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5C7W
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BU of 5c7w by Molmil
5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.
分子名称: 5'-monophosphate Z:P guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE
著者Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A.
登録日2015-06-25
公開日2015-08-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
5C7U
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BU of 5c7u by Molmil
5'-monophosphate wt Guanine Riboswitch bound to hypoxanthine.
分子名称: 5'-monophosphate wt guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE
著者Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A.
登録日2015-06-24
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
6MIH
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BU of 6mih by Molmil
Crystal structure of host-guest complex with PC hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIG
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BU of 6mig by Molmil
Crystal structure of host-guest complex with PB hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), Gag-Pol polyprotein
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIK
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BU of 6mik by Molmil
Crystal structure of host-guest complex with PP hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6B1S
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BU of 6b1s by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*AP*(CGY)P*(CGY)P*TP*TP*TP*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
6B1Q
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BU of 6b1q by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(CJ1)P*(CJ1)P*(CJ1))-3'), DNA (5'-D(P*(1AP)P*(1AP)P*(1AP)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
6B1R
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BU of 6b1r by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(1WA))-3'), DNA (5'-D(P*(IGU)P*(IGU)P*(IGU)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
8TXO
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BU of 8txo by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Aiyer, S, Shan, Z, Oh, J, Wang, D, Tan, Y.Z, Lyumkis, D.
登録日2023-08-23
公開日2024-01-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Overcoming resolution attenuation during tilted cryo-EM data collection.
Nat Commun, 15, 2024
4RHD
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BU of 4rhd by Molmil
DNA Duplex with Novel ZP Base Pair
分子名称: DNA 9mer novel P nucleobase, DNA 9mer novel Z nucleobase, MAGNESIUM ION
著者Zhang, W, Zhang, L, Benner, S, Huang, Z.
登録日2014-10-01
公開日2015-07-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of functional six-nucleotide DNA.
J.Am.Chem.Soc., 137, 2015
5VBS
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BU of 5vbs by Molmil
Structural basis for a six letter alphabet including GATCKX
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(DX)P*(DX)P*T)-3'), DNA (5'-D(P*AP*(93D)P*(93D)P*AP*TP*AP*AP*G)-3'), reverse transcriptase catalytic fragment
著者Singh, I, Georgiadis, M.M.
登録日2017-03-30
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).
ACS Synth Biol, 6, 2017
5W6Q
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BU of 5w6q by Molmil
Structural basis for recognition of artificial DNA by an evolved KlenTaq variant
分子名称: DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(1W5))-3'), DNA (5'-D(P*GP*(1WA)P*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA polymerase I, ...
著者Singh, I, Georgiadis, M.M.
登録日2017-06-16
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.
Nucleic Acids Res., 46, 2018
5W6K
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BU of 5w6k by Molmil
Structure of mutant Taq Polymerase incorporating unnatural base pairs Z:P
分子名称: (1R)-1-[6-amino-5-(dihydroxyamino)-2-hydroxypyridin-3-yl]-1,4-anhydro-2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-erythro-pentitol, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(P*(1WA)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
著者Singh, I, Georgiadis, M.M.
登録日2017-06-16
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.339 Å)
主引用文献Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.
Nucleic Acids Res., 46, 2018
8CRZ
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BU of 8crz by Molmil
Crystal structure of alien DNA CTSZZPBSBSZPPBAG in a tetragonal lattice
分子名称: DNA (5'-D(*CP*TP*(JSP)P*(1W5)P*(1W5)P*(1WA)P*(IGU)P*(JSP))-3'), DNA (5'-D(P*(IGU)P*(JSP)P*(1W5)P*(1WA)P*(1WA)P*(IGU)P*AP*G)-3')
著者Georgiadis, M.M.
登録日2022-05-12
公開日2023-05-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Alien DNA visualized at high resolution in A- and B-forms
To Be Published
8CRY
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BU of 8cry by Molmil
Crystal structure of alien DNA CTSZZPBSBSZPPBAG in an orthorhombic lattice
分子名称: DNA (5'-D(*CP*TP*(JSP)P*(1W5)P*(1W5)P*(1WA)P*(IGU)P*(JSP)P*(IGU)P*(JSP)P*(1W5)P*(1WA)P*(1WA)P*(IGU)P*AP*G)-3'), MAGNESIUM ION
著者Georgiadis, M.M.
登録日2022-05-12
公開日2023-05-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Alien DNA visualized at high resolution in A- and B-forms
To Be Published
8CS0
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BU of 8cs0 by Molmil
Crystal structure of alien DNA CTSZZPBSBSZPPBAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase
分子名称: DNA (5'-D(*CP*TP*(JSP)P*(1W5)P*(1W5)P*(1WA)P*(IGU)P*(JSP))-3'), DNA (5'-D(P*(IGU)P*(JSP)P*(1W5)P*(1WA)P*(1WA)P*(IGU)P*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M.
登録日2022-05-12
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Alien DNA visualized at high resolution in A- and B-forms
To Be Published
8SY5
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BU of 8sy5 by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site
分子名称: 2-oxo-2-hydroadenosine 5'-(tetrahydrogen triphosphate), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Shan, Z, Lyumkis, D, Oh, J, Wang, D.
登録日2023-05-24
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
8SY6
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BU of 8sy6 by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Shan, Z, Lyumkis, D, Oh, J, Wang, D.
登録日2023-05-24
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
8SY7
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BU of 8sy7 by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Shan, Z, Lyumkis, D, Oh, J, Wang, D.
登録日2023-05-24
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
4XO0
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BU of 4xo0 by Molmil
Crystal structure of 5'-CTTATPPTAZZATAAG in a host-guest complex
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*T)-3'), DNA (5'-D(P*AP*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
4XPC
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BU of 4xpc by Molmil
Crystal structure of 5'- CTTATAAATTTATAAG in a host-guest complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*TP*AP*AP*G)-3'), ...
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
4XPE
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BU of 4xpe by Molmil
Crystal structure of 5'-CTTATGGGCCCATAAG in a host-guest complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*TP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*AP*AP*G)-3'), ...
著者Georgiadis, M.M, Singh, I.
登録日2015-01-16
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
4XNO
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BU of 4xno by Molmil
Crystal structure of 5'-CTTATPPPZZZATAAG
分子名称: DNA (5'-D(*CP*TP*(BRU)P*AP*TP*(1WA)P*(1WA)P*(1WA)P*(1W5)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3')
著者Georgiadis, M.M, Singh, I.
登録日2015-01-15
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.985 Å)
主引用文献Structural basis for a six nucleotide genetic alphabet.
J. Am. Chem. Soc., 137, 2015
7UYO
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BU of 7uyo by Molmil
Crystal structure of B-form alien DNA 5'-CTTSSPBZPSZBBAAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase
分子名称: DNA (5'-D(*CP*TP*TP*(JSP)P*(JSP)P*(1WA)P*(IGU)P*(1W5))-3'), DNA (5'-D(P*(1WA)P*(JSP)P*(1W5)P*(IGU)P*(IGU)P*AP*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M.
登録日2022-05-06
公開日2023-05-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of 'ALternative Isoinformational ENgineered' DNA in B-form.
Philos.Trans.R.Soc.Lond.B Biol.Sci., 378, 2023
7UYN
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BU of 7uyn by Molmil
Crystal structure of B-form alien DNA 5'-CTTBPPBBSSZZSAAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase
分子名称: DNA (5'-D(*CP*TP*TP*(IGU)P*(1WA)P*(1WA)P*(IGU)P*(IGU))-3'), DNA (5'-D(P*(JSP)P*(JSP)P*(1W5)P*(1W5)P*(JSP)P*AP*AP*G)-3'), reverse transcriptase
著者Georgiadis, M.M.
登録日2022-05-06
公開日2023-05-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of 'ALternative Isoinformational ENgineered' DNA in B-form.
Philos.Trans.R.Soc.Lond.B Biol.Sci., 378, 2023

 

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