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7K9I
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BU of 7k9i by Molmil
SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2B04 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B04 heavy chain, 2B04 light chain, ...
Authors:Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-29
Release date:2021-09-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9J
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BU of 7k9j by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2H04 heavy chain, ...
Authors:Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-29
Release date:2021-09-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9H
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BU of 7k9h by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B04 heavy chain, ...
Authors:Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-29
Release date:2021-09-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7KYL
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BU of 7kyl by Molmil
Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80
Descriptor: CHLORIDE ION, Envelope protein domain III, POWV-80 Fab heavy chain, ...
Authors:Errico, J.M, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-08
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.
J.Exp.Med., 218, 2021
2NZ1
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BU of 2nz1 by Molmil
Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The CC-Chemokine CCL2/MCP-1
Descriptor: Hypothetical protein GAMMAHV.M3, Small inducible cytokine A2
Authors:Alexander-Brett, J.M, Fremont, D.H.
Deposit date:2006-11-22
Release date:2007-12-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.
J.Exp.Med., 204, 2007
2NYZ
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BU of 2nyz by Molmil
Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The C- Chemokine XCL1
Descriptor: Hypothetical protein GAMMAHV.M3, Lymphotactin
Authors:Alexander-Brett, J.M, Fremont, D.H.
Deposit date:2006-11-21
Release date:2007-12-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.
J.Exp.Med., 204, 2007
2R29
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BU of 2r29 by Molmil
Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography
Descriptor: Envelope protein E, Heavy chain of Fab 1A1D-2, Light chain of Fab 1A1D-2
Authors:Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-08-24
Release date:2007-12-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
2QRI
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BU of 2qri by Molmil
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-28
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRT
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BU of 2qrt by Molmil
Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-29
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2QRS
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BU of 2qrs by Molmil
Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide.
Descriptor: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
Authors:Mitaksov, V.E, Fremont, D.H.
Deposit date:2007-07-29
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2R69
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BU of 2r69 by Molmil
Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution
Descriptor: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
Authors:Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-09-05
Release date:2007-12-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
1XAK
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BU of 1xak by Molmil
STRUCTURE OF THE SARS-CORONAVIRUS ORF7A ACCESSORY PROTEIN
Descriptor: SARS ORF7A ACCESSORY PROTEIN
Authors:Nelson, C.A, Lee, C.A, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-08-26
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein.
Structure, 13, 2005
1F3J
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BU of 1f3j by Molmil
HISTOCOMPATIBILITY ANTIGEN I-AG7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, LYSOZYME C, ...
Authors:Latek, R.R, Unanue, E.R, Fremont, D.H.
Deposit date:2000-06-04
Release date:2000-09-20
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice.
Immunity, 12, 2000
1FNE
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BU of 1fne by Molmil
HISTOCOMPATIBILITY ANTIGEN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (MHC CLASS II I-EK, ALPHA CHAIN), ...
Authors:Miley, M.J, Nelson, C.A, Fremont, D.H.
Deposit date:2000-08-21
Release date:2001-03-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional consequences of altering a peptide MHC anchor residue.
J.Immunol., 166, 2001
1FNG
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BU of 1fng by Molmil
HISTOCOMPATIBILITY ANTIGEN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (MHC CLASS II I-EK, ALPHA CHAIN), ...
Authors:Miley, M.J, Nelson, C.A, Fremont, D.H.
Deposit date:2000-08-21
Release date:2001-03-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional consequences of altering a peptide MHC anchor residue.
J.Immunol., 166, 2001
6MZK
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BU of 6mzk by Molmil
Crystal structure of hemagglutinin from influenza virus A/Pennsylvania/14/2010 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-11-05
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of hemagglutinin from influenza virus A/Pennsylvania/14/2010 (H3N2)
to be published
6MXU
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BU of 6mxu by Molmil
Crystal structure of hemagglutinin from influenza virus A/Texas/1/1977 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-10-31
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of hemagglutinin from influenza virus A/Texas/1/1977 (H3N2)
To be Published
6NK5
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BU of 6nk5 by Molmil
Electron Cryo-Microscopy Of Chikungunya VLP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Basore, K, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK7
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BU of 6nk7 by Molmil
Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.99 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK6
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BU of 6nk6 by Molmil
Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
Authors:Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-04
Release date:2019-05-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6P6P
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BU of 6p6p by Molmil
Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-06-04
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2)
To Be Published
6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
Descriptor: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
Authors:Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-07-01
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
1PQZ
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BU of 1pqz by Molmil
MURINE CYTOMEGALOVIRUS IMMUNOMODULATORY PROTEIN M144
Descriptor: Beta-2-microglobulin, MCMV M144
Authors:Miley, M.J, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:2003-06-19
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:MURINE CYTOMEGALOVIRUS IMMUNOMODULATORY PROTEIN M144
To be Published
1QTS
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BU of 1qts by Molmil
CRYSTAL STRUCTURE OF THE AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE
Descriptor: AP-2 CLATHRIN ADAPTOR ALPHA SUBUNIT (ALPHA-ADAPTIN C)
Authors:Traub, L.M, Downs, M.A, Westrich, J.L, Fremont, D.H.
Deposit date:1999-06-29
Release date:1999-07-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly.
Proc.Natl.Acad.Sci.USA, 96, 1999
1R0D
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BU of 1r0d by Molmil
HIP1R THATCH DOMAIN CORE
Descriptor: Huntingtin Interacting Protein 12
Authors:Brett, T.J, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
Deposit date:2003-09-19
Release date:2004-07-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural definition of the F-actin-binding THATCH domain from HIP1R
Nat.Struct.Mol.Biol., 13, 2006

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