7W8M

Crystal structure of Co-type nitrile hydratase mutant from Pseudomonas thermophila - A129R

Summary for 7W8M

Entry DOI	10.2210/pdb7w8m/pdb
Descriptor	Nitrile hydratase, Cobalt-containing nitrile hydratase subunit beta, COBALT (II) ION, ... (4 entities in total)
Functional Keywords	hydratase, catalyze the hydration of nitriles to form amides, lyase
Biological source	Pseudonocardia thermophila DSM 43832 More
Total number of polymer chains	2
Total formula weight	50019.36
Authors	Ma, D.,Cheng, Z.Y.,Hou, X.D.,Peplowski, L.,Lai, Q.P.,Fu, K.,Yin, D.J.,Rao, Y.J.,Zhou, Z.M. (deposition date: 2021-12-08, release date: 2022-08-24, Last modification date: 2023-11-29)
Primary citation	Ma, D.,Cheng, Z.,Peplowski, L.,Han, L.,Xia, Y.,Hou, X.,Guo, J.,Yin, D.,Rao, Y.,Zhou, Z. Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis. Chem Sci, 13:8417-8428, 2022 Cited by PubMed: 35919716 DOI: 10.1039/d2sc02319a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation