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3DPL
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BU of 3dpl by Molmil
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation.
分子名称: Cullin-5, RING-box protein 1, ZINC ION
著者Duda, D.M, Schulman, B.A.
登録日2008-07-08
公開日2008-09-30
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
3DQV
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BU of 3dqv by Molmil
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation
分子名称: Cullin-5, NEDD8, Rbx1, ...
著者Duda, D.M, Borg, L.A, Scott, D.C, Hunt, H.W, Hammel, M, Schulman, B.A.
登録日2008-07-09
公開日2008-09-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134, 2008
1ZFN
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BU of 1zfn by Molmil
Structural Analysis of Escherichia coli ThiF
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Adenylyltransferase thiF, ZINC ION
著者Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A.
登録日2005-04-20
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
1Z97
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BU of 1z97 by Molmil
Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer.
分子名称: Carbonic anhydrase III, ZINC ION
著者Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R.
登録日2005-03-31
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1ZKM
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BU of 1zkm by Molmil
Structural Analysis of Escherichia Coli ThiF
分子名称: Adenylyltransferase thiF, ZINC ION
著者Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A.
登録日2005-05-03
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
1Z93
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BU of 1z93 by Molmil
Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer.
分子名称: Carbonic anhydrase III, ZINC ION
著者Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R.
登録日2005-03-31
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
2EKE
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BU of 2eke by Molmil
Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a noncovalent Ubiquitin-like protein-E2 complex as a platform for selective interactions within a SUMO pathway
分子名称: SUMO-conjugating enzyme UBC9, Ubiquitin-like protein SMT3
著者Duda, D.M, Schulman, B.A.
登録日2007-03-23
公開日2007-05-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway
J.Mol.Biol., 369, 2007
4F52
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BU of 4f52 by Molmil
Structure of a Glomulin-RBX1-CUL1 complex
分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ...
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2012-05-11
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface.
Mol.Cell, 47, 2012
4KBL
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BU of 4kbl by Molmil
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
分子名称: E3 ubiquitin-protein ligase ARIH1, ZINC ION
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2013-04-23
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.
Structure, 21, 2013
4KC9
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BU of 4kc9 by Molmil
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
分子名称: E3 ubiquitin-protein ligase ARIH1, ZINC ION
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2013-04-24
公開日2013-05-29
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (3.603 Å)
主引用文献Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.
Structure, 21, 2013
8CAF
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BU of 8caf by Molmil
N8C_Fab3b in complex with NEDD8-CUL1(WHB)
分子名称: Cullin-1, Fab Heavy Chain, Fab Light Chain, ...
著者Duda, D.M, Yanishevski, D, Henneberg, L.T, Schulman, B.A.
登録日2023-01-24
公開日2023-09-13
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Activity-based profiling of cullin-RING E3 networks by conformation-specific probes.
Nat.Chem.Biol., 19, 2023
3RTR
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BU of 3rtr by Molmil
A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases
分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, ZINC ION
著者Calabrese, M.F, Scott, D.C, Duda, D.M, Grace, C.R, Kurinov, I, Kriwacki, R.W, Schulman, B.A.
登録日2011-05-03
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases.
Nat.Struct.Mol.Biol., 18, 2011
3FN1
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BU of 3fn1 by Molmil
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.
分子名称: NEDD8-activating enzyme E1 catalytic subunit, NEDD8-conjugating enzyme UBE2F
著者Huang, D.T, Ayrault, O, Hunt, H.W, Taherbhoy, A.M, Duda, D.M, Scott, D.C, Borg, L.A, Neale, G, Murray, P.J, Roussel, M.F, Schulman, B.A.
登録日2008-12-22
公開日2009-03-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Mol.Cell, 33, 2009
3O6B
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BU of 3o6b by Molmil
A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) low resolution
分子名称: Cell division control protein 53, Defective in cullin neddylation protein 1
著者Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
登録日2010-07-28
公開日2010-09-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O2U
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BU of 3o2u by Molmil
S. cerevisiae Ubc12
分子名称: GLYCEROL, NEDD8-conjugating enzyme UBC12
著者Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
登録日2010-07-22
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
3O2P
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BU of 3o2p by Molmil
A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB)
分子名称: Cell division control protein 53, Defective in cullin neddylation protein 1, GLYCEROL
著者Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A.
登録日2010-07-22
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.233 Å)
主引用文献A dual E3 mechanism for Rub1 ligation to Cdc53.
Mol.Cell, 39, 2010
2GJD
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BU of 2gjd by Molmil
Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress
分子名称: Ubiquitin-conjugating enzyme E2-18 kDa
著者van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A.
登録日2006-03-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress.
Mol.Cell.Biol., 26, 2006
4GSJ
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BU of 4gsj by Molmil
Crystal structure of Atg7 NTD K14A F16A D18A mutant
分子名称: CITRIC ACID, ISOPROPYL ALCOHOL, Ubiquitin-like modifier-activating enzyme ATG7
著者Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A.
登録日2012-08-27
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
4GSL
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BU of 4gsl by Molmil
Crystal structure of an Atg7-Atg3 crosslinked complex
分子名称: Autophagy-related protein 3, Ubiquitin-like modifier-activating enzyme ATG7, ZINC ION
著者Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A.
登録日2012-08-27
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
4GSK
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BU of 4gsk by Molmil
Crystal structure of an Atg7-Atg10 crosslinked complex
分子名称: Ubiquitin-like modifier-activating enzyme ATG7, Ubiquitin-like-conjugating enzyme ATG10, ZINC ION
著者Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A.
登録日2012-08-27
公開日2012-11-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures.
Nat.Struct.Mol.Biol., 19, 2012
1MOO
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BU of 1moo by Molmil
Site Specific Mutant (H64A) of Human Carbonic Anhydrase II at high resolution
分子名称: 4-METHYLIMIDAZOLE, Carbonic Anhydrase II, MERCURY (II) ION, ...
著者Duda, D.M, Govindasamy, L, Agbandje-McKenna, M, Tu, C.K, Silverman, D.N, McKenna, R.
登録日2002-09-09
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.
Acta Crystallogr.,Sect.D, 59, 2003
5UDH
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BU of 5udh by Molmil
HHARI/ARIH1-UBCH7~Ubiquitin
分子名称: E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ...
著者Miller, D.J, Schulman, B.A.
登録日2016-12-27
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017
1LZV
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BU of 1lzv by Molmil
Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II
分子名称: Carbonic Anhydrase II, ZINC ION
著者Tu, C.K, Qian, M, An, H, Wadhwa, N.R, Duda, D.M, Yoshioka, C, Pathak, Y, McKenna, R, Laipis, P.J, Silverman, D.N.
登録日2002-06-11
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.
J.Biol.Chem., 277, 2002
3HQM
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BU of 3hqm by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-CiSBC2
分子名称: Protein cubitus interruptus, SULFATE ION, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-07
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQL
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BU of 3hql by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases:SPOPMATHx-PucSBC1_pep2
分子名称: Puckered, SULFATE ION, Speckle-type POZ protein
著者Zhuang, M, Schulman, B.A.
登録日2009-06-07
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009

 

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