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8WQC
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BU of 8wqc by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
To Be Published
8WQI
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BU of 8wqi by Molmil
Local refinement of FEM1B bound with the C-degron of CUX1
Descriptor: Protein CASP, Protein fem-1 homolog B
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Local refinement of FEM1B bound with the C-degron of CUX1
To Be Published
8WQG
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BU of 8wqg by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (4.09 Å)
Cite:cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
To Be Published
8WQB
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BU of 8wqb by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
Descriptor: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
To Be Published
8WQA
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BU of 8wqa by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
Descriptor: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
To Be Published
8WQD
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BU of 8wqd by Molmil
Local refinement of FEM1B bound with the C-degron of CCC89
Descriptor: Coiled-coil domain-containing protein 89, Protein fem-1 homolog B
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Local refinement of FEM1B bound with the C-degron of CCC89
To Be Published
3LUT
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BU of 3lut by Molmil
A Structural Model for the Full-length Shaker Potassium Channel Kv1.2
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ...
Authors:Chen, X, Ni, F, Wang, Q, Ma, J.
Deposit date:2010-02-18
Release date:2010-06-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Proc.Natl.Acad.Sci.USA, 107, 2010
6V0V
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BU of 6v0v by Molmil
Cryo-EM structure of mouse WT RAG1/2 NFC complex (DNA0)
Descriptor: CALCIUM ION, DNA (30-MER), V(D)J recombination-activating protein 1, ...
Authors:Chen, X, Yang, W, Gellert, M.
Deposit date:2019-11-19
Release date:2020-01-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Chen, X, Walters, K.J.
Deposit date:2020-04-13
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6AKO
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BU of 6ako by Molmil
Crystal Structure of FOXC2 DBD Bound to DBE2 DNA
Descriptor: DNA (5'-D(CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Forkhead box protein C2, ...
Authors:Chen, X, Wei, H, Li, J, Liang, X, Dai, S, Jiang, L, Guo, M, Chen, Y.
Deposit date:2018-09-03
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Structural basis for DNA recognition by FOXC2.
Nucleic Acids Res., 47, 2019
6WJN
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BU of 6wjn by Molmil
SD-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Chen, X, Walters, K.J.
Deposit date:2020-04-14
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6AKP
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BU of 6akp by Molmil
Crystal Structural of FOXC2 DNA binding domain bound to PC promoter
Descriptor: DNA (5'-D(AP*CP*AP*CP*AP*AP*AP*TP*AP*TP*TP*TP*GP*TP*GP*T)-3'), Forkhead box protein C2, MAGNESIUM ION
Authors:Chen, X, Wei, H, Li, J, Liang, X, Dai, S, Jiang, L, Guo, M, Chen, Y.
Deposit date:2018-09-03
Release date:2019-02-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.323 Å)
Cite:Structural basis for DNA recognition by FOXC2.
Nucleic Acids Res., 47, 2019
2KQZ
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BU of 2kqz by Molmil
Solution structure of the Rpn13 DEUBAD domain
Descriptor: Proteasomal ubiquitin receptor ADRM1
Authors:Chen, X, Lee, B, Finley, D, Walters, K.J.
Deposit date:2009-11-25
Release date:2010-05-26
Last modified:2015-12-23
Method:SOLUTION NMR
Cite:Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2.
Mol.Cell, 38, 2010
2KR0
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BU of 2kr0 by Molmil
Solution structure of the proteasome ubiquitin receptor Rpn13
Descriptor: Proteasomal ubiquitin receptor ADRM1
Authors:Chen, X, Lee, B, Finley, D, Walters, K.J.
Deposit date:2009-11-25
Release date:2010-05-26
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2.
Mol.Cell, 38, 2010
8GI3
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BU of 8gi3 by Molmil
Crystal structure of RhoA mutant L69P complexed with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
Authors:Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J.
Deposit date:2023-03-13
Release date:2024-03-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Ras-like GTPases mutants structure
To be published
8GI6
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BU of 8gi6 by Molmil
Crystal structure of RhoA mutant L69R complexed with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
Authors:Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J.
Deposit date:2023-03-13
Release date:2024-03-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Ras-like GTPases mutant structures
To be published
4JHD
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BU of 4jhd by Molmil
Crystal Structure of an Actin Dimer in Complex with the Actin Nucleator Cordon-Bleu
Descriptor: Actin-5C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chen, X, Ni, F, Wang, Q.
Deposit date:2013-03-04
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural basis of actin filament nucleation by tandem w domains.
Cell Rep, 3, 2013
2NBW
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BU of 2nbw by Molmil
Solution structure of the Rpn1 T1 site with the Rad23 UBL domain
Descriptor: 26S proteasome regulatory subunit RPN1, UV excision repair protein RAD23
Authors:Chen, X, Walters, K.J.
Deposit date:2016-03-14
Release date:2016-07-20
Last modified:2016-08-17
Method:SOLUTION NMR
Cite:Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
Structure, 24, 2016
2NBV
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BU of 2nbv by Molmil
Solution structure of the Rpn13 Pru domain engaging the hPLIC2 UBL domain
Descriptor: Proteasomal ubiquitin receptor ADRM1, Ubiquilin-2
Authors:Chen, X, Walters, K.J.
Deposit date:2016-03-12
Release date:2016-07-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
Structure, 24, 2016
2NBU
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BU of 2nbu by Molmil
Solution structure of the Rad23 ubiquitin-like (UBL) domain
Descriptor: UV excision repair protein RAD23
Authors:Chen, X, Walters, K.J.
Deposit date:2016-03-12
Release date:2016-07-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
Structure, 24, 2016
2OZ4
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BU of 2oz4 by Molmil
Structural Plasticity in IgSF Domain 4 of ICAM-1 Mediates Cell Surface Dimerization
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB FRAGMENT LIGHT CHAIN, ...
Authors:Chen, X, Kim, T.D, Carman, C.V, Mi, L, Song, G, Springer, T.A.
Deposit date:2007-02-23
Release date:2007-10-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QTO
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BU of 2qto by Molmil
An anisotropic model for potassium channel KcsA
Descriptor: POTASSIUM ION, Voltage-gated potassium channel
Authors:Chen, X, Poon, B.K, Dousis, A, Wang, Q, Ma, J.
Deposit date:2007-08-02
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Normal-mode refinement of anisotropic thermal parameters for potassium channel KcsA at 3.2 A crystallographic resolution
Structure, 15, 2007
5IRS
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BU of 5irs by Molmil
crystal structure of the proteasomal Rpn13 PRU-domain
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Proteasomal ubiquitin receptor ADRM1
Authors:Chen, X, Shi, K, Walters, K, Aihara, H.
Deposit date:2016-03-14
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.
Structure, 24, 2016
8GRD
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BU of 8grd by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
Authors:Chen, X, Sun, P, Ding, J.
Deposit date:2022-09-01
Release date:2022-11-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
7DWS
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BU of 7dws by Molmil
The structure of T4 Lysozyme I3C/C54T/R125C/E128C complex with Zinc ions
Descriptor: Endolysin, ZINC ION
Authors:Chen, X, Chen, S.
Deposit date:2021-01-17
Release date:2021-06-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rationally designed protein cross-linked hydrogel for bone regeneration via synergistic release of magnesium and zinc ions.
Biomaterials, 274, 2021

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