8WR2

Crystal Structure of Human Pyridoxal Kinase with bound Luteolin

Summary for 8WR2

• Entry DOI: 10.2210/pdb8wr2/pdb
• Related PRD ID: PRD_900006
• Descriptor: Pyridoxal kinase, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, SODIUM ION, ... (7 entities in total)
• Functional Keywords: inhibitor, luteolin, pdxk, complex, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72611.15

Authors

Fan, J.,Zhu, Y. (deposition date: 2023-10-12, release date: 2024-03-20)

• Primary citation: Zhu, Y.,Bao, G.,Zhu, G.,Zhang, K.,Zhu, S.,Hu, J.,He, J.,Jiang, W.,Fan, J.,Dang, Y.; Discovery and characterization of natural product luteolin as an effective inhibitor of human pyridoxal kinase.; Bioorg.Chem., 143:107057-107057, 2024; PubMed: 38150934; DOI: 10.1016/j.bioorg.2023.107057

Experimental method

X-RAY DIFFRACTION (1.94 Å)