6AKW
 
 | | Crystal structure of RNA dioxygenase bound with an inhibitor | | 分子名称: | 2-OXOGLUTARIC ACID, 2-[[2,6-bis(chloranyl)-4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO | | 著者 | Yang, C.-G, Huang, Y, Gan, J. | | 登録日 | 2018-09-04 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Cancer Cell, 35, 2019
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7D7L
 | | The crystal structure of SARS-CoV-2 papain-like protease in complex with YM155 | | 分子名称: | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione, CAFFEINE, GLYCEROL, ... | | 著者 | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | | 登録日 | 2020-10-04 | | 公開日 | 2021-04-21 | | 最終更新日 | 2021-11-17 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Protein Cell, 12, 2021
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7D7K
 | | The crystal structure of SARS-CoV-2 papain-like protease in apo form | | 分子名称: | 1,2-ETHANEDIOL, CAFFEINE, Non-structural protein 3, ... | | 著者 | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | | 登録日 | 2020-10-04 | | 公開日 | 2021-04-21 | | 最終更新日 | 2021-11-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Protein Cell, 12, 2021
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5UPB
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5B5T
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7X08
 | | S protein of SARS-CoV-2 in complex with 2G1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | 著者 | Guo, Y.Y, Zhang, Y.Y, Zhou, Q. | | 登録日 | 2022-02-21 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
Cell Discov, 8, 2022
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4TWD
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with memantine | | 分子名称: | Cys-loop ligand-gated ion channel, Memantine | | 著者 | Ulens, C, Spurny, R, Thompson, A.J, Alqazzaz, M, Debaveye, S, Lu, H, Price, K, Villalgordo, J.M, Tresadern, G, Lynch, J.W, Lummis, S.C.R. | | 登録日 | 2014-06-30 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.
Structure, 22, 2014
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7WJY
 | | Omicron spike trimer with 6m6 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-08 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
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7WJZ
 | | Omicron Spike bitrimer with 6m6 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-08 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
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7WK0
 | | Local refine of Omicron spike bitrimer with 6m6 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | | 登録日 | 2022-01-08 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-09-14 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
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7WL8
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7W8M
 | | Crystal structure of Co-type nitrile hydratase mutant from Pseudomonas thermophila - A129R | | 分子名称: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit beta, Nitrile hydratase | | 著者 | Ma, D, Cheng, Z.Y, Hou, X.D, Peplowski, L, Lai, Q.P, Fu, K, Yin, D.J, Rao, Y.J, Zhou, Z.M. | | 登録日 | 2021-12-08 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis.
Chem Sci, 13, 2022
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7W8L
 | | Crystal Structure of Co-type nitrile hydratase mutant from Pseudonocardia thermophila - M46R | | 分子名称: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit beta, Nitrile hydratase | | 著者 | Ma, D, Cheng, Z.Y, Hou, X.D, Peplowski, L, Lai, Q.P, Fu, K, Yin, D.J, Rao, Y.J, Zhou, Z.M. | | 登録日 | 2021-12-08 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis.
Chem Sci, 13, 2022
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7WL9
 | | Mouse Pendrin in chloride and bicarbonate in asymmetric state | | 分子名称: | CHLORIDE ION, Pendrin | | 著者 | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | | 登録日 | 2022-01-12 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
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7WL7
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7WK1
 | | Mouse Pendrin bound chloride in inward state | | 分子名称: | CHLORIDE ION, Pendrin | | 著者 | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | | 登録日 | 2022-01-08 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
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7WLA
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7WLE
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7WL2
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7WK7
 | | Mouse Pendrin bound bicarbonate in inward state | | 分子名称: | BICARBONATE ION, Pendrin | | 著者 | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | | 登録日 | 2022-01-08 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
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7WLB
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7EIV
 | | heterotetrameric glycyl-tRNA synthetase from Escherichia coli | | 分子名称: | GLYCINE, Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, ... | | 著者 | Ju, Y, Zhou, H. | | 登録日 | 2021-03-31 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications.
Nucleic Acids Res., 49, 2021
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7F02
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | 登録日 | 2021-06-03 | | 公開日 | 2022-11-09 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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7F04
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... | | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | 登録日 | 2021-06-03 | | 公開日 | 2022-11-09 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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7F03
 | | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | | 登録日 | 2021-06-03 | | 公開日 | 2022-11-09 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states.
Nat Commun, 13, 2022
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