5LI1
Structure of a Par3-inhibitory peptide bound to PKCiota core kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein kinase C iota type | polymer | 354 | 40914.9 | 1 | UniProt (P41743) Pfam (PF00069) Pfam (PF00433) | Homo sapiens (Human) | Atypical protein kinase C-lambda/iota,aPKC-lambda/iota,nPKC-iota |
| 2 | B (B) | Par-3 partitioning defective 3 homolog (C. elegans) | polymer | 20 | 2389.7 | 1 | UniProt (Q28E03) | Xenopus tropicalis (Western clawed frog) | Uncharacterized protein |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 6 | F, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | H, I (A, B) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 248 - 596 (UniProt: P41743)
| PDB | External Database | Details |
|---|---|---|
| Gly 243 | - | expression tag |
| Pro 244 | - | expression tag |
| Leu 245 | - | expression tag |
| Ser 246 | - | expression tag |
| Phe 247 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43304.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 686.0 | |
| All* | Total formula weight | 43990.6 |
