Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1H4V
DownloadVisualize
BU of 1h4v by Molmil
HISTIDYL-TRNA SYNTHETASE from Thermus Thermophilus (ligand free)
Descriptor: HISTIDYL-TRNA SYNTHETASE, SULFATE ION
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2001-05-14
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
2BYT
DownloadVisualize
BU of 2byt by Molmil
Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation
Descriptor: LEUCINE, LEUCYL-TRNA SYNTHETASE, MERCURY (II) ION, ...
Authors:Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S.
Deposit date:2005-08-04
Release date:2005-09-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer-Editing Conformation.
Nat.Struct.Mol.Biol., 12, 2005
2BTE
DownloadVisualize
BU of 2bte by Molmil
Thermus thermophilus Leucyl-tRNA synthetase complexed with a tRNAleu transcript in the post-editing conformation and a post- transfer editing substrate analogue
Descriptor: 2'-AMINO-2'-DEOXYADENOSINE, AMINOACYL-TRNA SYNTHETASE, LEUCINE, ...
Authors:Cusack, S, Tukalo, M, Yaremchuk, A, Fukunaga, R, Yokoyama, S.
Deposit date:2005-05-31
Release date:2005-09-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Crystal Structure of Leucyl-tRNA Synthetase Complexed with tRNA(Leu) in the Post-Transfer- Editing Conformation.
Nat.Struct.Mol.Biol., 12, 2005
5OOB
DownloadVisualize
BU of 5oob by Molmil
COMPLEX OF HUMAN NUCLEAR CAP-BINDING COMPLEX WITH M7GTP AND NELF-E C-TERMINAL PEPTIDE
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Negative elongation factor E, Nuclear cap-binding protein subunit 1, ...
Authors:Cusack, S, Schulze, W.M.
Deposit date:2017-08-07
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2.
Nat Commun, 8, 2017
5OO6
DownloadVisualize
BU of 5oo6 by Molmil
Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Cusack, S, Schulze, W.M.
Deposit date:2017-08-06
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2.
Nat Commun, 8, 2017
6EUX
DownloadVisualize
BU of 6eux by Molmil
Structure of the midlink and cap-binding domains of influenza B polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor
Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2
Authors:Cusack, S, Gaudon, S.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EUY
DownloadVisualize
BU of 6euy by Molmil
Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor
Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2, SULFATE ION
Authors:Cusack, S, Gaudon, S.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EUW
DownloadVisualize
BU of 6euw by Molmil
Crystal structure of the cap-binding domain of the PB2 subunit of influenza A/H5N1 polymerase bound to an azaindazole inhibitor
Descriptor: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, GLYCEROL, Polymerase basic protein 2
Authors:Cusack, S, Gaudon, S.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6EUV
DownloadVisualize
BU of 6euv by Molmil
Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787)
Descriptor: (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, NICKEL (II) ION, Polymerase basic protein 2
Authors:Cusack, S, Lethier, M.
Deposit date:2017-10-31
Release date:2017-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
5JCH
DownloadVisualize
BU of 5jch by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.95 A resolution (untwinned).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JBG
DownloadVisualize
BU of 5jbg by Molmil
Crystal structure of chicken LGP2 with 5'ppp 26-mer hairpin RNA with 3' GG overhang and ADP-AlF4-Mg2+ at 2.0 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LGP2, MAGNESIUM ION, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JBJ
DownloadVisualize
BU of 5jbj by Molmil
Crystal structure of chicken LGP2 with 5'p 12-mer dsRNA at 3.6 A resolution
Descriptor: LGP2, RNA (5'-R(P*GP*GP*UP*AP*GP*CP*GP*CP*UP*AP*CP*C)-3'), ZINC ION
Authors:Cusack, S, Uchikawa, E, Lethier, M.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC3
DownloadVisualize
BU of 5jc3 by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (monoclinic form, twinned).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JCF
DownloadVisualize
BU of 5jcf by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (orthorhombic form).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC7
DownloadVisualize
BU of 5jc7 by Molmil
Crystal structure of chicken MDA5 with 5'p 24-mer dsRNA and ADP-Mg2+ at 2.75 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JAJ
DownloadVisualize
BU of 5jaj by Molmil
Structure of chicken LGP2 witha 5'p 10-mer dsRNA and ADP-AlF4-Mg.
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, LGP2, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-12
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JB2
DownloadVisualize
BU of 5jb2 by Molmil
Crystal structure of chicken LGP2 with 5'ppp 10-mer dsRNA and ADP-AlF4-Mg2+ at 2.2 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LGP2, MAGNESIUM ION, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
1H3E
DownloadVisualize
BU of 1h3e by Molmil
Tyrosyl-tRNA synthetase from Thermus thermophilus complexed with wild-type tRNAtyr(GUA) and with ATP and tyrosinol
Descriptor: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, ADENOSINE-5'-TRIPHOSPHATE, TYROSYL-TRNA SYNTHETASE, ...
Authors:Cusack, S, Yaremchuk, A, Kriklivyi, I, Tukalo, M.
Deposit date:2002-08-28
Release date:2002-10-27
Last modified:2019-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Class I Tyrosyl-tRNA Synthetase Has a Class II Mode or tRNA Recognition
Embo J., 21, 2002
6FSB
DownloadVisualize
BU of 6fsb by Molmil
Influenza B/Memphis/13/03 endonuclease with I38T mutation
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Polymerase acidic protein
Authors:Cusack, S, Speranzini, V.
Deposit date:2018-02-19
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
6FS8
DownloadVisualize
BU of 6fs8 by Molmil
Influenza B/Memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (BXA)
Descriptor: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein
Authors:Cusack, S, Speranzini, V.
Deposit date:2018-02-19
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
6FS6
DownloadVisualize
BU of 6fs6 by Molmil
Influenza A/California/04/2009 (pH1N1) endonuclease with bound inhibitor, baloxavir acid (BXA)
Descriptor: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
Authors:Cusack, S, Speranzini, V.
Deposit date:2018-02-19
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
6FS9
DownloadVisualize
BU of 6fs9 by Molmil
Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
Descriptor: Baloxavir acid, CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Cusack, S, Speranzini, V.
Deposit date:2018-02-19
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
6FS7
DownloadVisualize
BU of 6fs7 by Molmil
Influenza A/California/04/2009 (pH1N1) endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
Descriptor: Baloxavir acid, MANGANESE (II) ION, Polymerase acidic protein,Polymerase acidic protein
Authors:Cusack, S, Speranzini, V.
Deposit date:2018-02-19
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
6QCS
DownloadVisualize
BU of 6qcs by Molmil
Influenza B polymerase pre-initiation complex
Descriptor: 3 end, 5 end, Capped RNA, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2018-12-30
Release date:2019-06-05
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural snapshots of actively transcribing influenza polymerase.
Nat.Struct.Mol.Biol., 26, 2019
6QCT
DownloadVisualize
BU of 6qct by Molmil
Influenza B polymerase elongation complex
Descriptor: 3 end, 5 end, MAGNESIUM ION, ...
Authors:Cusack, S, Kouba, T.
Deposit date:2018-12-30
Release date:2019-06-05
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural snapshots of actively transcribing influenza polymerase.
Nat.Struct.Mol.Biol., 26, 2019

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon