7DJ2

Crystal structure of the G26C/E290S mutant of LeuT

Summary for 7DJ2

• Entry DOI: 10.2210/pdb7dj2/pdb
• Related: 7DII 7DIX 7DJ1 7DJC
• Descriptor: Na(+):neurotransmitter symporter (Snf family), LEUCINE, SODIUM ION, ... (5 entities in total)
• Functional Keywords: neurotransmitter transporter, nss, slc6, transport protein
• Biological source: Aquifex aeolicus
• Total number of polymer chains: 2
• Total formula weight: 115806.55

Authors

Fan, J.,Xiao, Y.,Sun, Z.,Zhou, X. (deposition date: 2020-11-19, release date: 2021-04-07, Last modification date: 2023-11-29)

• Primary citation: Fan, J.,Xiao, Y.,Quick, M.,Yang, Y.,Sun, Z.,Javitch, J.A.,Zhou, X.; Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.; J.Biol.Chem., 296:100609-100609, 2021; PubMed: 33811858; DOI: 10.1016/j.jbc.2021.100609

Experimental method

X-RAY DIFFRACTION (2.4 Å)