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5UP5
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BU of 5up5 by Molmil
Solution structure of the de novo mini protein EHEE_rd1_0284
分子名称: EHEE_rd1_0284
著者Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
登録日2017-02-01
公開日2017-07-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UP1
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BU of 5up1 by Molmil
Solution structure of the de novo mini protein EEHEE_rd3_1049
分子名称: EEHEE_rd3_1049
著者Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
登録日2017-02-01
公開日2017-07-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
6D0T
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BU of 6d0t by Molmil
De novo design of a fluorescence-activating beta barrel - BB1
分子名称: BB1
著者Dou, J, Vorobieva, A.A, Sheffler, W, Doyle, L.A, Park, H, Bick, M.J, Mao, B, Foight, G.W, Lee, M, Carter, L, Sankaran, B, Ovchinnikov, S, Marcos, E, Huang, P, Vaughan, J.C, Stoddard, B.L, Baker, D.
登録日2018-04-10
公開日2018-09-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
2IX2
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BU of 2ix2 by Molmil
Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus
分子名称: DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C
著者Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H.
登録日2006-07-05
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus.
Acta Crystallogr.,Sect.F, 62, 2006
5UOI
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BU of 5uoi by Molmil
Solution structure of the de novo mini protein HHH_rd1_0142
分子名称: HHH_rd1_0142
著者Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
登録日2017-01-31
公開日2017-07-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UYO
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BU of 5uyo by Molmil
Solution NMR structure of the de novo mini protein HEEH_rd4_0097
分子名称: HEEH_rd4_0097
著者Lemak, A, Rocklin, G.J, Houliston, S, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H.
登録日2017-02-24
公開日2017-07-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
1UW7
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BU of 1uw7 by Molmil
Nsp9 protein from SARS-coronavirus.
分子名称: NSP9
著者Sutton, G, Fry, E, Carter, L, Sainsbury, S, Walter, T, Nettleship, J, Berrow, N, Owens, R, Gilbert, R, Davidson, A, Siddell, S, Poon, L.L.M, Diprose, J, Alderton, D, Walsh, M, Grimes, J.M, Stuart, D.I.
登録日2004-01-30
公開日2004-02-20
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Nsp9 Replicase Protein of Sars-Coronavirus, Structure and Functional Insights
Structure, 12, 2004
2W04
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BU of 2w04 by Molmil
Co-complex Structure of Achromobactin Synthetase Protein D (AcsD) with citrate in ATP binding site from Pectobacterium Chrysanthemi
分子名称: ACSD, CITRATE ANION
著者Schmelz, S, McMahon, S.A, Kadi, N, Song, L, Oves-Costales, D, Oke, M, Liu, H, Johnson, K.A, Carter, L, White, M.F, Challis, G.L, Naismith, J.H.
登録日2008-08-08
公開日2009-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Acsd Catalyzes Enantioselective Citrate Desymmetrization in Siderophore Biosynthesis
Nat.Chem.Biol., 5, 2009
2W03
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BU of 2w03 by Molmil
Co-complex Structure of Achromobactin Synthetase Protein D (AcsD) with adenosine, sulfate and citrate from Pectobacterium Chrysanthemi
分子名称: ACSD, ADENOSINE, CITRIC ACID, ...
著者Schmelz, S, McMahon, S.A, Kadi, N, Song, L, Oves-Costales, D, Oke, M, Liu, H, Johnson, K.A, Carter, L, White, M.F, Challis, G.L, Naismith, J.H.
登録日2008-08-08
公開日2009-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Acsd Catalyzes Enantioselective Citrate Desymmetrization in Siderophore Biosynthesis
Nat.Chem.Biol., 5, 2009
2VA8
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BU of 2va8 by Molmil
DNA Repair Helicase Hel308
分子名称: SKI2-TYPE HELICASE, SULFATE ION
著者Johnson, K.A, Richards, J, Liu, H, McMahon, S, Oke, M, Carter, L, Naismith, J.H, White, M.F.
登録日2007-08-30
公開日2008-01-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the DNA Repair Helicase Hel308 Reveals DNA Binding and Autoinhibitory Domains.
J.Biol.Chem., 283, 2008
8SKD
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BU of 8skd by Molmil
Solution Structure of the model miniprotein EEHEE_rd4_0871
分子名称: Miniprotein EEHEE_rd4_0871
著者Houliston, S, Carter, L, Baker, D, Arrowsmith, C.H, Rocklin, G.
登録日2023-04-19
公開日2024-04-24
実験手法SOLUTION NMR
主引用文献Solution Structure of the model miniprotein EEHEE_rd4_0871
To Be Published
8SKX
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BU of 8skx by Molmil
Solution structure of the model miniprotein HHH_rd4_0518
分子名称: Miniprotein HHH_rd4_0518
著者Houliston, S, Carter, L, Baker, D, Arrowsmith, C.H, Rocklin, G.
登録日2023-04-20
公開日2024-04-24
実験手法SOLUTION NMR
主引用文献Solution structure of the model miniprotein HHH_rd4_0518
To Be Published
8SKE
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BU of 8ske by Molmil
Solution structure of the model miniprotein EEHEE_rd4_0642
分子名称: Miniprotein EEHEE_rd4_0642
著者Houliston, S, Carter, L, Baker, D, Arrowsmith, C.H, Rocklin, G.
登録日2023-04-19
公開日2024-04-24
実験手法SOLID-STATE NMR
主引用文献Solution structure of the model miniprotein EEHEE_rd4_0642
To Be Published
5VMR
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BU of 5vmr by Molmil
Receptor binding domain of BoNT/B in complex with mini-protein binder Bot.2110.4
分子名称: Bot.2110.4, Botulinum neurotoxin type B
著者Jin, R, Lam, K, Yao, G.
登録日2017-04-28
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Massively parallel de novo protein design for targeted therapeutics.
Nature, 550, 2017
7LMX
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BU of 7lmx by Molmil
A HIGHLY SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 WITH A DISULFIDE
分子名称: Integrin inhibitor
著者Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D.
登録日2021-02-06
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
7LMV
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BU of 7lmv by Molmil
SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6
分子名称: Integrin inhibitor
著者Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D.
登録日2021-02-05
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
7M0Q
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BU of 7m0q by Molmil
Crystal structure of deep network hallucinated protein 0738_mod
分子名称: Network hallucinated protein 0738_mod
著者Pellock, S.J, Bera, A.K, Anishchenko, I, Baker, D.
登録日2021-03-11
公開日2021-12-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献De novo protein design by deep network hallucination.
Nature, 600, 2021
7M5T
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BU of 7m5t by Molmil
Solution NMR structure of de novo designed protein 0515
分子名称: De novo designed protein 0515
著者Ramelot, T.A, Hao, J, Baker, D, Montelione, G.T.
登録日2021-03-24
公開日2021-12-15
最終更新日2022-07-27
実験手法SOLUTION NMR
主引用文献De novo protein design by deep network hallucination.
Nature, 600, 2021
3FFE
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BU of 3ffe by Molmil
Structure of Achromobactin Synthetase Protein D, (AcsD)
分子名称: AcsD
著者McMahon, S.A, Liu, H, Carter, L, Oke, M, Johnson, K.A, Schmelz, S, Challis, G.L, White, M.F, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF)
登録日2008-12-03
公開日2009-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis
Nat.Chem.Biol., 5, 2009
8UR5
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BU of 8ur5 by Molmil
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
8UR7
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BU of 8ur7 by Molmil
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
5VID
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BU of 5vid by Molmil
Receptor binding domain of BoNT/B in complex with mini-protein binder Bot.0671.2
分子名称: Bot.0671.2, Botulinum neurotoxin type B
著者Jin, R, Lam, K, Yao, G.
登録日2017-04-15
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Massively parallel de novo protein design for targeted therapeutics.
Nature, 550, 2017
5VLI
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BU of 5vli by Molmil
Computationally designed inhibitor peptide HB1.6928.2.3 in complex with influenza hemagglutinin (A/PuertoRico/8/1934)
分子名称: 2,5,8,11-TETRAOXATRIDECANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bernard, S.M, Wilson, I.A.
登録日2017-04-25
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Massively parallel de novo protein design for targeted therapeutics.
Nature, 550, 2017
7UHB
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BU of 7uhb by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175 (local refinement of the RBD and AHB2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, Spike glycoprotein
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-03-26
公開日2022-06-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022
7UHC
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BU of 7uhc by Molmil
SARS-CoV-2 spike in complex with AHB2-2GS-SB175
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Multivalent miniprotein inhibitor AHB2-2GS-SB175, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-03-26
公開日2022-06-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Sci Transl Med, 14, 2022

 

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