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7JW2
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BU of 7jw2 by Molmil
Crystal structure of Aedes aegypti Nibbler EXO domain
分子名称: Exonuclease mut-7 homolog
著者Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J.
登録日2020-08-24
公開日2021-01-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Proc.Natl.Acad.Sci.USA, 117, 2020
7JW3
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BU of 7jw3 by Molmil
Crystal structure of Aedes aegypti Nibbler NTD domain
分子名称: Exonuclease mut-7 homolog
著者Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J.
登録日2020-08-24
公開日2021-01-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Proc.Natl.Acad.Sci.USA, 117, 2020
7JW6
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BU of 7jw6 by Molmil
Crystal structure of Drosophila Nibbler EXO domain
分子名称: Exonuclease mut-7 homolog
著者Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J.
登録日2020-08-24
公開日2021-01-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Proc.Natl.Acad.Sci.USA, 117, 2020
3OQ5
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BU of 3oq5 by Molmil
Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with p53K382me1
分子名称: Cellular tumor antigen p53, Lethal(3)malignant brain tumor-like protein
著者Roy, S, West, L.E, Weiner, K.L, Hayashi, R, Shi, X, Appella, E, Gozani, O, Kutateladze, T.
登録日2010-09-02
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5005 Å)
主引用文献The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression.
J.Biol.Chem., 285, 2010
1EIC
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BU of 1eic by Molmil
CRYSTAL STRUCTURE OF F120A MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
分子名称: RIBONUCLEASE A
著者Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2000-02-25
公開日2002-02-13
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
1EIE
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BU of 1eie by Molmil
CRYSTAL STRUCTURE OF F120W MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
分子名称: RIBONUCLEASE A
著者Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2000-02-25
公開日2002-02-13
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
1FS3
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BU of 1fs3 by Molmil
CRYSTAL STRUCTURE OF WILD-TYPE BOVINE PANCREATIC RIBONUCLEASE A
分子名称: Ribonuclease A
著者Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2000-09-08
公開日2002-02-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
1EID
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BU of 1eid by Molmil
CRYSTAL STRUCTURE OF F120G MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A
分子名称: RIBONUCLEASE A
著者Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2000-02-25
公開日2002-02-13
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational strictness required for maximum activity and stability of bovine pancreatic ribonuclease A as revealed by crystallographic study of three Phe120 mutants at 1.4 A resolution.
Protein Sci., 11, 2002
1IZP
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BU of 1izp by Molmil
F46L mutant of bovine pancreatic ribonuclease A
分子名称: RIBONUCLEASE A
著者Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2002-10-11
公開日2003-11-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A
Biochemistry, 42, 2003
1IZQ
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F46V mutant of bovine pancreatic ribonuclease A
分子名称: RIBONUCLEASE A
著者Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2002-10-11
公開日2003-11-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A
Biochemistry, 42, 2003
1IZR
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BU of 1izr by Molmil
F46A mutant of bovine pancreatic ribonuclease A
分子名称: RIBONUCLEASE A
著者Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T.
登録日2002-10-11
公開日2003-11-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A
Biochemistry, 42, 2003
1WPX
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BU of 1wpx by Molmil
Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase Y, Carboxypeptidase Y inhibitor, ...
著者Mima, J, Hayashida, M, Fujii, T, Narita, Y, Hayashi, R, Ueda, M, Hata, Y.
登録日2004-09-14
公開日2005-03-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the carboxypeptidase y inhibitor i(c) in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction
J.Mol.Biol., 346, 2005
7YV1
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BU of 7yv1 by Molmil
Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab
分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ...
著者Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A.
登録日2022-08-18
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.454 Å)
主引用文献Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023
7YUZ
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BU of 7yuz by Molmil
Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784
分子名称: AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ...
著者Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T.
登録日2022-08-18
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.878 Å)
主引用文献Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023
2MWO
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BU of 2mwo by Molmil
Solution structure of 53BP1 tandem Tudor domains in complex with a p53K370me2 peptide
分子名称: Cellular tumor antigen p53, Tumor suppressor p53-binding protein 1
著者Cui, G, Botuyan, M.V, Mer, G.
登録日2014-11-15
公開日2014-12-10
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23, 2015
2MWP
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BU of 2mwp by Molmil
Solution structure of 53BP1 tandem Tudor domains in complex with a p53K382me2 peptide
分子名称: Cellular tumor antigen p53, Tumor suppressor p53-binding protein 1
著者Cui, G, Botuyan, M.V, Mer, G.
登録日2014-11-15
公開日2014-12-10
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1.
Structure, 23, 2015
7Q72
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BU of 7q72 by Molmil
Structure of Pla1 in complex with Red1
分子名称: NURS complex subunit red1, Poly(A) polymerase pla1
著者Soni, K, Wild, K, Sinning, I.
登録日2021-11-09
公開日2022-12-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
7Q73
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BU of 7q73 by Molmil
Structure of Pla1 apo
分子名称: GLYCEROL, Poly(A) polymerase pla1
著者Soni, K, Wild, K, Sinning, I.
登録日2021-11-09
公開日2022-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
7Q74
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BU of 7q74 by Molmil
Structure of Pla1 apo, with a C-terminal deletion
分子名称: Poly(A) polymerase pla1
著者Soni, K, Wild, K, Sinning, I.
登録日2021-11-09
公開日2022-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Nat Commun, 14, 2023
3LH0
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BU of 3lh0 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
分子名称: DIMETHYLATED p53 LYSINE 372 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-21
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGF
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BU of 3lgf by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K370me2
分子名称: DIMETHYLATED p53 Lysine 370 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-20
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
3LGL
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BU of 3lgl by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K382me2
分子名称: DIMETHYLATED p53 LYSINE 382 PEPTIDE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Roy, S, Kutateladze, T.G.
登録日2010-01-20
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.
J.Mol.Biol., 398, 2010
8JJS
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BU of 8jjs by Molmil
Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343
分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ...
著者Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T.
登録日2023-05-31
公開日2023-07-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.534 Å)
主引用文献Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor.
J.Am.Chem.Soc., 145, 2023
2K8F
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Structural Basis for the Regulation of p53 Function by p300
分子名称: Cellular tumor antigen p53, Histone acetyltransferase p300
著者Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E.
登録日2008-09-08
公開日2009-03-03
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation.
Structure, 17, 2009

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