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6X63
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BU of 6x63 by Molmil
Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR
分子名称: HIV-1 capsid protein
著者Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T.
登録日2020-05-27
公開日2020-09-02
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR.
Nat.Struct.Mol.Biol., 27, 2020
5FJB
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BU of 5fjb by Molmil
Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site
分子名称: GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P.
登録日2015-10-07
公開日2016-03-16
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site.
Nat.Commun., 7, 2016
3O1U
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BU of 3o1u by Molmil
Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*AP*AP*(MDV)P*AP*CP*CP*GP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
7CX3
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BU of 7cx3 by Molmil
Cryo-EM structure of the Taprenepag-bound EP2-Gs complex
分子名称: 2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y.
登録日2020-09-01
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
Sci Adv, 7, 2021
3O1O
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Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-21
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase
Nature, 468, 2010
7CX2
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Cryo-EM structure of the PGE2-bound EP2-Gs complex
分子名称: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y.
登録日2020-09-01
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
Sci Adv, 7, 2021
7CX4
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BU of 7cx4 by Molmil
Cryo-EM structure of the Evatanepag-bound EP2-Gs complex
分子名称: 2-[3-[[(4-~{tert}-butylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y.
登録日2020-09-01
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
Sci Adv, 7, 2021
3O1S
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Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*AP*AP*(MDQ)P*AP*CP*CP*GP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
3O1T
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BU of 3o1t by Molmil
Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*AP*AP*(MDU)P*AP*CP*CP*GP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
3O1M
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BU of 3o1m by Molmil
Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-21
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
3O1V
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BU of 3o1v by Molmil
Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*AP*AP*(MDJ)P*AP*CP*CP*GP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
3O1P
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BU of 3o1p by Molmil
Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-21
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
3O1R
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BU of 3o1r by Molmil
Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), ...
著者Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C.
登録日2010-07-21
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
2M02
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BU of 2m02 by Molmil
3D structure of cap-gly domain of mammalian dynactin determined by magic angle spinning NMR spectroscopy
分子名称: Dynactin subunit 1
著者Yan, S, Hou, G, Schwieters, C.D, Ahmed, S, Williams, J.C, Polenova, T.
登録日2012-10-15
公開日2013-05-08
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End-Binding Protein EB1.
J.Mol.Biol., 425, 2013
2MPX
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BU of 2mpx by Molmil
Three-dimensional structure of CAP-GLY DOMAIN ASSEMBLED ON MICROTUBULES DETERMINED BY MAS NMR SPECTROSCOPY
分子名称: Dynactin subunit 1
著者Yan, S, Hou, G, Zhang, H, Polenova, T, Williams, J.C.
登録日2014-06-08
公開日2015-11-11
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献THREE-DIMENSIONAL STRUCTURE of CAP-GLY DOMAIN ASSEMBLED ON MICROTUBULES DETERMINED BY MAS NMR SPECTROSCOPY
To be Published
6WAP
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BU of 6wap by Molmil
Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR
分子名称: HIV-1 capsid protein
著者Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T.
登録日2020-03-25
公開日2020-09-02
最終更新日2023-06-14
実験手法SOLID-STATE NMR
主引用文献Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR.
Nat.Struct.Mol.Biol., 27, 2020
5IMX
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BU of 5imx by Molmil
Anaplastic lymphoma kinase (ALK) catalytic domain complexed with novel inhibitor 3-sulfonylpyrazol-4-amino pyrimidine
分子名称: 5-chloro-N~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1H-pyrazol-4-yl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor
著者Wang, C, Zhang, P, Dong, J.
登録日2016-03-07
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5UPW
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BU of 5upw by Molmil
CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations
分子名称: Gag polyprotein
著者Perilla, J.R.
登録日2017-02-04
公開日2017-03-01
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations.
J Phys Chem B, 121, 2017
5UP4
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Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
分子名称: HIV-1 Capsid Protein and spacer peptide 1
著者Perilla, J.R, Schirra, R, Zhang, P, Schulten, K.
登録日2017-02-01
公開日2017-12-06
最終更新日2017-12-13
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Quenching protein dynamics interferes with HIV capsid maturation.
Nat Commun, 8, 2017

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