3DHM
Beta 2 microglobulin mutant D59P
Summary for 3DHM
Entry DOI | 10.2210/pdb3dhm/pdb |
Related | 2z9t 3DHJ |
Descriptor | Beta-2-microglobulin (2 entities in total) |
Functional Keywords | beta-2-microglobulin, proline, amyloidosis, dra, beta fibrils, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted, immune system |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P61769 |
Total number of polymer chains | 1 |
Total formula weight | 11861.38 |
Authors | Ricagno, S.,Colombo, M.,de Rosa, M.,Bolognesi, M.,Giorgetti, S.,Bellotti, V. (deposition date: 2008-06-18, release date: 2008-11-18, Last modification date: 2023-11-01) |
Primary citation | Ricagno, S.,Colombo, M.,de Rosa, M.,Sangiovanni, E.,Giorgetti, S.,Raimondi, S.,Bellotti, V.,Bolognesi, M. DE loop mutations affect beta2-microglobulin stability and amyloid aggregation Biochem.Biophys.Res.Commun., 377:146-150, 2008 Cited by PubMed: 18835253DOI: 10.1016/j.bbrc.2008.09.108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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