6D0T
 
 | | De novo design of a fluorescence-activating beta barrel - BB1 | | 分子名称: | BB1 | | 著者 | Dou, J, Vorobieva, A.A, Sheffler, W, Doyle, L.A, Park, H, Bick, M.J, Mao, B, Foight, G.W, Lee, M, Carter, L, Sankaran, B, Ovchinnikov, S, Marcos, E, Huang, P, Vaughan, J.C, Stoddard, B.L, Baker, D. | | 登録日 | 2018-04-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
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5IER
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5IF6
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6CZI
 | | Structure of a redesigned beta barrel, mFAP1, bound to DFHBI | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP1 | | 著者 | Doyle, L.A, Stoddard, B.L. | | 登録日 | 2018-04-09 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
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6CZG
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6CZJ
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6CZH
 | | Structure of a redesigned beta barrel, mFAP0, bound to DFHBI | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP0 | | 著者 | Doyle, L.A, Stoddard, B.L. | | 登録日 | 2018-04-09 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
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6O35
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6OHH
 | | Structure of EF1p2_mFAP2b bound to DFHBI | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, CALCIUM ION, EF1p2_mFAP2b | | 著者 | Doyle, L.A, Stoddard, B.L. | | 登録日 | 2019-04-05 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
Nat Commun, 12, 2021
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4J8T
 | | Engineered Digoxigenin binder DIG10.2 | | 分子名称: | DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.2 | | 著者 | Stoddard, B.L, Doyle, L.A. | | 登録日 | 2013-02-14 | | 公開日 | 2013-06-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Computational design of ligand-binding proteins with high affinity and selectivity.
Nature, 501, 2013
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5TRV
 | | Crystal structure of a de novo designed protein with curved beta-sheet | | 分子名称: | DI(HYDROXYETHYL)ETHER, denovo NTF2 | | 著者 | Basanta, B, Oberdorfer, G, Marcos, E, Chidyausiku, T.M, Sankaran, B, Baker, D. | | 登録日 | 2016-10-27 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
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5TPJ
 | | Crystal structure of a de novo designed protein with curved beta-sheet | | 分子名称: | denovo NTF2 | | 著者 | Basanta, B, Oberdorfer, G, Marcos, E, Chidyausiku, T.M, Sankaran, B, Baker, D. | | 登録日 | 2016-10-20 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.101 Å) | | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
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5TPH
 | | Crystal structure of a de novo designed protein homodimer with curved beta-sheet | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, de novo NTF2 homodimer | | 著者 | Basanta, B, Marcos, E, Oberdorfer, G, Chidyausiku, T.M, Sankaran, B, Baker, D. | | 登録日 | 2016-10-20 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
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5TS4
 | | Crystal structure of a de novo designed protein with curved beta-sheet | | 分子名称: | DI(HYDROXYETHYL)ETHER, denovo NTF2 | | 著者 | Basanta, B, Oberdorfer, G, Chidyausiku, T.M, Marcos, E, Pereira, J.H, Sankaran, B, Zwart, P.H, Baker, D. | | 登録日 | 2016-10-27 | | 公開日 | 2017-01-25 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
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5U35
 | | Crystal structure of a de novo designed protein with curved beta-sheet | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-METHOXYETHANOL, CHLORIDE ION, ... | | 著者 | Oberdorfer, G, Marcos, E, Basanta, B, Chidyausiku, T.M, Sankaran, B, Zwart, P.H, Baker, D. | | 登録日 | 2016-12-01 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
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7SKN
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7SKO
 | | De novo synthetic protein DIG8-CC (orthogonal space group) | | 分子名称: | De novo synthetic protein DIG8-CC, MAGNESIUM ION | | 著者 | Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. | | 登録日 | 2021-10-21 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | De novo design of immunoglobulin-like domains
Nat Commun, 13, 2022
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7SKP
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6TMS
 | | Crystal structure of a de novo designed hexameric helical-bundle protein | | 分子名称: | SULFATE ION, a novel designed pore protein, affinity purification tag | | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | | 登録日 | 2019-12-05 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-09-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Computational design of transmembrane pores.
Nature, 585, 2020
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6TJ1
 | | Crystal structure of a de novo designed hexameric helical-bundle protein | | 分子名称: | De novo designed WSHC6, purification tag | | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | | 登録日 | 2019-11-23 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-09-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Computational design of transmembrane pores.
Nature, 585, 2020
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4J9A
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5BVB
 | | Engineered Digoxigenin binder DIG5.1a | | 分子名称: | DIG5.1a, DIGOXIGENIN | | 著者 | Doyle, L.A, Stoddard, B.L. | | 登録日 | 2015-06-04 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | CSAR Benchmark Exercise 2013: Evaluation of Results from a Combined Computational Protein Design, Docking, and Scoring/Ranking Challenge.
J.Chem.Inf.Model., 56, 2016
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5KPH
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5L33
 | | Crystal structure of a de novo designed protein with curved beta-sheet | | 分子名称: | denovo NTF2 | | 著者 | Oberdorfer, G, Marcos, E, Basanta, B, Chidyausiku, T.M, Sankaran, B, Baker, D. | | 登録日 | 2016-08-03 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
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5KPE
 | | Solution NMR Structure of Denovo Beta Sheet Design Protein, Northeast Structural Genomics Consortium (NESG) Target OR664 | | 分子名称: | De novo Beta Sheet Design Protein OR664 | | 著者 | Tang, Y, Liu, G, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2016-07-03 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
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