6OHH

Structure of EF1p2_mFAP2b bound to DFHBI

Summary for 6OHH

• Entry DOI: 10.2210/pdb6ohh/pdb
• Descriptor: EF1p2_mFAP2b, CALCIUM ION, (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, ... (4 entities in total)
• Functional Keywords: rossetta, ligand binder, computational, beta barrel, ef-motif, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 28457.18

Authors

Doyle, L.A.,Stoddard, B.L. (deposition date: 2019-04-05, release date: 2020-04-08, Last modification date: 2024-03-13)

• Primary citation: Klima, J.C.,Doyle, L.A.,Lee, J.D.,Rappleye, M.,Gagnon, L.A.,Lee, M.Y.,Barros, E.P.,Vorobieva, A.A.,Dou, J.,Bremner, S.,Jacob, S.,Quon, J.S.,Chow, C.M.,Carter, L.,Mack, D.L.,Amaro, R.E.,Vaughan, J.C.,Berndt, A.,Stoddard, B.L.,Baker, D.; Incorporation of sensing modalities into de novo designed fluorescence-activating proteins; Nat Commun, 12:856-, 2021; DOI: 10.1038/s41467-020-18911-w

Experimental method

X-RAY DIFFRACTION (2.1 Å)