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5C3C
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BU of 5c3c by Molmil
Structural characterization of a newly identified component of alpha-carboxysomes: The AAA+ domain Protein cso-CbbQ
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CbbQ/NirQ/NorQ domain protein
Authors:Sutter, M, Kerfeld, C.A.
Deposit date:2015-06-17
Release date:2015-11-18
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Characterization of a Newly Identified Component of alpha-Carboxysomes: The AAA+ Domain Protein CsoCbbQ.
Sci Rep, 5, 2015
5D19
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BU of 5d19 by Molmil
Crystal structure of Mycobacterium tuberculosis Rv0302, form II
Descriptor: TetR family transcriptional regulator
Authors:Chou, T.-H, Delmar, J, Su, C.-C, Yu, E.
Deposit date:2015-08-04
Release date:2015-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.655 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302.
Protein Sci., 2015
5D1W
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BU of 5d1w by Molmil
Crystal structure of Mycobacterium tuberculosis Rv3249c transcriptional regulator.
Descriptor: PALMITIC ACID, Rv3249c transcriptional regulator
Authors:Chou, T.-H, Delmar, J, Su, C.-C, Yu, E.
Deposit date:2015-08-04
Release date:2015-09-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
4H6V
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BU of 4h6v by Molmil
Structure of Patellamide maturation protease PatA
Descriptor: Subtilisin-like protein
Authors:Nair, S.K, Agarwal, V.
Deposit date:2012-09-19
Release date:2012-10-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of cyanobactin maturation enzymes define a family of transamidating proteases.
Chem.Biol., 19, 2012
5D18
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BU of 5d18 by Molmil
Crystal structure of Mycobacterium tuberculosis Rv0302, form I
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL, SODIUM ION, ...
Authors:Chou, T.-H, Delmar, J, Su, C.-C, Yu, E.
Deposit date:2015-08-04
Release date:2015-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302.
Protein Sci., 2015
6JV4
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BU of 6jv4 by Molmil
Crystal structure of metallo-beta-lactamase VMB-1
Descriptor: CITRIC ACID, VMB-1, ZINC ION
Authors:Cheng, Q, Chen, S.
Deposit date:2019-04-15
Release date:2019-11-27
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Genetic and Biochemical Characterization of VMB-1, a Novel Metallo-beta-Lactamase Encoded by a Conjugative, Broad-Host Range IncC Plasmid from Vibrio spp.
Adv Biosyst, 4, 2020
5D9R
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BU of 5d9r by Molmil
Crystal structure of a conserved domain in the intermembrane space region of the plastid division protein ARC6
Descriptor: Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic
Authors:Radhakrishnan, A, Kumar, N, Su, C.-C, Chou, T.-H, Yu, E.
Deposit date:2015-08-18
Release date:2015-11-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Crystal structure of a conserved domain in the intermembrane space region of the plastid division protein ARC6.
Protein Sci., 25, 2016
4H6W
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BU of 4h6w by Molmil
Structure of Prenylagaramide maturation protease PagA
Descriptor: N-terminal cyanobactin protease
Authors:Nair, S.K, Agarwal, V.
Deposit date:2012-09-19
Release date:2012-10-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structures of cyanobactin maturation enzymes define a family of transamidating proteases.
Chem.Biol., 19, 2012
5D1R
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BU of 5d1r by Molmil
Crystal structure of Mycobacterium tuberculosis Rv1816 transcriptional regulator.
Descriptor: MAGNESIUM ION, NICKEL (II) ION, Rv1816 transcriptional regulator, ...
Authors:Chou, T.-H, Delmar, J, Su, C.-C, Yu, E.
Deposit date:2015-08-04
Release date:2015-09-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
4H6X
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BU of 4h6x by Molmil
Structure of Patellamide maturation protease PatG
Descriptor: Thiazoline oxidase/subtilisin-like protease
Authors:Nair, S.K, Agarwal, V.
Deposit date:2012-09-19
Release date:2012-10-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of cyanobactin maturation enzymes define a family of transamidating proteases.
Chem.Biol., 19, 2012
6MB0
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BU of 6mb0 by Molmil
Crystal structure of N-myristoyl transferase (NMT) G386E mutant from Plasmodium vivax in complex with inhibitor IMP-1002
Descriptor: 1,2-ETHANEDIOL, 1-(5-{4-fluoro-2-[2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethoxy]phenyl}-1-methyl-1H-indazol-3-yl)-N,N-dimethylmethanamine, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-08-29
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-Guided Identification of Resistance Breaking Antimalarial N‐Myristoyltransferase Inhibitors.
Cell Chem Biol, 26, 2019
6MB1
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BU of 6mb1 by Molmil
Crystal structure of N-myristoyl transferase (NMT) from Plasmodium vivax in complex with inhibitor IMP-1002
Descriptor: 1,2-ETHANEDIOL, 1-(5-{4-fluoro-2-[2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethoxy]phenyl}-1-methyl-1H-indazol-3-yl)-N,N-dimethylmethanamine, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-08-29
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-Guided Identification of Resistance Breaking Antimalarial N‐Myristoyltransferase Inhibitors.
Cell Chem Biol, 26, 2019
6MAZ
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BU of 6maz by Molmil
Crystal structure of N-myristoyl transferase (NMT) G386E mutant from Plasmodium vivax in complex with inhibitor IMP-0366
Descriptor: 1,2-ETHANEDIOL, 2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-08-29
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-Guided Identification of Resistance Breaking Antimalarial N‐Myristoyltransferase Inhibitors.
Cell Chem Biol, 26, 2019
6MAY
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BU of 6may by Molmil
Crystal structure of N-myristoyl transferase (NMT) G386E mutant from Plasmodium vivax
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Glycylpeptide N-tetradecanoyltransferase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-08-29
Release date:2019-06-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-Guided Identification of Resistance Breaking Antimalarial N‐Myristoyltransferase Inhibitors.
Cell Chem Biol, 26, 2019
6N40
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BU of 6n40 by Molmil
Crystal structure of MmpL3 from Mycobacterium smegmatis
Descriptor: Membrane protein, MmpL family protein
Authors:Su, C.-C.
Deposit date:2018-11-16
Release date:2019-02-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.307 Å)
Cite:Crystal structure of MmpL3 from Mycobacterium smegmatis
To be published
4K7K
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BU of 4k7k by Molmil
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
Descriptor: Cation efflux system protein CusC
Authors:Su, C.-C, Lei, H.-T.
Deposit date:2013-04-17
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal Structures of CusC Review Conformational Changes Accompanying Folding and Transmembrane Channel Formation.
J.Mol.Biol., 426, 2014
4K34
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BU of 4k34 by Molmil
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
Descriptor: Cation efflux system protein CusC
Authors:Su, C.-C.
Deposit date:2013-04-10
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Crystal Structures of CusC Review Conformational Changes Accompanying Folding and Transmembrane Channel Formation.
J.Mol.Biol., 426, 2014
3SH2
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BU of 3sh2 by Molmil
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)
Descriptor: 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Frey, K.M, Anderson, A.C.
Deposit date:2011-06-15
Release date:2012-03-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes.
Plos One, 7, 2012
3SGY
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BU of 3sgy by Molmil
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1006)
Descriptor: 6-ethyl-5-{(3S)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Frey, K.M, Anderson, A.C.
Deposit date:2011-06-15
Release date:2012-03-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes.
Plos One, 7, 2012
3U0T
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BU of 3u0t by Molmil
Fab-antibody complex
Descriptor: Amyloid beta A4 protein, ponezumab HC Fab, ponezumab LC Fab
Authors:LaPorte, S.L, Pons, J.P.
Deposit date:2011-09-29
Release date:2012-01-11
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of C-terminal beta-Amyloid Peptide Binding by the Antibody Ponezumab for the Treatment of Alzheimer's Disease
J.Mol.Biol., 421, 2012
4NN1
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BU of 4nn1 by Molmil
Crystal Structure of transcriptional regulator Rv1219c of Mycobacterium tuberculosis
Descriptor: Transcriptional regulator
Authors:Kumar, N, Radhakrishnan, A, Chou, T.-H, Yu, E.
Deposit date:2013-11-15
Release date:2014-02-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Crystal structure of the transcriptional regulator Rv1219c of Mycobacterium tuberculosis.
Protein Sci., 23, 2014
3VSO
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BU of 3vso by Molmil
Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt21
Descriptor: (2R)-2-benzyl-3-[4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)phenyl]propanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Oyama, T, Waku, T, Ohashi, M, Morikawa, K, Miyachi, H.
Deposit date:2012-04-30
Release date:2013-05-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and synthesis of a series of alpha-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility
Bioorg.Med.Chem., 21, 2013
3W56
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BU of 3w56 by Molmil
Structure of a C2 domain
Descriptor: C2 domain protein
Authors:Traore, D.A.K, Whisstock, J.C.
Deposit date:2013-01-24
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Defining the interaction of perforin with calcium and the phospholipid membrane.
Biochem.J., 456, 2013
3W57
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BU of 3w57 by Molmil
Structure of a C2 domain
Descriptor: C2 domain protein, CALCIUM ION
Authors:Traore, D.A.K, Whisstock, J.C.
Deposit date:2013-01-24
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Defining the interaction of perforin with calcium and the phospholipid membrane.
Biochem.J., 456, 2013
6QDC
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BU of 6qdc by Molmil
Leishmania major N-myristoyltransferase in complex with thienopyrimidine inhibitor IMP-0000101
Descriptor: 3-[[2-[(1-ethylpiperidin-4-yl)-methyl-amino]thieno[3,2-d]pyrimidin-4-yl]-methyl-amino]propanenitrile, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ...
Authors:Brannigan, J.A.
Deposit date:2019-01-01
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes.
J.Med.Chem., 63, 2020

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