5VMR
Receptor binding domain of BoNT/B in complex with mini-protein binder Bot.2110.4
Summary for 5VMR
Entry DOI | 10.2210/pdb5vmr/pdb |
Descriptor | Botulinum neurotoxin type B, Bot.2110.4 (3 entities in total) |
Functional Keywords | mini-protein binder, inhibitor, toxin |
Biological source | Clostridium botulinum More |
Cellular location | Botulinum neurotoxin B light chain: Secreted. Botulinum neurotoxin B heavy chain: Secreted: P10844 |
Total number of polymer chains | 4 |
Total formula weight | 114925.83 |
Authors | |
Primary citation | Chevalier, A.,Silva, D.A.,Rocklin, G.J.,Hicks, D.R.,Vergara, R.,Murapa, P.,Bernard, S.M.,Zhang, L.,Lam, K.H.,Yao, G.,Bahl, C.D.,Miyashita, S.I.,Goreshnik, I.,Fuller, J.T.,Koday, M.T.,Jenkins, C.M.,Colvin, T.,Carter, L.,Bohn, A.,Bryan, C.M.,Fernandez-Velasco, D.A.,Stewart, L.,Dong, M.,Huang, X.,Jin, R.,Wilson, I.A.,Fuller, D.H.,Baker, D. Massively parallel de novo protein design for targeted therapeutics. Nature, 550:74-79, 2017 Cited by PubMed: 28953867DOI: 10.1038/nature23912 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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