E, Speck, C.
Deposit date:2021-09-26
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer.
Nat Commun, 13, 2022
5LIH
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BU of 5lih by Molmil
Structure of a peptide-substrate bound to PKCiota core kinase domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MANGANESE (II) ION, ...
Authors:Soriano, E.V, Purkiss, A.G, McDonald, N.Q.
Deposit date:2016-07-14
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
4C8H
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BU of 4c8h by Molmil
Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein.
Descriptor: CTF4
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase Alpha in the Eukaryotic Replisome
Nature, 510, 2014
4C93
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BU of 4c93 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha.
Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A, DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C95
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BU of 4c95 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA REPLICATION COMPLEX GINS PROTEIN SLD5
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C8S
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BU of 4c8s by Molmil
Crystal structure of the C-terminal region of yeast Ctf4
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
5LI1
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BU of 5li1 by Molmil
Structure of a Par3-inhibitory peptide bound to PKCiota core kinase domain
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Soriano, E.V, Purkiss, A.G, McDonald, N.Q.
Deposit date:2016-07-13
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
5HOI
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BU of 5hoi by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2.
Descriptor: DNA polymerase alpha-binding protein, Topoisomerase 1-associated factor 2
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5HOG
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BU of 5hog by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
Descriptor: DNA polymerase alpha-binding protein, Dna2p
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.092 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5NXQ
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BU of 5nxq by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP
Descriptor: DNA polymerase alpha-binding protein, GLYCEROL, MET-ASP-ILE-UA1-ILE-ASP-ASP-ILE-LEU-UA2-GLU-LEU-ASP-LYS-GLU
Authors:Wu, Y, Pellegrini, L.
Deposit date:2017-05-10
Release date:2017-08-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.
Angew. Chem. Int. Ed. Engl., 56, 2017

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