4C93

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha.

Summary for 4C93

• Entry DOI: 10.2210/pdb4c93/pdb
• Related: 4C8H 4C8S
• Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A (3 entities in total)
• Functional Keywords: dna replication, adaptor protein, beta propeller domain
• Biological source: SACCHAROMYCES CEREVISIAE (YEAST); More
• Cellular location: Nucleus: Q01454 P13382
• Total number of polymer chains: 5
• Total formula weight: 166369.57

Authors

Simon, A.C.,Pellegrini, L. (deposition date: 2013-10-02, release date: 2014-04-30, Last modification date: 2014-06-18)

• Primary citation: Simon, A.C.,Zhou, J.C.,Perera, R.L.,Vandeursen, F.,Evrin, C.,Ivanova, M.E.,Kilkenny, M.L.,Renault, L.,Kjaer, S.,Matak-Vinkovic, D.,Labib, K.,Costa, A.,Pellegrini, L.; A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome; Nature, 510:293-, 2014; PubMed: 24805245; DOI: 10.1038/NATURE13234

Experimental method

X-RAY DIFFRACTION (2.694 Å)