5LI1

Structure of a Par3-inhibitory peptide bound to PKCiota core kinase domain

Summary for 5LI1

• Entry DOI: 10.2210/pdb5li1/pdb
• Descriptor: Protein kinase C iota type, Par-3 partitioning defective 3 homolog (C. elegans), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (7 entities in total)
• Functional Keywords: apkc, polarity, complex, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : P41743
• Total number of polymer chains: 2
• Total formula weight: 43990.64

Authors

Soriano, E.V.,Purkiss, A.G.,McDonald, N.Q. (deposition date: 2016-07-13, release date: 2016-09-14, Last modification date: 2024-01-10)

• Primary citation: Soriano, E.V.,Ivanova, M.E.,Fletcher, G.,Riou, P.,Knowles, P.P.,Barnouin, K.,Purkiss, A.,Kostelecky, B.,Saiu, P.,Linch, M.,Elbediwy, A.,Kjr, S.,O'Reilly, N.,Snijders, A.P.,Parker, P.J.,Thompson, B.J.,McDonald, N.Q.; aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.; Dev.Cell, 38:384-398, 2016; PubMed: 27554858; DOI: 10.1016/j.devcel.2016.07.018

Experimental method

X-RAY DIFFRACTION (2 Å)