8DW5
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![BU of 8dw5 by Molmil](/molmil-images/mine/8dw5) | Complex of Human Transthyretin with 3',5'-Dichlorophenylanthranilic Acid | Descriptor: | 2-[(3,5-dichlorophenyl)amino]benzoic acid, Transthyretin | Authors: | Truong, J.Q, Holdsworth, B, Holien, J.K. | Deposit date: | 2022-07-31 | Release date: | 2022-08-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural Analysis of the Complex of Human Transthyretin with 3',5'-Dichlorophenylanthranilic Acid at 1.5 angstrom Resolution. Molecules, 27, 2022
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4P8Q
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![BU of 4p8q by Molmil](/molmil-images/mine/4p8q) | Crystal Structure of Human Insulin Regulated Aminopeptidase with Alanine in Active Site | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucyl-cystinyl aminopeptidase, ... | Authors: | Hermans, S.J, Ascher, D.B, Hancock, N.C, Holien, J.K, Michell, B, Morton, C.J, Parker, M.W. | Deposit date: | 2014-03-31 | Release date: | 2014-12-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides. Protein Sci., 24, 2015
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4PJ6
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![BU of 4pj6 by Molmil](/molmil-images/mine/4pj6) | Crystal Structure of Human Insulin Regulated Aminopeptidase with Lysine in Active Site | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LYSINE, ... | Authors: | Hermans, S.J, Ascher, D.B, Hancock, N.C, Holien, J.K, Michell, B, Morton, C.J, Parker, M.W. | Deposit date: | 2014-05-12 | Release date: | 2014-12-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides. Protein Sci., 24, 2015
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3SL6
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![BU of 3sl6 by Molmil](/molmil-images/mine/3sl6) | Crystal structure of the catalytic domain of PDE4D2 with compound 12c | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... | Authors: | Feil, S.F. | Deposit date: | 2011-06-24 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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3SL4
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![BU of 3sl4 by Molmil](/molmil-images/mine/3sl4) | Crystal structure of the catalytic domain of PDE4D2 with compound 10D | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Feil, S.F. | Deposit date: | 2011-06-24 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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3SL8
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![BU of 3sl8 by Molmil](/molmil-images/mine/3sl8) | Crystal structure of the catalytic domain of PDE4D2 with compound 10o | Descriptor: | 1,2-ETHANEDIOL, 3-cyclopentyl 6-ethenyl 2-[(thiophen-2-ylacetyl)amino]-4,7-dihydrothieno[2,3-c]pyridine-3,6(5H)-dicarboxylate, DI(HYDROXYETHYL)ETHER, ... | Authors: | Feil, S.F. | Deposit date: | 2011-06-24 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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3SL5
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![BU of 3sl5 by Molmil](/molmil-images/mine/3sl5) | Crystal structure of the catalytic domain of PDE4D2 complexed with compound 10d | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... | Authors: | Feil, S.F. | Deposit date: | 2011-06-24 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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3SL3
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![BU of 3sl3 by Molmil](/molmil-images/mine/3sl3) | Crystal structure of the apo form of the catalytic domain of PDE4D2 | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Feil, S.F. | Deposit date: | 2011-06-24 | Release date: | 2011-10-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
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4OGB
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![BU of 4ogb by Molmil](/molmil-images/mine/4ogb) | Crystal structure of the catalytic domain of PDE4D2 with compound 2 | Descriptor: | (2R)-8-(3,4-dimethoxyphenyl)-6-methyl-2-(tetrahydro-2H-pyran-4-yl)-2H-chromen-4-ol, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Feil, S.C, Parker, M.W. | Deposit date: | 2014-01-15 | Release date: | 2015-01-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | The PDE inhibition profile of LY294002 and tetrahydropyranyl analogues reveals a chromone motif for the development of PDE inhibitors To be Published
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4GWJ
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![BU of 4gwj by Molmil](/molmil-images/mine/4gwj) | |
4GWI
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![BU of 4gwi by Molmil](/molmil-images/mine/4gwi) | |
3KMN
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![BU of 3kmn by Molmil](/molmil-images/mine/3kmn) | Crystal Structure of the Human Apo GST Pi C47S/Y108V Double Mutant | Descriptor: | CALCIUM ION, CARBONATE ION, Glutathione S-transferase P, ... | Authors: | Parker, L.J. | Deposit date: | 2009-11-11 | Release date: | 2010-03-23 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Diuretic drug binding to human glutathione transferase P1-1: potential role of CYS101 revealed in the double mutant C47S/Y108V to be published
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3KM6
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![BU of 3km6 by Molmil](/molmil-images/mine/3km6) | |
3KMO
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![BU of 3kmo by Molmil](/molmil-images/mine/3kmo) | |
3LEI
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![BU of 3lei by Molmil](/molmil-images/mine/3lei) | Lectin Domain of Lectinolysin complexed with Fucose | Descriptor: | CALCIUM ION, NICKEL (II) ION, Platelet aggregation factor Sm-hPAF, ... | Authors: | Feil, S.C. | Deposit date: | 2010-01-14 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure, 20, 2012
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3LE0
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![BU of 3le0 by Molmil](/molmil-images/mine/3le0) | Lectin Domain of Lectinolysin complexed with Glycerol | Descriptor: | CALCIUM ION, GLYCEROL, NICKEL (II) ION, ... | Authors: | Feil, S.C. | Deposit date: | 2010-01-13 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure, 20, 2012
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3LEG
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![BU of 3leg by Molmil](/molmil-images/mine/3leg) | Lectin Domain of Lectinolysin complexed with Lewis Y Antigen | Descriptor: | CALCIUM ION, NICKEL (II) ION, Platelet aggregation factor Sm-hPAF, ... | Authors: | Feil, S.C. | Deposit date: | 2010-01-14 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure, 20, 2012
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3LEK
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![BU of 3lek by Molmil](/molmil-images/mine/3lek) | Lectin Domain of Lectinolysin complexed with Lewis B Antigen | Descriptor: | CALCIUM ION, NICKEL (II) ION, Platelet aggregation factor Sm-hPAF, ... | Authors: | Feil, S.C. | Deposit date: | 2010-01-15 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. Structure, 20, 2012
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