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1PY4
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Beta2 microglobulin mutant H31Y displays hints for amyloid formations
分子名称: Beta-2-microglobulin precursor
著者Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M.
登録日2003-07-08
公開日2004-05-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation
J.Mol.Biol., 335, 2004
1JNJ
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BU of 1jnj by Molmil
NMR solution structure of the human beta2-microglobulin
分子名称: beta2-microglobulin
著者Verdone, G, Corazza, A, Viglino, P, Pettirossi, F, Giorgetti, S, Mangione, P, Andreola, A, Stoppini, M, Bellotti, V, Esposito, G.
登録日2001-07-24
公開日2002-02-27
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002
3DHJ
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BU of 3dhj by Molmil
Beta 2 microglobulin mutant W60C
分子名称: Beta-2-microglobulin
著者Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V.
登録日2008-06-18
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献DE loop mutations affect beta2-microglobulin stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 377, 2008
3DHM
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BU of 3dhm by Molmil
Beta 2 microglobulin mutant D59P
分子名称: Beta-2-microglobulin
著者Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V.
登録日2008-06-18
公開日2008-11-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DE loop mutations affect beta2-microglobulin stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 377, 2008
2VB5
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BU of 2vb5 by Molmil
Solution structure of W60G mutant of human beta2-microglobulin
分子名称: BETA-2-MICROGLOBULIN
著者Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V.
登録日2007-09-06
公開日2007-09-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties.
J.Mol.Biol., 378, 2008
2Z9T
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BU of 2z9t by Molmil
Crystal structure of the human beta-2 microglobulin mutant W60G
分子名称: Beta-2-microglobulin
著者Ricagno, S, Bolognesi, M, Bellotti, V, Corazza, A, Rennella, E, Gural, D, Mimmi, M.C, Betto, E, Pucillo, C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M.
登録日2007-09-26
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties
J.Mol.Biol., 378, 2008
4L3C
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BU of 4l3c by Molmil
Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
登録日2013-06-05
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4L29
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Structure of wtMHC class I with NY-ESO1 double mutant
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
登録日2013-06-04
公開日2013-12-25
最終更新日2014-02-26
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
3NA4
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D53P beta-2 microglobulin mutant
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin
著者Azinas, S, Ricagno, S, Bolognesi, M.
登録日2010-06-01
公開日2011-06-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献D-strand perturbation and amyloid propensity in beta-2 microglobulin
Febs J., 278, 2011
4FXL
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BU of 4fxl by Molmil
Crystal structure of the D76N Beta-2 Microglobulin mutant
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M.
登録日2012-07-03
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin.
N.Engl.J.Med., 366, 2012
4RMS
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BU of 4rms by Molmil
Crystal structure of the D53N Beta-2 Microglobulin mutant
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
著者de Rosa, M, Bolognesi, M, Ricagno, S.
登録日2014-10-22
公開日2015-11-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMT
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BU of 4rmt by Molmil
Crystal structure of the D98N Beta-2 Microglobulin mutant
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者de Rosa, M, Bolognesi, M, Ricagno, S.
登録日2014-10-22
公開日2015-11-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.242 Å)
主引用文献Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMQ
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BU of 4rmq by Molmil
Crystal structure of the D59N Beta-2 Microglobulin mutant
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
著者de Rosa, M, Bolognesi, M, Ricagno, S.
登録日2014-10-22
公開日2015-11-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.461 Å)
主引用文献Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMR
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BU of 4rmr by Molmil
Crystal structure of the D38N Beta-2 Microglobulin mutant
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
著者de Rosa, M, Bolognesi, M, Ricagno, S.
登録日2014-10-22
公開日2015-11-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.529 Å)
主引用文献Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
3EKC
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BU of 3ekc by Molmil
structure of W60V beta-2 microglobulin mutant
分子名称: Beta-2-microglobulin
著者Ricagno, S, Sangiovanni, E, Bellotti, V, Bolognesi, M.
登録日2008-09-19
公開日2009-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 380, 2009
2X89
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Structure of the Beta2_microglobulin involved in amyloidogenesis
分子名称: ANTIBODY, BETA-2-MICROGLOBULIN
著者Domanska, K, Srinivasan, V, Vanderhaegen, S, Pardon, E, Marquez, J.A, Bellotti, V, Wyns, L, Steyaert, J.
登録日2010-03-07
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Atomic Structure of a Nanobody-Trapped Domain-Swapped Dimer of an Amyloidogenic {Beta}2-Microglobulin Variant.
Proc.Natl.Acad.Sci.USA, 108, 2011
4MRB
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BU of 4mrb by Molmil
Wild Type Human Transthyretin pH 7.5
分子名称: CALCIUM ION, Transthyretin
著者Chen, W.J, Wood, S.P.
登録日2013-09-17
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MRC
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Human Transthyretin Ser52Pro Mutant
分子名称: CALCIUM ION, Transthyretin
著者Chen, W.J, Wood, S.P.
登録日2013-09-17
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proc.Natl.Acad.Sci.USA, 111, 2014

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