7W8L

Crystal Structure of Co-type nitrile hydratase mutant from Pseudonocardia thermophila - M46R

Summary for 7W8L

Entry DOI	10.2210/pdb7w8l/pdb
Descriptor	Cobalt-containing nitrile hydratase subunit beta, Nitrile hydratase, COBALT (II) ION, ... (4 entities in total)
Functional Keywords	hydration, catalyze the hydration of nitriles to form amides, lyase
Biological source	Pseudonocardia thermophila DSM 43832 More
Total number of polymer chains	2
Total formula weight	49959.25
Authors	Ma, D.,Cheng, Z.Y.,Hou, X.D.,Peplowski, L.,Lai, Q.P.,Fu, K.,Yin, D.J.,Rao, Y.J.,Zhou, Z.M. (deposition date: 2021-12-08, release date: 2022-08-24, Last modification date: 2023-11-29)
Primary citation	Ma, D.,Cheng, Z.,Peplowski, L.,Han, L.,Xia, Y.,Hou, X.,Guo, J.,Yin, D.,Rao, Y.,Zhou, Z. Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis. Chem Sci, 13:8417-8428, 2022 Cited by PubMed: 35919716 DOI: 10.1039/d2sc02319a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.301 Å)

Structure validation