1L4Y
 
 | | CRYSTAL STRUCTURE OF SHIKIMATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MGADP AT 2.0 ANGSTROM RESOLUTION | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Gu, Y, Reshetnikova, L, Li, Y, Wu, Y, Yan, H, Singh, S, Ji, X. | | 登録日 | 2002-03-06 | | 公開日 | 2002-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.
J.Mol.Biol., 319, 2002
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6VK9
 | | Cryo-EM structure of PilA-N/C from Geobacter sulfurreducens | | 分子名称: | Geopilin domain 1 protein, Geopilin domain 2 protein | | 著者 | Gu, Y, Srikanth, V, Malvankar, N.S, Samatey, F.A. | | 登録日 | 2020-01-19 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of Geobacter pili reveals secretory rather than nanowire behaviour
Nature, 597, 2021
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7LQ5
 | | Cryo-EM structure of OmcZ nanowire from Geobacter sulfurreducens | | 分子名称: | Cytochrome c, HEME C | | 著者 | Gu, Y, Srikanth, V, Malvankar, N.S, Samatey, F.A. | | 登録日 | 2021-02-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of Geobacter cytochrome OmcZ identifies mechanism of nanowire assembly and conductivity.
Nat Microbiol, 8, 2023
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5D0Q
 | | BamACDE complex, outer membrane beta-barrel assembly machinery (BAM) complex | | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamC, Outer membrane protein assembly factor BamD, ... | | 著者 | Gu, Y, Paterson, N, Zeng, Y, Dong, H, Wang, W, Dong, C. | | 登録日 | 2015-08-03 | | 公開日 | 2016-03-09 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of outer membrane protein insertion by the BAM complex.
Nature, 531, 2016
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5D0O
 | | BamABCDE complex, outer membrane beta barrel assembly machinery entire complex | | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | 著者 | Gu, Y, Paterson, N, Zeng, Y, Dong, H, Wang, W, Dong, C. | | 登録日 | 2015-08-03 | | 公開日 | 2016-03-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of outer membrane protein insertion by the BAM complex.
Nature, 531, 2016
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1L4U
 | | CRYSTAL STRUCTURE OF SHIKIMATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MGADP AND PT(II) AT 1.8 ANGSTROM RESOLUTION | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Gu, Y, Reshetnikova, L, Li, Y, Wu, Y, Yan, H, Singh, S, Ji, X. | | 登録日 | 2002-03-05 | | 公開日 | 2002-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.
J.Mol.Biol., 319, 2002
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1ML6
 | | Crystal Structure of mGSTA2-2 in Complex with the Glutathione Conjugate of Benzo[a]pyrene-7(R),8(S)-Diol-9(S),10(R)-Epoxide | | 分子名称: | 2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7,8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID, Glutathione S-Transferase GT41A, ISOPROPYL ALCOHOL | | 著者 | Gu, Y, Xiao, B, Wargo, H.L, Bucher, M.H, Singh, S.V, Ji, X. | | 登録日 | 2002-08-30 | | 公開日 | 2003-04-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward
benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide
Biochemistry, 42, 2003
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1F3B
 | | CRYSTAL STRUCTURE OF MGSTA1-1 IN COMPLEX WITH GLUTATHIONE CONJUGATE OF BENZO[A]PYRENE EPOXIDE | | 分子名称: | 2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7,8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID, GLUTATHIONE S-TRANSFERASE YA CHAIN | | 著者 | Gu, Y, Singh, S.V, Ji, X. | | 登録日 | 2000-06-01 | | 公開日 | 2000-10-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Residue R216 and catalytic efficiency of a murine class alpha glutathione S-transferase toward benzo[a]pyrene 7(R),8(S)-diol 9(S), 10(R)-epoxide.
Biochemistry, 39, 2000
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1F3A
 | | CRYSTAL STRUCTURE OF MGSTA1-1 IN COMPLEX WITH GSH | | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE YA CHAIN | | 著者 | Gu, Y, Singh, S.V, Ji, X. | | 登録日 | 2000-06-01 | | 公開日 | 2000-10-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Residue R216 and catalytic efficiency of a murine class alpha glutathione S-transferase toward benzo[a]pyrene 7(R),8(S)-diol 9(S), 10(R)-epoxide.
Biochemistry, 39, 2000
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1TDI
 | | Crystal Structure of hGSTA3-3 in Complex with Glutathione | | 分子名称: | GLUTATHIONE, Glutathione S-transferase A3-3 | | 著者 | Gu, Y, Guo, J, Pal, A, Pan, S.S, Zimniak, P, Singh, S.V, Ji, X. | | 登録日 | 2004-05-22 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.
Biochemistry, 43, 2004
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3VRL
 | | Crystal structure of BMJ4 p24 capsid protein in complex with A10F9 Fab | | 分子名称: | A10F9 Fab heavy chain, A10F9 Fab light chain, Gag protein | | 著者 | Gu, Y, Cao, F, Li, S, Yuan, Y.A, Xia, N. | | 登録日 | 2012-04-12 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of the HIV-1 capsid protein p24 in complex with the broad-spectrum antibody A10F9
To be Published
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7DWM
 | | Crystal structure of the phage VqmA-DPO complex | | 分子名称: | 3,5-dimethylpyrazin-2-ol, Transcriptional regulator | | 著者 | Gu, Y, Yang, W.S. | | 登録日 | 2021-01-17 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Understanding the mechanism of asymmetric gene regulation determined by the VqmA of vibriophage.
Biochem.Biophys.Res.Commun., 558, 2021
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5OR1
 | | BamA structure of Salmonella enterica | | 分子名称: | Outer membrane protein assembly factor BamA | | 著者 | Dong, C, Gu, Y. | | 登録日 | 2017-08-14 | | 公開日 | 2018-02-14 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | BamA beta 16C strand and periplasmic turns are critical for outer membrane protein insertion and assembly.
Biochem. J., 474, 2017
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7TO3
 | | Structure of Enterobacter cloacae Cap2-CdnD02 2:2 complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Gu, Y, Ye, Q, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | | 登録日 | 2022-01-22 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
Nature, 616, 2023
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8CWW
 | | Structure of S. cerevisiae Hop1 CBR bound to a nucleosome | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D. | | 登録日 | 2022-05-19 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
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8CZE
 | | Structure of a Xenopus Nucleosome with Widom 601 DNA | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D. | | 登録日 | 2022-05-24 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
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6ID4
 | | Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01 | | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Lescar, J, Wong, Y.H, Liew, C.W, Gu, Y, MacAry, P.A. | | 登録日 | 2018-09-08 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.
Nat Commun, 10, 2019
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7TQD
 | | Structure of Enterobacter cloacae Cap2-CdnD02 2:1 complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Gu, Y, Ye, Q, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. | | 登録日 | 2022-01-26 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-04-26 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | An E1-E2 fusion protein primes antiviral immune signalling in bacteria.
Nature, 616, 2023
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6EF8
 | | Cryo-EM of the OmcS nanowires from Geobacter sulfurreducens | | 分子名称: | C-type cytochrome OmcS, HEME C | | 著者 | Wang, F, Gu, Y, Egelman, E.H, Malvankar, N.S. | | 登録日 | 2018-08-16 | | 公開日 | 2019-04-10 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of Microbial Nanowires Reveals Stacked Hemes that Transport Electrons over Micrometers.
Cell, 177, 2019
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1RHH
 | | Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution | | 分子名称: | Fab X5, heavy chain, light chain | | 著者 | Darbha, R, Phogat, S, Labrijn, A.F, Shu, Y, Gu, Y, Andrykovitch, M, Zhang, M.Y, Pantophlet, R, Martin, L, Vita, C, Burton, D.R, Dimitrov, D.S, Ji, X. | | 登録日 | 2003-11-14 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope
Biochemistry, 43, 2004
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2QU6
 | | Crystal structure of the VEGFR2 kinase domain in complex with a benzoxazole inhibitor | | 分子名称: | 4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-N-methylpyridine-2-carboxamide, SULFATE ION, Vascular endothelial growth factor receptor 2 | | 著者 | Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H. | | 登録日 | 2007-08-03 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors.
J.Med.Chem., 50, 2007
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2QU5
 | | Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor | | 分子名称: | 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide, Vascular endothelial growth factor receptor 2 | | 著者 | Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H. | | 登録日 | 2007-08-03 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors.
J.Med.Chem., 50, 2007
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1YY7
 | | Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated transcription factor | | 分子名称: | CITRIC ACID, stringent starvation protein A | | 著者 | Hansen, A.-M, Gu, Y, Li, M, Andrykovitch, M, Waugh, D.S, Jin, D.J, Ji, X. | | 登録日 | 2005-02-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis for the function of stringent starvation protein A as a transcription factor
J.Biol.Chem., 280, 2005
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2G1J
 | | Crystal structure of Mycobacterium tuberculosis Shikimate Kinase at 2.0 angstrom resolution | | 分子名称: | SULFATE ION, Shikimate kinase | | 著者 | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | | 登録日 | 2006-02-14 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue.
Biochemistry, 45, 2006
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7TIL
 | | CryoEM structure of JetD from Pseudomonas aeruginosa | | 分子名称: | JetD | | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | | 登録日 | 2022-01-13 | | 公開日 | 2022-10-05 | | 最終更新日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA.
Mol.Cell, 82, 2022
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