4WOZ
 
 | | Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine | | Descriptor: | 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, N-acetylneuraminate lyase | | Authors: | Liu, W.D, Guo, R.T, Cui, Y.F, Chen, X, Wu, Q.Q, Zhu, D.M. | | Deposit date: | 2014-10-17 | | Release date: | 2015-10-21 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine
to be published
|
|
1C8J
 | | CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F) | | Descriptor: | CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Liu, Y, Jiang, F, Guo, Q, Chen, X, Jin, J, Sun, Y, Rao, Z. | | Deposit date: | 2000-05-31 | | Release date: | 2001-05-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F)
To be Published
|
|
4AY9
 | | Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE-STIMULATING HORMONE RECEPTOR, FOLLITROPIN SUBUNIT BETA, ... | | Authors: | Jiang, X, Liu, H, Chen, X, He, X. | | Deposit date: | 2012-06-19 | | Release date: | 2012-08-08 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of Follicle-Stimulating Hormone in Complex with the Entire Ectodomain of its Receptor.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
1WWN
 | | NMR Solution Structure of BmK-betaIT, an Excitatory Scorpion Toxin from Buthus martensi Karsch | | Descriptor: | Excitatory insect selective toxin 1 | | Authors: | Wu, H, Tong, X, Chen, X, Zhang, Q, Zheng, X, Zhang, N, Wu, G. | | Deposit date: | 2005-01-10 | | Release date: | 2006-01-17 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of BmK-betaIT, an excitatory scorpion beta-toxin without a 'hot spot' at the relevant position
Biochem.Biophys.Res.Commun., 349, 2006
|
|
1HKA
 | | 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE | | Descriptor: | 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE | | Authors: | Xiao, B, Shi, G, Chen, X, Yan, H, Ji, X. | | Deposit date: | 1998-09-29 | | Release date: | 1999-06-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents.
Structure Fold.Des., 7, 1999
|
|
7QZQ
 | | Crystal structure of the kelch domain of human KBTBD12 | | Descriptor: | 1,2-ETHANEDIOL, Kelch repeat and BTB domain-containing protein 12, SODIUM ION | | Authors: | Manning, C.E, Chen, Z, Chen, X, Bradshaw, W.J, Bakshi, S, Mckinley, G, Chalk, R, Burgess-Brown, N, von Delft, F, Bullock, A.N. | | Deposit date: | 2022-01-31 | | Release date: | 2022-05-04 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structure of the kelch domain of human KBTBD12
To Be Published
|
|
7RR5
 | | Structure of ribosomal complex bound with Rbg1/Tma46 | | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | | Authors: | Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H. | | Deposit date: | 2021-08-09 | | Release date: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells.
Cell Rep, 37, 2021
|
|
7RSL
 | | Seipin forms a flexible cage at lipid droplet formation sites | | Descriptor: | Seipin | | Authors: | Arlt, H, Sui, X, Folger, B, Adams, C, Chen, X, Remme, R, Hamprecht, F.A, DiMaio, F, Liao, M, Goodman, J.M, Farese Jr, R.V, Walther, T.C. | | Deposit date: | 2021-08-11 | | Release date: | 2022-02-09 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Seipin forms a flexible cage at lipid droplet formation sites.
Nat.Struct.Mol.Biol., 29, 2022
|
|
1YVL
 | | Structure of Unphosphorylated STAT1 | | Descriptor: | 5-residue peptide, GOLD ION, Signal transducer and activator of transcription 1-alpha/beta | | Authors: | Mao, X, Ren, Z, Parker, G.N, Sondermann, H, Pastorello, M.A, Wang, W, McMurray, J.S, Demeler, B, Darnell Jr, J.E, Chen, X. | | Deposit date: | 2005-02-16 | | Release date: | 2005-03-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural bases of unphosphorylated STAT1 association and receptor binding.
Mol.Cell, 17, 2005
|
|
5GWZ
 | | The structure of Porcine epidemic diarrhea virus main protease in complex with an inhibitor | | Descriptor: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, PEDV main protease | | Authors: | Wang, F, Chen, C, Yang, K, Liu, X, Liu, H, Xu, Y, Chen, X, Liu, X, Cai, Y, Yang, H. | | Deposit date: | 2016-09-14 | | Release date: | 2017-03-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.444 Å) | | Cite: | Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus
J. Med. Chem., 60, 2017
|
|
2E0H
 | |
1FIO
 | | CRYSTAL STRUCTURE OF YEAST T-SNARE PROTEIN SSO1 | | Descriptor: | SSO1 PROTEIN, ZINC ION | | Authors: | Munson, M, Chen, X, Cocina, A.E, Schultz, S.M, Hughson, F.M. | | Deposit date: | 2000-08-04 | | Release date: | 2000-10-11 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Interactions within the yeast t-SNARE Sso1p that control SNARE complex assembly.
Nat.Struct.Biol., 7, 2000
|
|
1GH2
 | | Crystal structure of the catalytic domain of a new human thioredoxin-like protein | | Descriptor: | THIOREDOXIN-LIKE PROTEIN | | Authors: | Jin, J, Chen, X, Guo, Q, Yuan, J, Qiang, B, Rao, Z. | | Deposit date: | 2000-11-01 | | Release date: | 2001-05-01 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Crystal structure of the catalytic domain of a human thioredoxin-like protein.
Eur.J.Biochem., 269, 2002
|
|
4EXP
 | | Structure of mouse Interleukin-34 in complex with mouse FMS | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor | | Authors: | Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X. | | Deposit date: | 2012-04-30 | | Release date: | 2012-05-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
|
|
4GHQ
 | | Crystal structure of EV71 3C proteinase | | Descriptor: | 3C proteinase | | Authors: | Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T. | | Deposit date: | 2012-08-08 | | Release date: | 2013-06-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4GHT
 | | Crystal structure of EV71 3C proteinase in complex with AG7088 | | Descriptor: | 3C proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | Authors: | Chen, C, Wu, C, Cai, Q, Li, N, Peng, X, Cai, Y, Yin, K, Chen, X, Wang, X, Zhang, R, Liu, L, Chen, S, Li, J, Lin, T. | | Deposit date: | 2012-08-08 | | Release date: | 2013-06-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir
Acta Crystallogr.,Sect.D, 69, 2013
|
|
5KOC
 | | Pavine N-methyltransferase in complex with S-adenosylmethionine pH 7 | | Descriptor: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | | Authors: | Torres, M.A, Hoffarth, E, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | | Deposit date: | 2016-06-30 | | Release date: | 2016-09-07 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.293 Å) | | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
|
|
5KOK
 | | Pavine N-methyltransferase in complex with Tetrahydropapaverine and S-adenosylhomocysteine pH 7.25 | | Descriptor: | (1~{R})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, (1~{S})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, Pavine N-methyltransferase, ... | | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | | Deposit date: | 2016-06-30 | | Release date: | 2016-09-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.792 Å) | | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
|
|
5KPC
 | | Pavine N-methyltransferase H206A mutant in complex with S-adenosylmethionine pH 6 | | Descriptor: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | | Deposit date: | 2016-07-03 | | Release date: | 2016-09-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
|
|
5KN4
 | | Pavine N-methyltransferase apoenzyme pH 6.0 | | Descriptor: | Pavine N-methyltransferase | | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | | Deposit date: | 2016-06-27 | | Release date: | 2016-09-07 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
|
|
5KPG
 | | Pavine N-methyltransferase in complex with S-adenosylhomocysteine pH 7 | | Descriptor: | Pavine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | | Deposit date: | 2016-07-04 | | Release date: | 2016-09-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.
J.Biol.Chem., 291, 2016
|
|
6CIM
 | | Pre-Reaction Complex, RAG1(E962Q)/2-nicked/intact 12/23RSS complex in Mn2+ | | Descriptor: | DNA (5'-D(*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 23RSS substrate forward strand, ... | | Authors: | Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W. | | Deposit date: | 2018-02-24 | | Release date: | 2018-04-25 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Cracking the DNA Code for V(D)J Recombination.
Mol. Cell, 70, 2018
|
|
1IK1
 | | Solution Structure of an RNA Hairpin from HRV-14 | | Descriptor: | 5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3' | | Authors: | Huang, H, Alexandrov, A, Chen, X, Barnes III, T.W, Zhang, H, Dutta, K, Pascal, S.M. | | Deposit date: | 2001-05-01 | | Release date: | 2001-07-18 | | Last modified: | 2018-01-31 | | Method: | SOLUTION NMR | | Cite: | Structure of an RNA hairpin from HRV-14.
Biochemistry, 40, 2001
|
|
5WWM
 | | Crystal structure of the TPR domain of Rrp5 | | Descriptor: | SULFATE ION, rRNA biogenesis protein RRP5 | | Authors: | Ye, K, Chen, X. | | Deposit date: | 2017-01-03 | | Release date: | 2017-01-25 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.809 Å) | | Cite: | Correction: Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
|
|
1MI8
 | | 2.0 Angstrom crystal structure of a DnaB intein from Synechocystis sp. PCC 6803 | | Descriptor: | DnaB intein | | Authors: | Ding, Y, Chen, X, Ferrandon, S, Xu, M, Rao, Z. | | Deposit date: | 2002-08-22 | | Release date: | 2003-08-19 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing
J.Biol.Chem., 278, 2003
|
|
