Search by PDB author

Crystal structure of the ATP-gated P2X4 ion channel in the ATP-bound, open state at 2.8 Angstroms
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ...
Authors:	Hattori, M, Gouaux, E.
Deposit date:	2012-02-24
Release date:	2012-04-25
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature, 485, 2012

1FTJ

CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH GLUTAMATE AT 1.9 RESOLUTION
Descriptor:	GLUTAMATE RECEPTOR SUBUNIT 2, GLUTAMIC ACID, ZINC ION
Authors:	Armstrong, N, Gouaux, E.
Deposit date:	2000-09-12
Release date:	2000-11-01
Last modified:	2018-01-31
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron, 28, 2000

1FW0

CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH KAINATE AT 2.0 A RESOLUTION
Descriptor:	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR SUBUNIT 2
Authors:	Armstrong, N, Gouaux, E.
Deposit date:	2000-09-20
Release date:	2000-11-15
Last modified:	2017-08-02
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron, 28, 2000

1FTO

CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN THE APO STATE AT 2.0 A RESOLUTION
Descriptor:	GLUTAMATE RECEPTOR SUBUNIT 2
Authors:	Armstrong, N, Gouaux, E.
Deposit date:	2000-09-12
Release date:	2000-11-01
Last modified:	2017-08-02
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron, 28, 2000

1FTL

CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH THE ANTAGONIST DNQX AT 1.8 A RESOLUTION
Descriptor:	6,7-DINITROQUINOXALINE-2,3-DIONE, GLUTAMATE RECEPTOR SUBUNIT 2, SULFATE ION
Authors:	Armstrong, N, Gouaux, E.
Deposit date:	2000-09-12
Release date:	2000-11-01
Last modified:	2017-08-02
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron, 28, 2000

7LH3

Structure of human prestin in the presence of sodium sulfate
Descriptor:	Prestin
Authors:	Ge, J, Gouaux, E.
Deposit date:	2021-01-21
Release date:	2021-08-25
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (4.3 Å)
Cite:	Molecular mechanism of prestin electromotive signal amplification. Cell, 184, 2021

7LGW

Structure of human Prestin in nanodisc in the presence of NaCl
Descriptor:	CHLORIDE ION, CHOLESTEROL, DECANE, ...
Authors:	Ge, J, Gouaux, E.
Deposit date:	2021-01-21
Release date:	2021-08-25
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	Molecular mechanism of prestin electromotive signal amplification. Cell, 184, 2021

7LGU

Structure of human prestin in the presence of NaCl
Descriptor:	CHLORIDE ION, CHOLESTEROL, DECANE, ...
Authors:	Ge, J, Gouaux, E.
Deposit date:	2021-01-21
Release date:	2021-08-25
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (2.3 Å)
Cite:	Molecular mechanism of prestin electromotive signal amplification. Cell, 184, 2021

7LH2

Structure of human prestin in the presence of sodium salicylate and sodium sulfate
Descriptor:	2-HYDROXYBENZOIC ACID, CHOLESTEROL, Prestin
Authors:	Ge, J, Gouaux, E.
Deposit date:	2021-01-21
Release date:	2021-08-25
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (3.43 Å)
Cite:	Molecular mechanism of prestin electromotive signal amplification. Cell, 184, 2021

4FXZ

Crystal structure of LeuT-F253A bound to L-leucine from lipid bicelles
Descriptor:	ACETATE ION, LEUCINE, SODIUM ION, ...
Authors:	Wang, H, Gouaux, E.
Deposit date:	2012-07-03
Release date:	2012-08-08
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.601 Å)
Cite:	Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue. Embo Rep., 13, 2012

4FY0

Crystal structure of LeuT-F253A bound to L-selenomethionine from lipid bicelles
Descriptor:	SELENOMETHIONINE, SODIUM ION, Transporter
Authors:	Wang, H, Gouaux, E.
Deposit date:	2012-07-03
Release date:	2012-08-08
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue. Embo Rep., 13, 2012

4FZ1

Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at high pH
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Pi-theraphotoxin-Pc1a
Authors:	Baconguis, I, Gouaux, E.
Deposit date:	2012-07-05
Release date:	2012-08-01
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (3.359 Å)
Cite:	Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes. Nature, 489, 2012

4FZ0

Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at low pH
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, CHLORIDE ION, ...
Authors:	Baconguis, I, Gouaux, E.
Deposit date:	2012-07-05
Release date:	2012-08-01
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes. Nature, 489, 2012

1IIT

GLUR0 LIGAND BINDING CORE COMPLEX WITH L-SERINE
Descriptor:	SERINE, Slr1257 protein
Authors:	Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:	2001-04-24
Release date:	2001-09-19
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. J.Mol.Biol., 311, 2001

6AWQ

Anomalous chloride signal reveals the position of sertraline complexed with the serotonin transporter at the central site
Descriptor:	(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody FAB heavy chain, ...
Authors:	Coleman, J.A, Gouaux, E.
Deposit date:	2017-09-06
Release date:	2017-10-25
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (4.046 Å)
Cite:	Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol., 25, 2018

1II5

CRYSTAL STRUCTURE OF THE GLUR0 LIGAND BINDING CORE COMPLEX WITH L-GLUTAMATE
Descriptor:	GLUTAMIC ACID, Slr1257 protein
Authors:	Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:	2001-04-20
Release date:	2001-09-19
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. J.Mol.Biol., 311, 2001

6AVE

Structure of an acid sensing ion channel in a resting state at high pH
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1
Authors:	Yoder, N, Yoshioka, C, Gouaux, E.
Deposit date:	2017-09-02
Release date:	2018-03-21
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.7 Å)
Cite:	Gating mechanisms of acid-sensing ion channels. Nature, 555, 2018

1IIW

GLUR0 LIGAND BINDING CORE: CLOSED-CLEFT LIGAND-FREE STRUCTURE
Descriptor:	Slr1257 protein
Authors:	Mayer, M.L, Olson, R, Gouaux, E.
Deposit date:	2001-04-24
Release date:	2001-09-19
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. J.Mol.Biol., 311, 2001

6AWN

X-ray structure of the S439T human serotonin transporter complexed with paroxetine at the central site
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody FAB heavy chain, 8B6 antibody FAB light chain, ...
Authors:	Coleman, J.A, Gouaux, E.
Deposit date:	2017-09-06
Release date:	2017-10-25
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.62 Å)
Cite:	Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol., 25, 2018

6AWP

X-ray structure of the ts3 human serotonin transporter complexed with fluvoxamine at the central site
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody FAB heavy chain, 8B6 antibody FAB light chain, ...
Authors:	Coleman, J.A, Gouaux, E.
Deposit date:	2017-09-06
Release date:	2017-10-25
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.8 Å)
Cite:	Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol., 25, 2018

6AWO

X-ray structure of the ts3 human serotonin transporter complexed with sertraline at the central site
Descriptor:	(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody FAB heavy chain, ...
Authors:	Coleman, J.A, Gouaux, E.
Deposit date:	2017-09-06
Release date:	2017-10-25
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (3.534 Å)
Cite:	Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol., 25, 2018

1N0T

X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution.
Descriptor:	(S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID, ACETATE ION, Glutamate receptor 2, ...
Authors:	Hogner, A, Greenwood, J.R, Liljefors, T, Lunn, M.-L, Egebjerg, J, Larsen, I.K, Gouaux, E, Kastrup, J.S.
Deposit date:	2002-10-15
Release date:	2003-03-04
Last modified:	2017-08-16
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX. J.Med.Chem., 46, 2003

4XP4

X-ray structure of Drosophila dopamine transporter in complex with cocaine
Descriptor:	1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ANTIBODY FRAGMENT HEAVY CHAIN-PROTEIN, 9D5-HEAVY CHAIN, ...
Authors:	Aravind, P, Wang, K, Gouaux, E.
Deposit date:	2015-01-16
Release date:	2015-05-06
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015

4XNU

X-ray structure of Drosophila dopamine transporter in complex with nisoxetine
Descriptor:	CHLORIDE ION, CHOLESTEROL, Integral membrane protein-dopamine transporter, ...
Authors:	Aravind, P, Wang, K, Gouaux, E.
Deposit date:	2015-01-16
Release date:	2015-05-13
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.98 Å)
Cite:	X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat.Struct.Mol.Biol., 22, 2015

4XPF

X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to RTI-55
Descriptor:	1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ANTIBODY FRAGMENT HEAVY CHAIN-PROTEIN, 9D5-HEAVY CHAIN, ...
Authors:	Penmatsa, A, Wang, K.H, Gouaux, E.
Deposit date:	2015-01-16
Release date:	2015-05-06
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3.273 Å)
Cite:	Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521, 2015

<1 2 345 6 7 8 9 10 11 12 13 14 >

Total results:	340
Displayed results:	25
Sorted by:	Hit score (from highest)