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5CCC
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BU of 5ccc by Molmil
wild-type E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
Descriptor: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Oyen, D, Wright, P.E.
Deposit date:2015-07-01
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
1Z65
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BU of 1z65 by Molmil
Mouse Doppel 1-30 peptide
Descriptor: Prion-like protein doppel
Authors:Papadopoulos, E.
Deposit date:2005-03-21
Release date:2006-02-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Peptide Fragment 1-30, Derived from Unprocessed Mouse Doppel Protein, in DHPC Micelles
Biochemistry, 45, 2006
6DMX
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BU of 6dmx by Molmil
HBZ56 in complex with KIX and c-Myb
Descriptor: BZIP factor, CREB-binding protein, Transcriptional activator Myb
Authors:Yang, K, Wright, P.E, Stanfield, R.L.
Deposit date:2018-06-05
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DNQ
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BU of 6dnq by Molmil
HBZ77 in complex with KIX and c-Myb
Descriptor: 1,2-ETHANEDIOL, BZIP factor, CREB-binding protein, ...
Authors:Yang, K, Wright, P.E, Stanfield, R.L.
Deposit date:2018-06-07
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3QL3
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BU of 3ql3 by Molmil
Re-refined coordinates for PDB entry 1RX2
Descriptor: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2011-02-02
Release date:2011-04-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
3QL0
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BU of 3ql0 by Molmil
Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2011-02-02
Release date:2011-04-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Science, 332, 2011
2MKN
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BU of 2mkn by Molmil
Structural Characterization of Interactions between the Double-Stranded RNA-Binding Zinc Finger Protein JAZ and dsRNA
Descriptor: RNA (5'-R(*GP*CP*CP*GP*UP*GP*GP*UP*CP*UP*GP*GP*UP*GP*GP*CP*CP*GP*G)-3'), RNA (5'-R(P*CP*CP*GP*GP*CP*CP*AP*CP*CP*AP*GP*AP*CP*CP*AP*CP*GP*GP*C)-3'), ZINC ION, ...
Authors:Wright, P, Dyson, J, Burge, R, Martinez-Yamout, M.
Deposit date:2014-02-10
Release date:2014-03-19
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Structural Characterization of Interactions between the Double-Stranded RNA-Binding Zinc Finger Protein JAZ and Nucleic Acids.
Biochemistry, 53, 2014
2MKD
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BU of 2mkd by Molmil
Human JAZ ZF3 Residues 168-227
Descriptor: ZINC ION, Zinc finger protein 346
Authors:Wright, P, Dyson, J, Burge, R, Martinez-Yamout, M.
Deposit date:2014-02-05
Release date:2014-03-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Characterization of Interactions between the Double-Stranded RNA-Binding Zinc Finger Protein JAZ and Nucleic Acids.
Biochemistry, 53, 2014
2NC6
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BU of 2nc6 by Molmil
Solution Structure of N-L-idosylated Pin1 WW Domain
Descriptor: Pin1 WW Domain, beta-L-idopyranose
Authors:Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC5
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BU of 2nc5 by Molmil
Solution Structure of N-Xylosylated Pin1 WW Domain
Descriptor: Pin1 WW Domain, beta-D-xylopyranose
Authors:Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC3
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BU of 2nc3 by Molmil
Solution Structure of N-Allosylated Pin1 WW Domain
Descriptor: Pin1 WW Domain, beta-D-allopyranose
Authors:Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
2NC4
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BU of 2nc4 by Molmil
Solution Structure of N-Galactosylated Pin1 WW Domain
Descriptor: Pin1 WW Domain, beta-D-galactopyranose
Authors:Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W.
Deposit date:2016-03-20
Release date:2016-06-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
5W3Q
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BU of 5w3q by Molmil
L28F E.coli DHFR in complex with NADPH
Descriptor: CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Oyen, D, Wright, P.E, Wilson, I.A.
Deposit date:2017-06-08
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J. Am. Chem. Soc., 139, 2017
4M6L
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BU of 4m6l by Molmil
Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and 5,10-dideazatetrahydrofolic acid
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydrofolate reductase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2013-08-09
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
4M6J
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BU of 4m6j by Molmil
Crystal structure of human dihydrofolate reductase (DHFR) bound to NADPH
Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2013-08-09
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.201 Å)
Cite:Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
4M6K
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BU of 4m6k by Molmil
Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and folate
Descriptor: Dihydrofolate reductase, FOLIC ACID, GLYCEROL, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2013-08-09
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.396 Å)
Cite:Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
1RCY
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BU of 1rcy by Molmil
RUSTICYANIN (RC) FROM THIOBACILLUS FERROOXIDANS
Descriptor: COPPER (II) ION, RUSTICYANIN
Authors:Walter, R.L, Friedman, A.M, Ealick, S.E, Blake II, R.C, Proctor, P, Shoham, M.
Deposit date:1996-04-10
Release date:1997-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multiple wavelength anomalous diffraction (MAD) crystal structure of rusticyanin: a highly oxidizing cupredoxin with extreme acid stability.
J.Mol.Biol., 263, 1996
2JOX
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BU of 2jox by Molmil
Embryonic Neural Inducing Factor Churchill is not a DNA-Binding Zinc Finger Protein: Solution Structure Reveals a Solvent-Exposed beta-Sheet and Zinc Binuclear Cluster
Descriptor: Churchill protein, ZINC ION
Authors:Lee, B.M, Buck-Koehntop, B.A, Martinez-Yamout, M.A, Gottesfeld, J.M, Dyson, H, Wright, P.E.
Deposit date:2007-04-07
Release date:2007-08-21
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Embryonic Neural Inducing Factor Churchill Is not a DNA-binding Zinc Finger Protein: Solution Structure Reveals a Solvent-exposed beta-Sheet and Zinc Binuclear Cluster
J.Mol.Biol., 371, 2007
2KJE
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BU of 2kje by Molmil
NMR structure of CBP TAZ2 and adenoviral E1A complex
Descriptor: CREB-binding protein, Early E1A 32 kDa protein, ZINC ION
Authors:Ferreon, J.C, Martinez-Yamout, M, Dyson, H, Wright, P.E.
Deposit date:2009-05-27
Release date:2009-09-15
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.
Proc.Natl.Acad.Sci.USA, 106, 2009
2LT7
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BU of 2lt7 by Molmil
Solution NMR structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
Descriptor: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ...
Authors:Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H, Wilson, I.A, Wright, P.E.
Deposit date:2012-05-15
Release date:2012-09-05
Last modified:2012-10-03
Method:SOLUTION NMR
Cite:Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
1A3Z
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BU of 1a3z by Molmil
REDUCED RUSTICYANIN AT 1.9 ANGSTROMS
Descriptor: COPPER (I) ION, RUSTICYANIN
Authors:Zhao, D, Shoham, M.
Deposit date:1998-01-27
Release date:1998-07-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rusticyanin: Extremes in acid stability and redox potential explained by the crystal structure.
Biophys.J., 74, 1998
1A8Z
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BU of 1a8z by Molmil
STRUCTURE DETERMINATION OF A 16.8KDA COPPER PROTEIN RUSTICYANIN AT 2.1A RESOLUTION USING ANOMALOUS SCATTERING DATA WITH DIRECT METHODS
Descriptor: COPPER (I) ION, RUSTICYANIN
Authors:Harvey, I, Hao, Q, Duke, E.M.H, Ingledew, W.J, Hasnain, S.S.
Deposit date:1998-03-30
Release date:1998-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure determination of a 16.8 kDa copper protein at 2.1 A resolution using anomalous scattering data with direct methods.
Acta Crystallogr.,Sect.D, 54, 1998
2KBU
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BU of 2kbu by Molmil
NMR solution structure of Pin1 WW domain mutant with beta turn mimic at position 12
Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Authors:Fuller, A.A, Bhabha, G, Case, D.A.
Deposit date:2008-12-08
Release date:2009-07-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Evaluating beta-turn mimics as beta-sheet folding nucleators.
Proc.Natl.Acad.Sci.USA, 106, 2009
7D9L
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BU of 7d9l by Molmil
Crystal structure of E. coli Grx2: Enzyme inhibited state in complex with Zinc and glutathione sulfinic acid
Descriptor: CHLORIDE ION, Glutaredoxin, L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE, ...
Authors:Sreekumar, S.N, Arockiasamy, A.
Deposit date:2020-10-13
Release date:2021-10-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal structure of E. coli Grx2: Enzyme inhibited state in complex with Zinc and glutathione sulfinic acid
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