8WA8
| Human transketolase in complex with phosphite | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, PHOSPHITE ION, ... | Authors: | Liu, Z, Tittmann, K, Dai, S. | Deposit date: | 2023-09-07 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis Acs Catalysis, 14, 2024
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8WA9
| Human transketolase soaked with donor ketose D-fructose | Descriptor: | 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ... | Authors: | Liu, Z, Tittmann, K, Dai, S. | Deposit date: | 2023-09-07 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis Acs Catalysis, 14, 2024
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8WAA
| Human transketolase soaked with donor ketose D-xylulose | Descriptor: | 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ... | Authors: | Liu, Z, Dai, S, Tittmann, K. | Deposit date: | 2023-09-07 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis Acs Catalysis, 14, 2024
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4H1L
| TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy | Descriptor: | Ani2.3 TCR A chain, Ani2.3 TCR B chain, HLA class II histocompatibility antigen, ... | Authors: | Kappler, J.W, Yin, L, Dai, S, Marrack, P. | Deposit date: | 2012-09-10 | Release date: | 2012-11-14 | Last modified: | 2013-09-04 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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4H26
| TCR interaction with peptide mimics of nickel offers structure insight to nickel contact allergy | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. | Deposit date: | 2012-09-12 | Release date: | 2013-10-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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1PQ1
| Crystal structure of Bcl-xl/Bim | Descriptor: | Apoptosis regulator Bcl-X, BCL2-like protein 11 | Authors: | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | Deposit date: | 2003-06-17 | Release date: | 2003-09-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
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1PQ0
| Crystal structure of mouse Bcl-xl | Descriptor: | Apoptosis regulator Bcl-X | Authors: | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | Deposit date: | 2003-06-17 | Release date: | 2003-09-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
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5UJT
| Crystal structure of human HLA-DQ8 in complex with insulin mimotope binding in register 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-beta-1, ... | Authors: | Wang, Y, Dai, S. | Deposit date: | 2017-01-18 | Release date: | 2017-12-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5W1L
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5W1J
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6DFX
| human diabetogenic TCR T1D3 in complex with DQ8-p8E9E peptide | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, Y, Dai, S. | Deposit date: | 2018-05-15 | Release date: | 2019-04-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
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6DFQ
| mouse diabetogenic TCR I.29 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, TCR alpha chain, ... | Authors: | Wang, Y, Dai, S. | Deposit date: | 2018-05-15 | Release date: | 2019-04-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
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6DFV
| Mouse diabetogenic TCR 8F10 | Descriptor: | 1,2-ETHANEDIOL, TCR alpha chain, TCR beta chain | Authors: | Wang, Y, Dai, S. | Deposit date: | 2018-05-15 | Release date: | 2019-04-17 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
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6DFW
| TCR 8F10 in complex with IAg7-p8G9E | Descriptor: | 8F10 alpha chain, 8F10 beta chain, H-2 class II histocompatibility antigen, ... | Authors: | Wang, Y, Dai, S. | Deposit date: | 2018-05-15 | Release date: | 2019-04-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
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6DFS
| mouse TCR I.29 in complex with IAg7-p8E9E6ss | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A-D alpha chain, ... | Authors: | Wang, Y, Dai, S. | Deposit date: | 2018-05-15 | Release date: | 2019-04-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4, 2019
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4P5K
| Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity | Descriptor: | HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ... | Authors: | Clayton, G.M, Wang, Y, Crawford, F, Novikov, A, Wimberly, B.T, Kieft, J.S, Falta, M.T, Bowerman, N.A, Marrack, P, Fontenot, A.P, Dai, S, Kappler, J.W. | Deposit date: | 2014-03-17 | Release date: | 2015-01-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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4P5M
| Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wang, Y, Dai, S, Kappler, J. | Deposit date: | 2014-03-18 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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5DMK
| Crystal Structure of IAg7 in complex with RLGL-WE14 | Descriptor: | CITRATE ANION, H-2 class II histocompatibility antigen, A-D alpha chain, ... | Authors: | Wang, Y, Jin, N, Dai, S, Kappler, J.W. | Deposit date: | 2015-09-08 | Release date: | 2015-10-28 | Last modified: | 2016-04-06 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc.Natl.Acad.Sci.USA, 112, 2015
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2G5B
| Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide. | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6A7 Fab Heavy Chain, 6A7 Fab Light Chain, ... | Authors: | Peyerl, F.W, Dai, S, Murphy, G.A, Marrack, P, Kappler, J.W. | Deposit date: | 2006-02-22 | Release date: | 2006-07-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex. Cell Death Differ., 14, 2007
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2GP5
| Crystal structure of catalytic core domain of jmjd2A complexed with alpha-Ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, Jumonji domain-containing protein 2A, ... | Authors: | Chen, Z, Zang, J, Whetstine, J, Hong, X, Davrazou, F, Kutateladze, T.G, Simpson, M, Dai, S, Hagman, J, Shi, Y, Zhang, G. | Deposit date: | 2006-04-16 | Release date: | 2006-05-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural insights into histone demethylation by JMJD2 family members Cell(Cambridge,Mass.), 125, 2006
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2GP3
| Crystal structure of the catalytic core domain of jmjd2a | Descriptor: | FE (II) ION, Jumonji domain-containing protein 2A, ZINC ION | Authors: | Chen, Z, Zang, J, Whetstine, J, Hong, X, Davrazou, F, Kutateladze, T.G, Simpson, M, Dai, S, Hagman, J, Shi, Y, Zhang, G. | Deposit date: | 2006-04-16 | Release date: | 2006-05-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into histone demethylation by JMJD2 family members Cell(Cambridge,Mass.), 125, 2006
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8JWN
| Crystal structure of AKRtyl-NADPH complex | Descriptor: | Aldo/keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Lin, S, Dai, S, Xiao, Z. | Deposit date: | 2023-06-29 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D. Nat Commun, 15, 2024
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4H25
| TCR interaction with peptide mimics of nickel offers structure insights to nickel contact allergy | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. | Deposit date: | 2012-09-12 | Release date: | 2013-10-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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1KT2
| CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, ... | Authors: | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | Deposit date: | 2002-01-15 | Release date: | 2002-05-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
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1KTD
| CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ... | Authors: | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | Deposit date: | 2002-01-15 | Release date: | 2002-05-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
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