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3KUT
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BU of 3kut by Molmil
Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2
Descriptor: CHLORIDE ION, PAIP2 protein, Polyadenylate-binding protein 1
Authors:Kozlov, G, Gehring, K.
Deposit date:2009-11-27
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397, 2010
3KUJ
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BU of 3kuj by Molmil
Crystal structure of C-terminal domain of PABPC1 in complex with binding region of eRF3a
Descriptor: GSPT1 protein, Polyadenylate-binding protein 1, SULFATE ION
Authors:Kozlov, G, Gehring, K.
Deposit date:2009-11-27
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein.
Plos One, 5, 2010
3KUS
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BU of 3kus by Molmil
Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, PAIP2 protein, ...
Authors:Kozlov, G, Gehring, K.
Deposit date:2009-11-27
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397, 2010
3KUI
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BU of 3kui by Molmil
Crystal structure of C-terminal domain of PABPC1 in complex with binding region of eRF3a
Descriptor: GSPT1 protein, Polyadenylate-binding protein 1, SULFATE ION, ...
Authors:Kozlov, G, Gehring, K.
Deposit date:2009-11-27
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein.
Plos One, 5, 2010
3KUR
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BU of 3kur by Molmil
Crystal structure of the MLLE domain of poly(A)-binding protein
Descriptor: CHLORIDE ION, Polyadenylate-binding protein 1
Authors:Kozlov, G, Gehring, K.
Deposit date:2009-11-27
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397, 2010
6WUS
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BU of 6wus by Molmil
Crystal structure of PRL-1 phosphatase C104D mutant in complex with the Bateman domain of CNNM2 magnesium transporter
Descriptor: Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1
Authors:Kozlov, G, Gehring, K.
Deposit date:2020-05-05
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Crystal structure of PRL phosphatase C104D mutant in complex with the Bateman domain of CNNM magnesium transporter
J.Biol.Chem., 2020
8G91
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BU of 8g91 by Molmil
LaM domain of human LARP1 in complex with Rp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
8G90
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BU of 8g90 by Molmil
LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
8F6D
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BU of 8f6d by Molmil
Crystal structure of the CNNM2 CBS-pair domain in complex with ARL15
Descriptor: ADP-ribosylation factor-like protein 15, Metal transporter CNNM2
Authors:Kozlov, G, Mahbub, L, Gehring, K.
Deposit date:2022-11-16
Release date:2023-07-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15.
Elife, 12, 2023
8EY8
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BU of 8ey8 by Molmil
LaM domain of human LARP1 in complex with AAAAGA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*GP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2022-10-26
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural insights into poly(A) tail stabilization via 3'-end guanylation
To Be Published
8EY6
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BU of 8ey6 by Molmil
LaM domain of human LARP1 in complex with AAAAAG RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*G)-3'), SULFATE ION
Authors:Kozlov, G, Gehring, K.
Deposit date:2022-10-26
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural insights into poly(A) tail stabilization via 3'-end guanylation
To Be Published
8EY7
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BU of 8ey7 by Molmil
LaM domain of human LARP1 in complex with AAAGAA RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*GP*AP*A)-3')
Authors:Kozlov, G, Gehring, K.
Deposit date:2022-10-26
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into poly(A) tail stabilization via 3'-end guanylation
To Be Published
3DF0
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BU of 3df0 by Molmil
Calcium-dependent complex between m-calpain and calpastatin
Descriptor: CALCIUM ION, Calpain small subunit 1, Calpain-2 catalytic subunit, ...
Authors:Moldoveanu, T, Gehring, K, Green, D.R.
Deposit date:2008-06-11
Release date:2008-11-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
Nature, 456, 2008
6PIK
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BU of 6pik by Molmil
Tetrameric cryo-EM ArnA
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
6PIH
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BU of 6pih by Molmil
Hexameric ArnA cryo-EM structure
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
5K35
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BU of 5k35 by Molmil
Structure of the Legionella effector, AnkB, in complex with human Skp1
Descriptor: Ankyrin-repeat protein B, S-phase kinase-associated protein 1
Authors:Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2016-05-19
Release date:2017-01-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
5K34
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BU of 5k34 by Molmil
Structure of the ankyrin domain of AnkB from Legionella Pneumophila
Descriptor: Ankyrin-repeat protein B, GLYCEROL, SULFATE ION
Authors:Wong, K, Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2016-05-19
Release date:2017-01-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural Mimicry by a Bacterial F Box Effector Hijacks the Host Ubiquitin-Proteasome System.
Structure, 25, 2017
4EF0
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BU of 4ef0 by Molmil
Crystal Structure of the first catalytic domain of protein disulfide isomerase P5
Descriptor: Protein disulfide-isomerase A6
Authors:Vinaik, R, Kozlov, G, Gehring, K.
Deposit date:2012-03-28
Release date:2013-04-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of the first catalytic domain of protein disulfide isomerase P5
To be Published
6DJW
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BU of 6djw by Molmil
Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex
Descriptor: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
Authors:Sauve, V, Sung, G, Trempe, J.F, Gehring, K.
Deposit date:2018-05-26
Release date:2018-07-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.801 Å)
Cite:Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25, 2018
6DFD
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BU of 6dfd by Molmil
Crystal structure of CNNM3 cyclic nucleotide-binding homology domain
Descriptor: Metal transporter CNNM3
Authors:Kozlov, G, Gehring, K.
Deposit date:2018-05-14
Release date:2018-10-31
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+efflux activity.
J. Biol. Chem., 293, 2018
6DJX
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BU of 6djx by Molmil
Crystal Structure of pParkin-pUb-UbcH7 complex
Descriptor: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
Authors:Sauve, V, Sung, G, Trempe, J.F, Gehring, K.
Deposit date:2018-05-27
Release date:2018-07-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.801 Å)
Cite:Mechanism of parkin activation by phosphorylation.
Nat. Struct. Mol. Biol., 25, 2018
3BCY
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BU of 3bcy by Molmil
Crystal structure of YER067W
Descriptor: Protein YER067W
Authors:Kozlov, G, Gehring, K.
Deposit date:2007-11-13
Release date:2008-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional study of YER067W, a new protein involved in yeast metabolism control and drug resistance.
Plos One, 5, 2010
3BXY
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BU of 3bxy by Molmil
Crystal structure of tetrahydrodipicolinate N-succinyltransferase from E. coli
Descriptor: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Authors:Kozlov, G, Gehring, K, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2008-01-15
Release date:2008-01-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Escherichia coli tetrahydrodipicolinate N-succinyltransferase reveals the role of a conserved C-terminal helix in cooperative substrate binding.
Febs Lett., 582, 2008
3EC3
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BU of 3ec3 by Molmil
Crystal structure of the bb fragment of ERp72
Descriptor: Protein disulfide-isomerase A4
Authors:Kozlov, G, Gehring, K.
Deposit date:2008-08-28
Release date:2009-04-14
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of the Noncatalytic Domains and Global Fold of the Protein Disulfide Isomerase ERp72.
Structure, 17, 2009
5TDA
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BU of 5tda by Molmil
Crystal structure of the UBR-box domain from UBR2 in complex with RLWS N-degron
Descriptor: ARG-LEU-TRP-SER peptide, E3 ubiquitin-protein ligase UBR2, ZINC ION
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (0.79 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017

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