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8SDU
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BU of 8sdu by Molmil
Structure of rat organic anion transporter 1 (OAT1)
Descriptor: Solute carrier family 22 member 6
Authors:Dou, T, Jiang, J.
Deposit date:2023-04-07
Release date:2023-10-18
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.05 Å)
Cite:The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.
Nat.Struct.Mol.Biol., 30, 2023
8SDZ
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BU of 8sdz by Molmil
Structure of rat organic anion transporter 1 (OAT1) in complex with probenecid
Descriptor: 4-(dipropylsulfamoyl)benzoic acid, Solute carrier family 22 member 6
Authors:Dou, T, Jiang, J.
Deposit date:2023-04-07
Release date:2023-10-18
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.
Nat.Struct.Mol.Biol., 30, 2023
8SDY
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BU of 8sdy by Molmil
Structure of rat organic anion transporter 1 (OAT1) in complex with para-aminohippuric acid (PAH)
Descriptor: N-(4-aminobenzoyl)glycine, Solute carrier family 22 member 6
Authors:Dou, T, Jiang, J.
Deposit date:2023-04-07
Release date:2023-10-18
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.
Nat.Struct.Mol.Biol., 30, 2023
6MNL
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BU of 6mnl by Molmil
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
Descriptor: Bromodomain-containing protein 4, FOXO3a peptide
Authors:Zeng, L, Zhou, M.-M.
Deposit date:2018-10-02
Release date:2018-10-31
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
8T53
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BU of 8t53 by Molmil
S. enterica WbaP in a styrene maleic acid liponanoparticle
Descriptor: Undecaprenyl-phosphate galactose phosphotransferase
Authors:Dodge, G.J, Imperiali, B.
Deposit date:2023-06-12
Release date:2024-02-14
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Mapping the architecture of the initiating phosphoglycosyl transferase from S. enterica O-antigen biosynthesis in a liponanoparticle.
Elife, 12, 2024
6JCS
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BU of 6jcs by Molmil
AAV5 in complex with AAVR
Descriptor: Capsid protein, Dyslexia-associated protein KIAA0319-like protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-08-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCR
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BU of 6jcr by Molmil
AAV1 in neutral condition at 3.07 Ang
Descriptor: Capsid protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-10-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCQ
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BU of 6jcq by Molmil
AAV1 in complex with AAVR
Descriptor: Capsid protein, Dyslexia-associated protein KIAA0319-like protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-10-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCT
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BU of 6jct by Molmil
AAV5 in neutral condition at 3.18 Ang
Descriptor: Capsid protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-07-31
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
2ETM
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BU of 2etm by Molmil
Crystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative
Descriptor: 7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE, Focal adhesion kinase 1
Authors:Lee, C.C.
Deposit date:2005-10-27
Release date:2006-10-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Focal Adhesion Kinase Domain Complexed with ATP and novel 7H-Pyrrolo [2,3-d] pyrimidine scaffolds
To be Published
2EY4
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BU of 2ey4 by Molmil
Crystal Structure of a Cbf5-Nop10-Gar1 Complex
Descriptor: Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ZINC ION, ...
Authors:Rashid, R, Liang, B, Li, H, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-11-09
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.
Mol.Cell, 21, 2006
7S4J
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BU of 7s4j by Molmil
CryoEM structure of Methylococcus capsulatus (Bath) pMMO in a native lipid nanodisc at 2.16 Angstrom resolution
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-09-09
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.16 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
7S4H
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BU of 7s4h by Molmil
CryoEM structure of Methylococcus capsulatus (Bath) pMMO in a native lipid nanodisc at 2.14 Angstrom resolution
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-09-08
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
7S4K
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BU of 7s4k by Molmil
CryoEM structure of Methylococcus capsulatus (Bath) pMMO in a native lipid nanodisc at 2.34 Angstrom resolution
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-09-09
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
7S4M
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BU of 7s4m by Molmil
CryoEM structure of Methylocystis sp. str. Rockwell pMMO in a POPC nanodisc at 2.42 Angstrom resolution
Descriptor: 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, subunit C family protein, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-09-09
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.42 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
7S4I
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BU of 7s4i by Molmil
CryoEM structure of Methylococcus capsulatus (Bath) pMMO in a native lipid nanodisc at 2.26 Angstrom resolution
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-09-09
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
7S4L
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BU of 7s4l by Molmil
CryoEM structure of Methylotuvimicrobium alcaliphilum 20Z pMMO in a POPC nanodisc at 2.46 Angstrom resolution
Descriptor: (S)-2,3-bis(hexanoyloxy)propyl(2-(trimethylammonio)ethyl)phosphate, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, COPPER (II) ION, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-09-09
Release date:2022-03-30
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
7T4O
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BU of 7t4o by Molmil
CryoEM structure of Methylococcus capsulatus (Bath) pMMO treated with potassium cyanide in a native lipid nanodisc at 3.65 Angstrom resolution
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ammonia monooxygenase/methane monooxygenase, subunit C family protein, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-12-10
Release date:2022-03-30
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
7T4P
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BU of 7t4p by Molmil
CryoEM structure of Methylococcus capsulatus (Bath) pMMO treated with potassium cyanide and copper in a native lipid nanodisc at 3.62 Angstrom resolution
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ...
Authors:Koo, C.W, Rosenzweig, A.C.
Deposit date:2021-12-10
Release date:2022-03-30
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
3VTP
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BU of 3vtp by Molmil
HIV fusion inhibitor MT-C34
Descriptor: Transmembrane protein gp41
Authors:Yao, X, Waltersperger, S, Wang, M, Cui, S.
Deposit date:2012-06-02
Release date:2012-08-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The M-T hook structure is critical for design of HIV-1 fusion inhibitors.
J.Biol.Chem., 287, 2012
3VGX
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BU of 3vgx by Molmil
Structure of gp41 T21/Cp621-652
Descriptor: ACETIC ACID, Envelope glycoprotein gp160, GLYCEROL
Authors:Yao, X, Waltersperger, S, Wang, M, Cui, S.
Deposit date:2011-08-22
Release date:2012-04-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.
J.Biol.Chem., 287, 2012
3VH7
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BU of 3vh7 by Molmil
Structure of HIV-1 gp41 NHR/fusion inhibitor complex P21
Descriptor: CP32M, Envelope glycoprotein gp160, MAGNESIUM ION
Authors:Yao, X, Waltersperger, S, Wang, M.T, Cui, S.
Deposit date:2011-08-23
Release date:2012-06-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.019 Å)
Cite:Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VGY
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BU of 3vgy by Molmil
Structure of HIV-1 gp41 NHR/fusion inhibitor complex P321
Descriptor: CP32M, Envelope glycoprotein gp160, SULFATE ION
Authors:Yao, X, Waltersperger, S, Wang, M.T, Cui, S.
Deposit date:2011-08-22
Release date:2012-06-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.034 Å)
Cite:Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VIE
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BU of 3vie by Molmil
HIV-gp41 fusion inhibitor Sifuvirtide
Descriptor: Envelope glycoprotein gp160, Sifuvirtide
Authors:Yao, X, Waltersperger, S, Wang, M.T, Cui, S.
Deposit date:2011-09-29
Release date:2012-01-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
J.Biol.Chem., 287, 2012
6LIT
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BU of 6lit by Molmil
Estrogen-related receptor beta(ERR2) in complex with BPA
Descriptor: 10-mer from Nuclear receptor coactivator 2, 4,4'-PROPANE-2,2-DIYLDIPHENOL, Steroid hormone receptor ERR2
Authors:Yao, B.Q, Li, Y.
Deposit date:2019-12-13
Release date:2020-10-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor beta.
J.Mol.Biol., 432, 2020

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數據於2024-05-15公開中

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