7DJ2
Crystal structure of the G26C/E290S mutant of LeuT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Na(+):neurotransmitter symporter (Snf family) | polymer | 513 | 57456.7 | 2 | UniProt (O67854) Pfam (PF00209) | Aquifex aeolicus | LeuT |
| 2 | C, F (A, B) | LEUCINE | non-polymer | 131.2 | 2 | Chemie (LEU) | |||
| 3 | D, G (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, H (A, B) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 2 | Chemie (BOG) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 513 (UniProt: O67854)
| PDB | External Database | Details |
|---|---|---|
| Cys 26 | Gly 26 | engineered mutation |
| Ser 290 | Glu 290 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114913.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 893.1 | |
| All* | Total formula weight | 115806.5 |
