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5A3I
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BU of 5a3i by Molmil
Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ...
著者Xiong, X, Corti, D, Liu, J, Pinna, D, Foglierini, M, Calder, L.J, Martin, S.R, Lin, Y.P, Walker, P.A, Collins, P.J, Monne, I, Suguitan Jr, A.L, Santos, C, Temperton, N.J, Subbarao, K, Lanzavecchia, A, Gamblin, S.J, Skehel, J.J.
登録日2015-06-01
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody.
Proc.Natl.Acad.Sci.USA, 112, 2015
5Y0A
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BU of 5y0a by Molmil
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
分子名称: protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
著者Wang, J.Q, Lok, S.M.
登録日2017-07-15
公開日2017-10-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
7SL5
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BU of 7sl5 by Molmil
Crystal Structure of VP12E7 Fab in complex with SARS-CoV-2 S fusion peptide
分子名称: Heavy chain VP12E7 Fab, Light chain VP12E7 Fab, PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-10-22
公開日2022-07-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7SKZ
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BU of 7skz by Molmil
Crystal Structure of VN01H1 Fab in complex with SARS-CoV-2 S fusion peptide
分子名称: Heavy chain of VN01H1 Fab, Light chain of VN01H1 Fab, PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN
著者Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-10-22
公開日2022-07-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
5OMZ
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BU of 5omz by Molmil
Solution structure of domain III (DIII)of Zika virus Envelope protein
分子名称: Envelope Protein
著者Zerbe, O, Bardelli, M.
登録日2017-08-02
公開日2017-10-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
6URM
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BU of 6urm by Molmil
Crystal structure of vaccine-elicited receptor-binding site targeting antibody LPAF-a.01 in complex with Hemagglutinin H1 A/California/04/2009
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Zhou, T, Cheung, S.F, Kwong, P.D.
登録日2019-10-23
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation.
Cell Rep, 32, 2020
7P40
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P5C3 is a potent fab neutralizer
分子名称: Spike glycoprotein, Variable Heavy Chain P5C3 (VH), Variable Light Chain P5C3 (VL)
著者perez, L.
登録日2021-07-09
公開日2021-10-13
最終更新日2023-04-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A highly potent antibody effective against SARS-CoV-2 variants of concern.
Cell Rep, 37, 2021
7PHG
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BU of 7phg by Molmil
MaP OF P5C3RBD Interface
分子名称: Heavy ChaIn variable, Light ChaIn, Surface glycoprotein
著者Perez, L.
登録日2021-08-17
公開日2021-10-13
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献A highly potent antibody effective against SARS-CoV-2 variants of concern.
Cell Rep, 37, 2021
6FG1
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BU of 6fg1 by Molmil
CRYSTAL STRUCTURE OF FAB OF NATALIZUMAB IN COMPLEX WITH FAB OF NAA32.
分子名称: GLYCEROL, HEAVY CHAIN OF FAB NAA32, HEAVY CHAIN OF FAB NATALIZUMAB, ...
著者Bertrand, T, Pouzieux, S.
登録日2018-01-09
公開日2019-07-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients.
Nat. Med., 25, 2019
6FG2
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CRYSTAL STRUCTURE OF FAB OF NATALIZUMAB IN COMPLEX WITH FAB OF NAA84.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEAVY CHAIN FAB NAA84, HEAVY CHAIN FAB NATALIZUMAB, ...
著者Bertrand, T, Pouzieux, S.
登録日2018-01-09
公開日2019-07-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.788 Å)
主引用文献A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients.
Nat. Med., 25, 2019
6BQB
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BU of 6bqb by Molmil
MGG4 Fab in complex with peptide
分子名称: GLYCEROL, MGG4 Fab heavy chain, MGG4 Fab light chain, ...
著者Oyen, D, Tan, J, Lanzavecchia, A, Wilson, I.A.
登録日2017-11-27
公開日2018-03-07
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.
Nat. Med., 24, 2018
7U0A
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BU of 7u0a by Molmil
Crystal Structure of C77G12 Fab in complex with SARS-CoV-2 S fusion peptide
分子名称: CHLORIDE ION, Heavy chain Fab C77G12, Light chain Fab C77G12, ...
著者Tortorici, M.A, Veesler, D.
登録日2022-02-17
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7U09
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BU of 7u09 by Molmil
Crystal Structure of C13B8 Fab in complex with SARS-CoV-2 S fusion peptide
分子名称: Heavy chain Fab C13B8, Light chain Fab C13B8, SARS-CoV-2 S fusion peptide
著者Tortorici, M.A, Veesler, D.
登録日2022-02-17
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7U0E
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BU of 7u0e by Molmil
Crystal Structure of C13C9 Fab in complex with SARS-CoV-2 S fusion peptide
分子名称: Heavy chain Fab C13C9, Light chain Fab C13C9, SARS-CoV-2 S fusion peptide
著者Tortorici, M.A, Veesler, D.
登録日2022-02-18
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7KHF
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BU of 7khf by Molmil
CryoEM structure of LILRB1 D3D4 domain-inserted antibody MDB1 Fab in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MDB1 Fab heavy chain, ...
著者Xu, K, Kwong, P.D.
登録日2020-10-21
公開日2021-03-31
最終更新日2021-05-05
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
7KFK
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BU of 7kfk by Molmil
Crystal structure of LILRB1 D3D4 domain in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Leukocyte immunoglobulin-like receptor subfamily B member 1, Rifin, ...
著者Xu, K, Kwong, P.D.
登録日2020-10-14
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
5JW5
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BU of 5jw5 by Molmil
Structure of MEDI8852 Fab Fragment
分子名称: MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION
著者Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2016-05-11
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW3
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BU of 5jw3 by Molmil
Structure of MEDI8852 Fab Fragment in Complex with H7 HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Collins, P.J, Neu, U, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2016-05-11
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW4
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BU of 5jw4 by Molmil
Structure of MEDI8852 Fab Fragment in Complex with H5 HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2016-05-11
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016

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