4PX7
| Crystal structure of lipid phosphatase E. coli PgpB | 分子名称: | GLYCEROL, LAURYL DIMETHYLAMINE-N-OXIDE, Phosphatidylglycerophosphatase | 著者 | Fan, J, Jiang, D, Zhao, Y, Zhang, X.C. | 登録日 | 2014-03-22 | 公開日 | 2014-05-28 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
6V8Q
| Structure of an inner membrane protein required for PhoPQ regulated increases in outer membrane cardiolipin | 分子名称: | (9Z,21R,24R,30R,33R,44Z)-24,27,30-trihydroxy-18,24,30,36-tetraoxo-19,23,25,29,31,35-hexaoxa-24lambda~5~,30lambda~5~-dip hosphatripentaconta-9,44-diene-21,33-diyl (9Z,9'Z)di-octadec-9-enoate, CALCIUM ION, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Fan, J, Miller, S. | 登録日 | 2019-12-11 | 公開日 | 2020-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.699585 Å) | 主引用文献 | Structure of an Inner Membrane Protein Required for PhoPQ-Regulated Increases in Outer Membrane Cardiolipin. Mbio, 11, 2020
|
|
2INF
| Crystal Structure of Uroporphyrinogen Decarboxylase from Bacillus subtilis | 分子名称: | Uroporphyrinogen decarboxylase | 著者 | Fan, J, Liu, Q, Hao, Q, Teng, M.K, Niu, L.W. | 登録日 | 2006-10-06 | 公開日 | 2006-10-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of uroporphyrinogen decarboxylase from Bacillus subtilis J.Bacteriol., 189, 2007
|
|
7DJC
| Crystal structure of the G26C/Q250A mutant of LeuT | 分子名称: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | 著者 | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | 登録日 | 2020-11-20 | 公開日 | 2021-04-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7DJ1
| Crystal structure of the G26C mutant of LeuT | 分子名称: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION | 著者 | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | 登録日 | 2020-11-19 | 公開日 | 2021-04-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.528 Å) | 主引用文献 | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7DII
| Crystal structure of LeuT in lipidic cubic phase at pH 7 | 分子名称: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION | 著者 | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | 登録日 | 2020-11-19 | 公開日 | 2021-04-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7DIX
| Crystal structure of LeuT in lipidic cubic phase at pH 5 | 分子名称: | Na(+):neurotransmitter symporter (Snf family), SELENOMETHIONINE, SODIUM ION | 著者 | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | 登録日 | 2020-11-19 | 公開日 | 2021-04-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7DJ2
| Crystal structure of the G26C/E290S mutant of LeuT | 分子名称: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | 著者 | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | 登録日 | 2020-11-19 | 公開日 | 2021-04-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7XJ0
| Structure of human TRPV3 in complex with Trpvicin | 分子名称: | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
|
|
7XJ3
| Structure of human TRPV3 | 分子名称: | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, fusion of transient receptor potential cation channel subfamily V member 3 and 3C-GFP | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
|
|
7XJ2
| Structure of human TRPV3_G573S in complex with Trpvicin in C4 symmetry | 分子名称: | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
|
|
7XJ1
| Structure of human TRPV3_G573S in complex with Trpvicin in C2 symmetry | 分子名称: | Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Fan, J, Yue, Z, Jiang, D, Lei, X. | 登録日 | 2022-04-14 | 公開日 | 2022-11-09 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural basis of TRPV3 inhibition by an antagonist. Nat.Chem.Biol., 19, 2023
|
|
8WR2
| Crystal Structure of Human Pyridoxal Kinase with bound Luteolin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, DIMETHYL SULFOXIDE, ... | 著者 | Fan, J, Zhu, Y. | 登録日 | 2023-10-12 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Discovery and characterization of natural product luteolin as an effective inhibitor of human pyridoxal kinase. Bioorg.Chem., 143, 2024
|
|
4CKH
| Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy | 分子名称: | ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 | 著者 | Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. | 登録日 | 2014-01-06 | 公開日 | 2014-10-15 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature. Dev.Cell, 31, 2014
|
|
4CKG
| Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy | 分子名称: | ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 | 著者 | Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. | 登録日 | 2014-01-06 | 公開日 | 2014-10-15 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature. Dev.Cell, 31, 2014
|
|
8SQF
| OXA-48 bound to inhibitor CDD-2725 | 分子名称: | (1M)-3'-(benzyloxy)-5-hydroxy[1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | 著者 | Park, S, Judge, A, Fan, J, Sankaran, B, Prasad, B.V.V, Palzkill, T. | 登録日 | 2023-05-04 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
|
|
8SQG
| OXA-48 bound to inhibitor CDD-2801 | 分子名称: | (1M)-3'-(benzyloxy)-5-[2-(methylamino)-2-oxoethoxy][1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | 著者 | Park, S, Judge, A, Fan, J, Sankaran, B, Palzkill, T. | 登録日 | 2023-05-04 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
|
|
6QJP
| Cryo-EM structure of heparin-induced 2N4R tau jagged filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
|
|
6QJH
| Cryo-EM structure of heparin-induced 2N4R tau snake filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
|
|
6QJM
| Cryo-EM structure of heparin-induced 2N4R tau twister filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
|
|
6QJQ
| Cryo-EM structure of heparin-induced 2N3R tau filaments | 分子名称: | Microtubule-associated protein tau | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | 登録日 | 2019-01-24 | 公開日 | 2019-02-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife, 8, 2019
|
|
3BS8
| Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Glutamate-1-semialdehyde 2,1-aminomutase | 著者 | Ge, H, Fan, J, Teng, M, Niu, L. | 登録日 | 2007-12-22 | 公開日 | 2008-12-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Glutamate1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate Biochem.Biophys.Res.Commun., 402, 2010
|
|
5H3D
| Helical structure of membrane tubules decorated by ACAP1 (BARPH doamin) protein by cryo-electron microscopy and MD simulation | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | 著者 | Chan, C, Pang, X.Y, Zhang, Y, Sun, F, Fan, J. | 登録日 | 2016-10-22 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages. Plos Comput.Biol., 15, 2019
|
|
5JQM
| Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 1.5 Angstroms Resolution | 分子名称: | Protein UPS1, mitochondrial,Mitochondrial distribution and morphology protein 35 | 著者 | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | 登録日 | 2016-05-05 | 公開日 | 2017-07-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1 Commun Biol, 2020
|
|
5JQL
| Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 2.9 Angstroms Resolution | 分子名称: | Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial | 著者 | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | 登録日 | 2016-05-05 | 公開日 | 2017-07-12 | 最終更新日 | 2020-09-02 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1 Commun Biol, 2020
|
|