2QFD
| Crystal structure of the regulatory domain of human RIG-I with bound Hg | 分子名称: | MERCURY (II) ION, Probable ATP-dependent RNA helicase DDX58 | 著者 | Cui, S, Lammens, A, Lammens, K, Hopfner, K.P. | 登録日 | 2007-06-27 | 公開日 | 2008-02-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I. Mol.Cell, 29, 2008
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2QFB
| Crystal structure of the regulatory domain of human RIG-I with bound Zn | 分子名称: | Probable ATP-dependent RNA helicase DDX58, ZINC ION | 著者 | Cui, S, Lammens, A, Lammens, K, Hopfner, K.P. | 登録日 | 2007-06-27 | 公開日 | 2008-02-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I. Mol.Cell, 29, 2008
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3EIK
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3OCI
| Crystal structure of TBP (TATA box binding protein) | 分子名称: | 1,2-ETHANEDIOL, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | 著者 | Cui, S, Wollmann, P, Moldt, M, Hopfner, K.-P. | 登録日 | 2010-08-10 | 公開日 | 2011-07-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP. Nature, 475, 2011
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3OSY
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5KWB
| Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 1.9 angstrom, molecular replacement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Spike glycoprotein, ... | 著者 | Guan, H, Wojdyla, J.A, Wang, M, Cui, S. | 登録日 | 2016-07-17 | 公開日 | 2017-06-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1 Nat Commun, 8, 2017
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8GQC
| Crystal structure of the SARS-unique domain (SUD) of SARS-CoV-2 (1.35 angstrom resolution) | 分子名称: | Papain-like protease nsp3 | 著者 | Qin, B, Li, Z, Aumonier, S, Wang, M, Cui, S. | 登録日 | 2022-08-30 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target. Nat Commun, 14, 2023
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8HBL
| Crystal structure of the SARS-unique domain (SUD) of SARS-CoV-2 (1.58 angstrom resolution) | 分子名称: | GLYCEROL, LITHIUM ION, Non-structural protein 3, ... | 著者 | Qin, B, Li, Z, Aumonier, S, Wang, M, Cui, S. | 登録日 | 2022-10-29 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target. Nat Commun, 14, 2023
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2W4R
| Crystal structure of the regulatory domain of human LGP2 | 分子名称: | MERCURY (II) ION, PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, SULFATE ION | 著者 | Pippig, D.A, Hellmuth, J.C, Cui, S, Kirchhofer, A, Lammens, K, Lammens, A, Schmidt, A, Rothenfusser, S, Hopfner, K.P. | 登録日 | 2008-12-01 | 公開日 | 2009-02-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA. Nucleic Acids Res., 37, 2009
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5GMQ
| Structure of MERS-CoV RBD in complex with a fully human antibody MCA1 | 分子名称: | 1,2-ETHANEDIOL, MCA1 heavy chain, MCA1 light chain, ... | 著者 | Chen, C, Wang, J.M, Zou, T.T, Gao, X.P, Cui, S, Jin, Q. | 登録日 | 2016-07-15 | 公開日 | 2017-05-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset. J. Infect. Dis., 215, 2017
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4I2L
| New HIV entry inhibitor MTSFT/T23 complex | 分子名称: | GP41, inhibitor MTSFT | 著者 | Yao, X, Chong, H.H, Waltersperger, S, Wang, M.T, He, Y.X, Cui, S. | 登録日 | 2012-11-22 | 公開日 | 2014-01-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.426 Å) | 主引用文献 | Potent antiviral activity of the novel HIV entry inhibitor MTSFT To be Published
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4ZHS
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4ZIC
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5GNB
| Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 2.3 angstrom, native-SAD phasing) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Guan, H, Wojdyla, J.A, Wang, M, Cui, S. | 登録日 | 2016-07-20 | 公開日 | 2017-06-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1 Nat Commun, 8, 2017
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5GRB
| Crystal structure of 2C helicase from enterovirus 71 (EV71) bound with ATPgammaS | 分子名称: | EV71 2C ATPase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ZINC ION | 著者 | Guan, H.X, Tian, J, Qin, B, Wojdyla, J, Wang, M.T, Cui, S. | 登録日 | 2016-08-09 | 公開日 | 2017-05-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | 主引用文献 | Crystal structure of 2C helicase from enterovirus 71 SCI ADV, 3, 2017
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5GQ1
| Crystal structure of 2C helicase from enterovirus 71 (EV71) | 分子名称: | Genome polyprotein, PHOSPHATE ION, ZINC ION | 著者 | Guan, H.X, Tian, J, Qin, B, Wojdyla, J, Wang, M.T, Cui, S. | 登録日 | 2016-08-05 | 公開日 | 2017-05-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | Crystal structure of 2C helicase from enterovirus 71 SCI ADV, 3, 2017
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5H7Z
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5H7Y
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3G9A
| Green fluorescent protein bound to minimizer nanobody | 分子名称: | Green fluorescent protein, Minimizer | 著者 | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | 登録日 | 2009-02-13 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.614 Å) | 主引用文献 | Modulation of protein properties in living cells using nanobodies Nat.Struct.Mol.Biol., 17, 2010
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8IT0
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-2) | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-03-21 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8ISY
| Cryo-EM structure of free-state Crt-SPARTA | 分子名称: | Piwi domain-containing protein, TIR domain-containing protein | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-03-21 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8ISZ
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA monomer | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-03-21 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8IT1
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form) | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-03-21 | 公開日 | 2023-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8K9G
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-1) | 分子名称: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | 著者 | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | 登録日 | 2023-08-01 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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3K1K
| Green fluorescent protein bound to enhancer nanobody | 分子名称: | Enhancer, Green Fluorescent Protein | 著者 | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | 登録日 | 2009-09-28 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Modulation of protein properties in living cells using nanobodies Nat.Struct.Mol.Biol., 17, 2010
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