3H5W
 
 | | Crystal structure of the GluR2-ATD in space group P212121 without solvent | | Descriptor: | Glutamate receptor 2 | | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | Deposit date: | 2009-04-22 | | Release date: | 2009-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.686 Å) | | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
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3OEN
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3H5V
 | | Crystal structure of the GluR2-ATD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | Deposit date: | 2009-04-22 | | Release date: | 2009-06-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
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4PE5
 | | Crystal Structure of GluN1a/GluN2B NMDA Receptor Ion Channel | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, ... | | Authors: | Karakas, E, Furukawa, H. | | Deposit date: | 2014-04-22 | | Release date: | 2014-06-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.96 Å) | | Cite: | Crystal structure of a heterotetrameric NMDA receptor ion channel.
Science, 344, 2014
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7TE9
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7TES
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7TE4
 | | Crystal structure of Fab2 anti-GluN2B antibody | | Descriptor: | Fab anti-GluN2B antibody, heavy chain, Fab2 anti-GluN2B antibody, ... | | Authors: | Tajima, N, Furukawa, H. | | Deposit date: | 2022-01-04 | | Release date: | 2022-03-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.456 Å) | | Cite: | Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
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7TEB
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7TE6
 | | Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody | | Descriptor: | Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... | | Authors: | Regan, M, Tajima, N, Furukawa, H. | | Deposit date: | 2022-01-04 | | Release date: | 2022-03-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (4.55 Å) | | Cite: | Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
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7TER
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7TEE
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7TET
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7TEQ
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4JWY
 | | GluN2D ligand-binding core in complex with propyl-NHP5G | | Descriptor: | (2R)-amino(1-hydroxy-4-propyl-1H-pyrazol-5-yl)ethanoic acid, Glutamate receptor ionotropic, NMDA 2D | | Authors: | Hansen, K.B, Tajima, N, Risgaard, R, Perszyk, R.E, Jorgensen, L, Vance, K.M, Ogden, K.K, Clausen, R.P, Furukawa, H, Traynelis, S.F. | | Deposit date: | 2013-03-27 | | Release date: | 2013-05-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors.
Mol.Pharmacol., 84, 2013
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4NF6
 | | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and PPDA | | Descriptor: | (2S,3R)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ... | | Authors: | Jespersen, A, Tajima, N, Furukawa, H. | | Deposit date: | 2013-10-30 | | Release date: | 2014-03-12 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
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4NF8
 | | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and glutamate in PEG2000MME | | Descriptor: | GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ... | | Authors: | Jespersen, A, Tajima, N, Furukawa, H. | | Deposit date: | 2013-10-30 | | Release date: | 2014-03-12 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (1.856 Å) | | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
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4NF4
 | | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with DCKA and glutamate | | Descriptor: | 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ... | | Authors: | Annie, J, Tajima, N, Furukawa, H. | | Deposit date: | 2013-10-30 | | Release date: | 2014-03-12 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
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5B3J
 | | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil | | Descriptor: | Fab, heavy chain, light chain, ... | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-01 | | Release date: | 2016-05-11 | | Last modified: | 2022-03-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Nature, 534, 2016
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6E7W
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6E7S
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6E7U
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6E7X
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6E7V
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6E7T
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7SAB
 | | Phencyclidine-bound GluN1a-GluN2B NMDA receptors | | Descriptor: | 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Chou, T.-H, Furukawa, H. | | Deposit date: | 2021-09-22 | | Release date: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
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